Shaquille O’Neal was never suspended for drug use of any kind during his decorated 19-year NBA career. The rugged 7-foot-1, 325-pound Hall of Fame center freely acknowledged playing through pain and openly worried about damage to his kidneys and liver from his prolonged use of legal anti-inflammatory medications.

He also recently recounted on “Inside the NBA” a bizarre story about testing positive for cocaine ahead of the 1996 Olympics. The result was thrown out — and never publicized — because O’Neal told officials he’d eaten a poppy seed muffin shortly before the test.

Never mind that while poppy seeds can trigger a false positive test for opioids such as morphine or codeine, they can’t do the same for cocaine, which is identified in drug tests by the presence of its major metabolite, benzoylecgonine.

So in his recounting of an episode from nearly 30 years ago, O’Neal was wrong either about the illegal substance for which he tested positive or about what he ingested that caused the false positive. Perhaps he just meant to say codeine rather than cocaine.

Point being, recollections can be fuzzy, and O’Neal isn’t immune to such fuzziness, something to keep in mind when listening to the four-time NBA champion ‘fess up to his use of painkillers on this week’s “Armchair Expert With Dax Shepard” podcast.

O’Neal toggled between referring to opioid painkillers such as oxycodone and powerful, nonsteroidal anti-inflammatories such as Indocin. He said he used opioids when recovering from injuries and took NSAIDs throughout his career.

But he also said his doctor told him he was addicted to painkillers, leading to “a heated discussion.” O’Neal didn’t feel high, he said, even when he would take more than the prescribed dose. “I would do homeboy math,” he said. “If it said take one, I’m taking three.”

“It was a club sandwich, fries and two pills for 19 years.”

O’Neal first discussed painkillers during his four-part HBO documentary “Shaq,” which premiered in 2022, and on the podcast Shepard mostly asked him to expand on what he’d said then about the potential damage to internal organs, the warnings from doctors and his current regrets.

In the documentary, O’Neal had this to say: “Sometimes I couldn’t play if I didn’t take it. All it did was mask the pain…. Had a lot of painkillers. I got limited kidney stuff now going on. I don’t have the full range, but I took so many painkillers that [doctors are] saying, ‘Hey, man, we don’t need you taking that stuff now. You got to be careful.’

“My kidneys are kind of just chilling out right now,” he continued. “I don’t want to flare ‘em back up.”

Both opioids and NSAIDs can cause kidney and liver damage, and O’Neal didn’t specify on the podcast which substances caused him the most concern. He said he struggled with accepting that he might have an addiction, eventually concluding, “I had to have them. So, is that addiction?”

And he hid the use of painkillers from his wife and kids, although he said “the trainers knew.”

As far back as 2000 — a year when O’Neal was the NBA‘s most valuable player and led the Lakers to the first of three consecutive championships — he expressed concern about the dangers of anti-inflammatories.

O’Neal suspected that the kidney disease that threatened the life of fellow NBA star Alonzo Mourning might be the result of anti-inflammatories and said he would stop taking them.

Two years later, however, O’Neal had resumed NSAID use. After a stomach ailment he originally believed was an ulcer, diagnostic tests were done on his kidneys and liver.

He described the results to The Times thusly: “I’m not great, but I’m cool.”

O’Neal was playing with a badly aching arthritic big toe, a sprained wrist and a handful of unlisted bangs and bruises. He needed the pills, although it was unclear whether he was referring to painkillers, anti-inflammatories or both.

“I tried to stay off of them, but if I don’t take them I can’t move or play,” he said in 2002. “I was taking them. When my stomach was giving me problems I had to get the test.”

O’Neal has long championed nonprescription means of addressing pain. He’s been the spokesperson for the topical analgesic Icy Hot since 2003 and he spoke on Capitol Hill in 2016, plugging efforts to give police better tools to recognize when drivers are under the influence of drugs. He pledged two years of funding for officers to become drug recognition experts.

O’Neal’s comments on Shepard’s podcast are a clear indication that his use of painkillers and NSAIDs continues to weigh heavily on his mind. He added that these days he relaxes with a different vice: a hookah.

“I’ve never been into weed,” he said. “Hookah, it enables me to follow the routine of sit your ass down.”

Source: https://www.latimes.com/sports/story/2025-08-13/shaquille-oneal-painkillers-opioids-regrets-kidneys

34 comments

  1. I can’t even imagine the gargantuan shits that were building up in this man’s GI system with painkillers in the mix

  2. For some reason my brain associated O’Neal to Royce O’Neal and I was like “meh”.

    Now that I know it’s Shaquille O’Neal, meh.

  3. It would mean more if “not reading all that crowd” could read above 3rd grade level. frickin oxygen wasters

  4. Most NBA players are doped up to the eyeballs to stay on the court all season but Shaq also didn’t take care of his body with diet or rehab so he was definitely masking a lot of pain from shit he neglected

  5. > And he hid the use of painkillers from his wife and kids, although he said “the trainers knew.”

    I’m being dead ass serious when I type this….I just saw a story today of him allegedly throwing shit bombs at a former trainer. SO, say the trainers knew….the fuck were they going to do about it?!?!? More importantly, who were they going to tell? The head coach who as focused on winning games? The management who could lift their heads and easily fill the trainer’s positions? They going to the league and get blackballed???

    Again, Shaq was just accused of flinging shit toilet paper or whatever: https://streamable.com/66umiq

    YOU THINK HE’S TRYING TO HELP SHAQ BREAK AN ADDICTION?!?!?

  6. I’m sympathetic towards opiate addicts but shaq really is the biggest clown ever…

  8. Is it just me or has there been allot of post featuring players from 20’years ago and off court transgressions ? Seems allot of Kobe, TMac and more TMZ fodder then usual

  10. Damn basketball players have a unique body problem in being that tall and big and also just working the body to exhaustion. No wonder he was on pain killers. 

  12. Do they have a ready story like this to counter anything that comes out ?
    Quite fascinating.
    Shit fetish > painkiller addiction

  20. Sometimes I hear people say “Shaq should’ve been the GOAT,” but I think it’s honestly a miracle Shaq played as well as he did for as long as he did. When you are that large of a person, everything becomes a problem. Your knees, your heart, your back, your legs…and despite all the problems, he played for roughly 2 decades, with one of the highest peaks we’ve ever seen.

    Shaq sounds like an asshole but I hope his body is at least somewhat functional, given his size, injury history, and age.

  22. This is crazy damage control for that story coming out about him wiping his ass and throwing the soiled toilet paper at Lakers trainer Gary Vitti.

  28. Well this giant of a man playing professional sports, im not surprised his body wanted to give up on him. At least he was open about it.

  31. Really interesting take that Alonso might have got sick that way, very possible.

    My regular blue collar dad took nsaids, every day I’d guess, for decades, he had to go to the emergency room one day for what ended up being many ulcers.

    Shit is no joke

  32. NSAIDS can also cause ulcers, so makes sense he had those two but kind of weird that no doctors told him to stop taking them when he got one.

  34. Definitely ran into Shaq at a hole in the wall hookah bar in Baton Rouge in the early-mid 2010’s. Funny how that’s come up as his vice. Dude was laid out in a L shaped bench probably designed for half a dozen people and he took up the whole booth. 

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