Cleveland Guardians vs Arizona Diamondbacks Predictions Today | Best MLB Picks For 8/19/25

If you are looking for MLB picks, predictions and best bets for today’s Cleveland Guardians vs Arizona Diamondbacks matchup, we have you covered! Our MLB handicapping experts discuss the spread and total from a sports betting perspective, sharing their picks and predictions vs the current odds.

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⚾️ Cleveland Guardians vs Arizona Diamondbacks Betting Preview 8/19/25

Get ready for an exciting MLB matchup tonight as the Cleveland Guardians (64-60) take on the Arizona Diamondbacks (60-66) at Chase Field in Phoenix, Arizona.

Date: Tuesday, August 19, 2025
First Pitch: 9:40 p.m. ET
Venue: Chase Field — Phoenix, AZ

Watch on TV
MLB Network, plus regional feeds: ARID (Arizona Diamondbacks broadcast) and CLEG (Cleveland Guardians broadcast)

Listen on Radio
Guardians Radio Network via WTAM / WMMS (English) with Tom Hamilton & Jim Rosenhaus
WARF (Spanish; with Rafa Hernández-Brito & Carlos Baerga)

Watch or Stream Online
Fubo streaming service (with free trial, region-dependent)

Guardians TV and DBacks.tv for regional streaming (subject to local rights)
Wikipedia
fubo

Odds: Spread & Total (as of today):
Spread (Run Line)
+1.5 (Guardians) at around +162 to +165
D-backs −1.5 at about −195 to −200

Total (Over/Under)
8.5 to 9.0 runs — e.g., 8.5 (Over −118 / Under −104), or 9.0 as per some sources

Fun & Interesting Facts
The Diamondbacks (aka the D-backs) are one of MLB’s younger franchises, founded in 1998—and they won the World Series just four seasons later in 2001, becoming the fastest expansion team to do so

The Guardians have embraced a rich Cleveland heritage and are second in the AL Central entering tonight, while the Diamondbacks have struggled slightly—hovering under .500 and enduring a recent four-game skid

Team Twitter Hashtags
#Guardians (Cleveland Guardians)
#Dbacks or #Diamondbacks (Arizona Diamondbacks)

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