Chicago Cubs vs San Francisco Giants Predictions Today | Best MLB Picks For 8/27/25

Chicago Cubs vs San Francisco Giants Predictions Today | Best MLB Picks For 8/27/25

If you are looking for MLB picks, predictions and best bets for today’s Chicago Cubs vs San Francisco Giants matchup, we have you covered! Our MLB handicapping experts discuss the spread and total from a sports betting perspective, sharing their picks and predictions vs the current odds.

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Chicago Cubs vs San Francisco Giants • August 27, 2025 • MLB Regular Season

First Pitch & Venue

First Pitch: Wednesday, August 27, 2025 — 9:45 PM ET

Venue: Oracle Park, San Francisco, California—a picturesque ballpark known for its beautiful bay views and iconic design.

How to Watch

TV Broadcast:

NBC Sports Bay Area (NBCSBA) for Giants fans
Marquee Sports Network for Cubs viewers
Radio: KNBR (680/104.5) and Cubs affiliates

Betting Snapshot

Moneyline:

Cubs: –128
Giants: +108
Run Line: Cubs –1.5 (+131)
Total Runs (O/U): 8.5 runs (Over –109, Under –111)
Alternate listing: Cubs –132; Giants +110; Total = 8

Team Twitter Hashtags

Chicago Cubs: #Cubs, #GoCubs
San Francisco Giants: #Giants, #SFGiants

Use these for better reach and engagement on YouTube and social media.

Interesting Facts & Highlights

Giants’ Blockbuster Trade:
San Francisco made headlines by acquiring All-Star Rafael Devers midseason in a major trade—marking a bold strategic move for their 2025 campaign.

Cubs’ Strong Season Metrics:
As of late August, the Cubs boast a 76–56 record (with a split of 41–25 at home and 35–31 on the road), and vary in performance depending on uniform choice—highlighting unique historical and brand elements in their identity.

Close Series Recently:
Since mid-2024, the Cubs and Giants have met ten times, with San Francisco holding a slight edge at 6–4, showcasing a competitive and evolving matchup.

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