49ers vs. Cardinals Preview, Injury News, Score Prediction, Analysis, Keys To Game For NFL Week 3

49ers vs. Cardinals Preview, Injury News, Score Prediction, Analysis, Keys To Game For NFL Week 3

Coming up on today’s San Francisco 49ers report. We’re going to preview this Ner’s Cardinals game. This is a huge matchup inside the NFC West. It is the home opener for San Francisco at Levi Stadium, the site of Super Bowl 60. Kickoff is set for 4:25 p.m. Eastern, 1:25 p.m. on the West Coast out there in Santa Clara. and the 49ers going into this game as of right now. One and a half point favorites with the overunder set at 43 and a half. This is the best preview that you’ll find on YouTube for this game, analysis, matchups to watch, keys to the game, injury news, and a whole lot more. So, continue to hang out here with me. But I do want to begin here, get those predictions in. Who you got? I’ll give you my prediction at the end of the show. Type a arri for the Cardinals, SF for the 49ers. And with that, let’s get this preview underway. [Music] All right, let’s do it. Welcome into the San Francisco 49ers report. My name is Chase Senior. As always, no matter where you are, how you’re tuned in, thank you so much for making today’s show a part of your day. And I can’t wait to dive into this one because this is a really big matchup inside this division between these two rivals inside the NFC West, the 49ers and the Cardinals. Two teams also that are undefeated to start the 2025 campaign as they’re 2 and 0 going into Sunday. Don’t forget to subscribe to the channel and join us. First of all, when you hit that sub button, we give you year round and daily coverage of the Niners, but also we go live for every single Niners game, and we’re running it back with another watch party. We’ll see you on Sunday. Also, thanks to all the real ones for your continued support. Last night, we surpassed 170,000 subscribers. Speaking of the NFC West and why this game is so big and really all of the divisional games for San Francisco in 2025, I think are going to be closely contested and they’re going to have a lot of implications because I think this division is tight and I think this division is wide open. It wouldn’t surprise me if any team listed here to my right ends up winning the NFC West crown here in 2025 because frankly I think all of these teams are very solid in their own respective ways. San Francisco 2-0, Cardinals 2 and 0, Rams 2 and 0, and the Seahawks getting on the board with a win over Pittsburgh over the weekend. They are now 1 and one. Every team in the NFC West in week two came out of week two with a victory. And the Niners bad taste from 2024 when they think about the Arizona Cardinals, right? because San Francisco surprisingly swept in the season series against Arizona last year. Up until this point going into week three, here’s what the Cardinals have done so far. A week one win on the road against the New Orleans Saints 20-13. Like the Ner’s win over the Saints, that game came down to the wire at the Superdome in New Orleans. Week two, it was the Cardinals home opener and they beat the Carolina Panthers 27 to22. They went up big, then Carolina rallied, nearly came back to steal that game, but Arizona able to close that game out. And a constant for the Cardinals this year and something that I’m going to continue to kind of monitor as the season progresses. I really like their defensive line talent, their defensive line depth with this scheme led by Jonathan Ganon who is the head coach of Arizona. Of course, he is a defensiveminded andor oriented head coach. Used to be the def the defensive coordinator for the Philadelphia Eagles. He’s going to run a little bit of that 34 hybrid front. And he has this team playing really well in the trenches. And this is something that the Cardinals have been building over the last few years as it is now Ganon’s third year in the desert. Kyler Murray through the first two games has been very accurate hovering around 70% completion percentage. And the two trays on offense, Trey McBride, the tight end, Trey Benson, the young running back, they have been balling. The pass game goes through McBride second to George Kill on average annual value for highest paid tight ends in the NFL. And then Benson, a player who the Cardinals have really been a fan of. He’s starting to come into his own and they have a good running back combo in that backfield with Kyler Murray with James Connor also getting a bulk share of the carries as well. And in a loaded NFC West, I do think this is going to be one of the more competitive divisions in football in 2025. The Cardinals are always looked at as the little brother, the redheaded stepchild. I have nothing against Gingers or Redheads, but nobody seems to take the Cardinals seriously year in and year out because over the course of franchise history, they haven’t had a lot of success, right? But against the 49ers recently, they have. They’ve been a feisty team. They’ve been a team with Cliff Kingsberry and with Jonathan Ganon, they’ve started seasons well and then they’ve kind of tailed off late, but they’ve been in these playoff hunts late in the year. And this year in 2025, they’re a quality ball club. And this season, it is a big year for Kyler Murray and Jonathan Ganon. Obviously, they’re kind of tied together because Kyler is the quarterback, Ganon the head coach. But if Kyler doesn’t play well this year, wouldn’t surprise me if the Cardinals after 2025 try to bring in and find another franchise quarterback. I think Ganon has a little bit of a longer leash, but if the Cardinals fall apart, maybe they try to find a new head coach as well with their GM, Monty Ozenford, who is a big Jonathan Ganon fan and they do have a lot of familiar familiarity and a history together. Something to be aware of with Arizona. I talked about how they struggle to close out season strong, whether it be under Cliff Kingsbury, whose NFL offense I don’t really like, or Jonathan Ganon, who’s a defensive guy, as compared to Kingsberry being an offensive guy, is that in the first two games of the year, there has been a pattern with Arizona. The Cardinals in week one had to hold on until the final snap to beat the Saints. Spencer Rattler drove New Orleans down the field and frankly I think New Orleans should have tied that game up. They lost by seven, but Rattler threw a dime ball in the end zone and it was dropped. Arizona escapes with the victory. Then in week two, they take this big lead over Carolina. The Panthers didn’t want to fall into that dreaded 0 and2 hole and so the Panthers rally back and they nearly mounted a pretty epic comeback before that Cardinals defense able to close the door shut. They forced a couple of giveaways and forced Bryce Young into some mistakes on Sunday at home. And so the Niners have done a good job of closing games. The Cardinals have not. And if this game is close, that is something to remember and be cognizant of. Also, with Arizona’s offense, this is a Kyler problem because he’s shorter and doesn’t always see the field well. This is an offensive coordinator problem. Cardinals fans don’t love their OC. It’s a scheme issue, but there has been a lack of wide receiver usage to start the year for Arizona. When they pass it, the offense is going through Trey McBride, and he’s a stellar player, but they drafted Marvin Harrison in the 2024 draft. He’s been slow to get his career going outside of him. They have players like Greg Dorch, who hasn’t been used a lot so far this year. And so we’ll see if they really try to get the pass game going to the wide outs to see if they can press and try to test this Niner secondary. Of course, a big question for San Francisco going into this game. Will Brock Pury play quarterback and start? Will it be the M. Jones show again? Brock Pury suffered that turftoe injury against the Seattle Seahawks according to a variety of reports. It’s a two to five week injury. He missed the New Orleans game. That’s one week. And so he might come back for this week. I would say the chances of that are very slim or his absence could be extended for this game and beyond. Here’s the latest from Albert Brerier, NFL insider for Sports Illustrated. I was told he will be out two to three weeks. Of note, Ian Rapaort’s timeline was two to five. Maybe it’s one of those deals where he gets back out there on the practice field and does light work at the end of this week. But my sense is the 49ers want to sit him at least two games and maybe a third. And of course, if Brock Pury cannot play, M. Jones will get his second consecutive start. San Francisco also has to be very careful about managing Pertie’s turftoe injury. And San Francisco kind of dodged a bullet. Joe Burrow has turf toe, but with the severity of it, he could be out for the rest of the year, has to undergo surgery. Whereas for Pury, best case scenario, more of a minor turf toe injury, which could still keep him out for a couple of games. I was so impressed with how M. Jones played against the Saints. It was really the best game that I’ve seen him play in his NFL career. Kyle Shanahan elevated him with the scheme and with his play calling and play designs. M. Jones was awesome on third downs. I really like the ball distribution as he found eight different players with a pass and a reception on Sunday. 26 of 39, 279 yards, three touchdowns, no picks, and a rating of 113.1 in that spot on the road. Backup quarterback about as good as he could have played given the circumstances. And on third down, M. Jones was surgical, especially in that twominute fast-paced drive right before halftime in which Mack went seven of nine, converted a couple of big third downs and led the Niners right down the field for a huge touchdown drive. But on third down throughout the game, M. Jones really excelled. Big reason for that, able to throw a touch, timing, accuracy, being able to layer throws and process what the defense was doing. Most importantly, the offensive line held up in front of him and Mack on third down 7 to 12, a buck 21. All three of his touchdowns through the air came on third down and he had a passer rating of 132.2. Another reason why he played about as good as you could have asked for. And what I really like about what Mack did and how Kyle Shanahan helped him and how his other supporting players around him assisted him. The offensive line needed to hold up against the Saints and it did. The protection for the most part was really good. The strip sack on M. Jones, I’m not putting that on Colton McKiv. That’s on Mack. He held on to the ball way too long. I also liked how Kyle Shanahan trusted Mack with this play calling. Mac Jones threw the ball 23 times in the first half. You don’t see that a lot with Brock Pury. I’m not alluding to the fact that Kyle Shanahan doesn’t trust Brock Pury, but he trusted M. Jones, and it was good to see that well-rounded ball distribution. What I like about M. Jones, and why I thought it was a good fit for him coming to the NerS, he can run this offense by playing point guard. I’ve used that term a lot. get the ball out on time, early, fast, accurately to playmakers, lay your throws in there as well, so that you can hit your receivers at multiple levels and areas of the field. And so we saw all of that on Sunday. He does what Brock Pery does very well. Layers those balls with beautiful touch. Probably has a stronger arm and a better long ball than Brock Party as far as being able to throw it deeper. And then that third down execution was big time. Max’s performance against the Saints was a great example of why Kyle Shanahan is elite, one of the top head coaches in the NFL, and one of the most respected offensive minds in the league because these quarterback whisperers are able to elevate and maximize quarterbacks of all types of styles and quarterbacks of all types of different skill sets. Think about the quarterbacks who Kyle Shanahan has been able to maximize and have play well for him as a head coach when he’s been calling plays. CJ Bethard and Nick Mullen put up some crazy numbers under Kyle Shanahan. And so Kyle Shanahan’s been able to maximize the likes of CJ Bethard, Nick Mullins, Jimmy Garopolo, Brock Pury was top five and MVP voting in 2023. I know Sam Darnold didn’t play a lot for the NerS, but he credits his time with Kyle Shanahan and Brock Pury for being able to revive his career where he went to Minnesota, put up huge numbers, and then he got a bag from the Seattle Seahawks. And then on Sunday, you saw what Shanahan did with M. Jones. That is highlevel coaching right there. And it was on display on Sunday, and it’s been on display with Kyle Shanahan running the show. a look back to what happened in week five last year between the Niners and the Cardinals. Let’s get to that. I’m not going to get to the week 18 matchup because you got to take it with a grain of salt. I mean, Joshua Dobs played, the Niners had mailed in their season and the Cardinals didn’t have anything to play for. Nick Sorenson was a dead duck at the defensive coordinator spot and San Francisco’s defense was embarrassingly bad in the regular season finale. But when these two teams were full strength, they played in week five last year and the Cardinals stunned the Niners with a 24-23 victory. San Francisco scored 23 points in the first half. They were shut out and blanked after halftime. San Francisco in the process because of that blew a 23-10 lead and they spoiled a game in which they scored 23 first half points. You had Demador Lenor block a field goal and return it for a touchdown. And then late after halftime when the offense couldn’t do anything, the defense collapsed. And then also late, San Francisco had to go for it a lot on fourth downs because Jake Moody got hurt. He was never the same. And really, that was the beginning to the end of his Niners career. The 49ers defense last year collapsed, fell apart, and choked in games. There were personnel issues, there were depth issues, there were scheme breakdowns, but coaching malpractice was a problem under Nick Sorenson. Well, what have we seen to start 2025? Under Robert Salah, who’s a huge upgrade over Sorenson, this defense, instead of collapsing late in ball games, has been able to close games out. The Nick Bosa pressure and fumble forced in week one. Bosa did it again in week two. And then Bryce sub able to polish that game off with the strip sack of Spencer Rattler with an unbelievably fast get off. A huge key to winning this game. Speaking of Robert Salah and his defense will be containing Kyler Murray. The 49ers struggles against mobile quarterbacks have been well documented over the last few years. This is where running the wide nine really can hurt San Francisco because their defensive linemen are spread out. It leads to wide openen running lanes for the quarterback and the vision is a little bit easier for the quarterback to take off and run if nothing is open downfield. When you’re also running that wide nine, you get up field so quickly, leaving that middle area of the field vacant. And sometimes San Francisco doesn’t have disciplined pass rush lanes. Overall from 2022 to 2024, the Niners have allowed the 12th most rushing yards per game to quarterbacks, about 28.5 according to NFL NextGen stats. That is often due to schematic gaps in containing the edge rather than raw talent deficits. And so why had the 49ers struggled so much against mobile quarterbacks? When you’re running this wide nine, the thought process is to be on the attack. It’s to be aggressive and to get after the quarterback. But with that aggression, it can sometimes burn you because you get up field so quickly and then quarterbacks are able to step up when the lanes are wider as compared to a regular 4-3 or a 34. They can take off and run. But pass rush lane discipline is going to be so crucial in this game for San Francisco. Let’s get to some injury news as well. Brock Pury dealing with the turf toe. Kyle Yuseek suffered a concussion early in the game against New Orleans. One of the Niner special teams aces, Siron Neil, also suffered a concussion. Ben Bart is going to be out for a while due to an ankle. So Connor Kby will start at left guard. And then Jawan Jennings, the ners will monitor his status throughout the week. ankle. He’s dayto-day. I didn’t put George KD on here because he’s on IR and he’s out at least the next three games after he missed that Saints game. On the Cardinals injury front, Arizona in that win against Carolina, lost three quarterbacks in week two. Max Melton, a player who I really like coming out of college, Will Johnson, who fell to the second round out of Michigan. He was looked at as one of the top corners in the 2025 class, but because of injuries, he fell. But the Cardinals love him and he’s been balling. And then Garrett Wilh Williams also got hurt along the defensive line in that game against Carolina. LJ Collier left the game with a knee injury. And then prior to the year, defensive tackle Walter Nolan, who Arizona drafted in the first round out of Miss. I really liked him in the pre-draft for San Francisco. He was placed on pup. And then Bal Nicholls started the year on pup as well. We’re only getting started for our Niners Cardinals week three preview. Don’t go anywhere. Coming up next, my keys to the game, matchups to watch out for for San Francisco to beat Arizona and stay undefeated in their home opener at Levi Stadium, the site of Super Bowl 60. Before we do that, today’s 49ers report brought to you by Prize Picks. You and I make decisions every day, but on Prize Picks, being right can get you paid. Don’t miss any of the excitement this season on prize picks where it’s good to be right. Millions of users are already signed up. 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Real Money Sports Action made easy. Claim your $50 now. prize.coms. It is good to be right. All right, to the back half of the show. This is the San Francisco 49ers report. My name is Chase Senior. Thanks for hanging out here with me. What a matchup we have in week three. San Francisco 49ers playing host to the Arizona Cardinal. A huge game inside the NFC West. And here’s what the Niners have to do to beat Arizona in addition to matchups to look out for. You look at the NFC West standings going into Sunday. The Niners are 2-0. The Cardinals are 2-0. The Rams are 2-0. And the Seahawks are 1 and one. By season’s end, I really have no idea who’s going to win this division. And we’re going to see some fireworks in the NFC West all year because I think this division is very competitive and there are some highlevel teams and with that a lot of these games inside the division are going to be close. With that, let’s flip the page to my keys to the game. I have five of them for all of you. And when you watch this show, I want you to become a more informed Niner fan. And so hopefully we can do that with our analysis and our breakdowns here. Key to the game number one, San Francisco has to contain quarterback Kyler Murray. San Francisco over the last few years as they’ve run this wide nine, they have really struggled against mobile quarterbacks who have been able to burn the Ner’s defense with their feet and with their legs. In week four last year, week five last year, October 5th, 2024, the 49ers blew a 23-10 lead against Arizona. They scored all of those points in the first half. They got blanked after halftime and they were falling apart at the seams, offense, defense, and on special teams. And the Cardinals were able to get on the board early and strike first, but the game’s first touchdown thanks to a 50 yard Kyler Murray rushing touchdown. And San Francisco’s angles on that play were poor. But this is all a part of a bigger problem for the 49ers when they go up against these quarterbacks who are fleet of foot because they run this wide n. And this is where the wide nine can really hurt San Francisco here because with their front four alignment oftentimes their defensive linemen are so spread out and their job is to pin their ears back, be aggressive, get after the quarterback and get up field to try to collapse the pocket. But when you do that with that wide nine alignment against a quarterback like Kyler Murray who is so twitchy in how he’s able to run and with his footwork, even if the pocket does break down, he sees that sliver of daylight to carve through that wide nine. And then even if you’re doing your job in coverage and everybody is holding up because the pass rush gets up field, that middle area of the field is left vacant, leading to chunk running plays for quarterbacks like Kyler Murray. So disciplined pass rush lanes going to be important. Pass rush lane integrity is going to be important in this game. And setting the edge against Kyler is something that San Francisco is going to have to do. From 2022 to 2024, the 49ers allowed the 12th most rushing yards per game. Two quarterbacks, 28 and a half per game, and it’s often due to those schematic gaps. Excuse me. So, you look at this, and this is kind of the game plan that I would put together. This is how the 49ers can contain Kyler Murray in week three on Sunday and how they can stop the rushing attack and keep him from burning this Ner’s defense with his legs. You have to have those disciplined pass rush lanes. You have to set the edge and keep him contained in the pocket. Don’t let him break contain. What he also really likes to do is to create plays out of structure and improvisationally, especially given his lack of height. He doesn’t see the field well, especially with some bodies in front of him as the pocket gets muddied. So, if he starts to feel that the pocket is breaking down or pressure is getting to him, he’s going to run around to try to create plays downfield and make plays with his feet. He is a true dual threat quarterback. When this Niners pass rush gets upfield, that’s fine, right? Because this is part of the Ner scheme and what makes them such a violent pass rushing team at times. But the linebacker security at that second level is going to have to be there. And San Francisco will have to tackle well. Wouldn’t be surprised if Robert Salah has a quarterback spy from time to time, but you don’t want to always do that because it takes a defender away from your coverage unit. And then another way to contain Kyler Murray in the pocket and not allow him to hurt you with his feet and his legs is to run some twists and stunts so that he gets confused with what he’s seeing. you clog up his vision line and you blur his vision line, but then you run those twist stunts up front and he’s not really sure where the pressure is coming from and sometimes he can lack that processing power. Key to the game number two, the 49ers, like they did against the Saints, have to protect M. Jones. M. Jones is a completely different quarterback when he’s clean compared to when he’s under duress. And this is a Cardinals team in 2025. I started to notice this during the preseason. They have a talented, violent, physical, and deep defensive line. And Jonathan Ganon has been able to really craft a defense that is growing, progressing, and getting better since coming to the Cardinals as head coach after he was previously the defensive coordinator for the Philadelphia Eagles. And what he preaches is a defense that plays fast and physical. And so, if the Cardinals are able to generate a pass rush on M. Jones, it could really throw this Ner’s offense out of whack and throw a wrench into their offensive plans. I showed you these numbers going into that Saints game, but they still apply, especially with what we saw against New Orleans when M. Jones was kept clean. M. Jones against pressure in 2024. When he was kept clean, you see how the completion percentage is so much higher, 72.1% compared to when he’s under pressure, 38.9%. when he’s not blitzed. Completion percentage 69% when he was blitzed, 56.6%. Of course, for Mack, he always has to limit the turnovers because that’s been a problem throughout his career. In 2023, when he was kept clean, a similar story here, ladies and gentlemen, 71.8% completion rate, but when he was under pressure, it plummeted to 46.2. when he was not blitzed in 2023 with the Patriots 65.9% when he was blitzed 61.7%. And so there is a consistent theme there whether Mack has played for New England or Jacksonville much better quarterback when he is kept clean in the pocket. And against the Saints among the Ner’s seven highest graded players, six of them were offensive linemen. really good sign for San Francisco here. And hopefully they can duplicate that performance. This is also going to be a big game coming up for the rookie seventh round pick out of Iowa, Connor Colby, who’s stepping in for Ben Bart, who got hurt against New Orleans at left guard. Jonathan Ganon knows that and so he’s going to try to stack the box on the side of Conor Colby, come up with some defensive play calls to really confuse a rookie like that. And Kobe has to hold up. I went back and watched the tape. I mean, he was really good against New Orleans. And he’s a huge upgrade over Ben Bar who to no one’s surprised is injured again. And against the Saints, Colby pass blocking grade according to PFF, 73.6. He had zero penalties, zero sacks, no hits given up, zero pressures on 61 snaps. The Cardinals up front, here are some players to look out for here. Darius Robinson going into year two. Cardinals high on him. Stock is up. Baron Browning a really good player. M Wilson, Akeem Davis Gaither, and then Arizona brought in Josh Schwe this off season. He had a career year under Jonathan Ganon in 2022 when Ganon was the DC for the Eagles. Sweat had 11 sacks. He was good in 2023, excellent in 2024. A big reason why the Eagles won that Super Bowl. The Cardinals needed to get better at that pass rushing spot, which is why they gave Joshuet $19 million. And so far so good for him. He had a big strip sack of Bryce Young in that game in week two. Key to the game number three for the Ners, takeaway tight end Trey McBride. The entire Cardinals passing offense goes through McBride. It’s one of the best tight ends in the NFL. Probably a top five guy in that realm of George KD. Brock Bowers has really good size at 64246. He moves very well. What’s interesting about McBride, not the best red zone option throughout his career, he hasn’t scored a lot of touchdowns, but Kyler Murray loves throwing him the rock. Whether it’s down the seam, down the numbers, into the flat, he can pick up yards after the catch. He is a matchup nightmare for linebackers and smaller nickel corners. So far this season, 12 catches for a buck 39. Kyler Murray’s going to look his way on that first read almost every single time. And what’s odd about Arizona’s offense so far this year is the lack of wide receiver involvement. And up until this point, Marvin Harrison Jr. has been somewhat of a disappointment with what he did at Ohio State, how early the Cardinals drafted him, and what other rookies in that receiver class from 2024 are doing so far. Malik Neighbors is a top five, top 10 wide out. Brian Thomas is an absolute stud. Marvin Harrison Jr. for whatever reason hasn’t been able to find his rhythm, groove, or confidence with Arizona. And that connection between Kyler and him hasn’t been on point so far through two games. Only seven catches for 98 yards along a 45. That’s good. That’s an explosive, but the production somewhat limited. Michael Wilson is the Cardinals second leading white out. He only has two catches for 16 yards in two games. Good size though. Su uh 62213. And then Greg Dorch, he’s played very well against the Niners. He’s a smaller player who’s shiftier who the Cardinals are sometimes going to try to get involved with bubble screens and some gadget plays 575. But home run playmaking ability through two games. He only has two catches for nine yards. And so matching up against McBride going to be a big matchup for Fred Warner Dwinners and I imagine at times Upton Stout the rookie slot corner will be one-on-one with Trey McBride too and he’s going to have to hold up. Key to the game number four, stop this Cardinals rushing attack. The pass game really hasn’t been explosive or all that impressive. Part of that is because of the aforementioned lack of wide receiver involvement and the offense going through. Trey McBride, Kyler Murray has really tried to emphasize being accurate with the ball, getting rid of the ball early and not turning it over. And look, it’s worked so far. The Cardinals are 2 and 0. But a staple of this Cardinals offense is their ground game. And they’re going to lean on that a lot. Trey Benson is a player who I like coming out of Florida State. And the Cardinals have been waiting for him to break out. Looks as though the breakout year might be here. 11 carries for 83 yards this season. 52 of them came on one play. And then Mr. Steady, Mr. Reliable, the cancer survivor. Unbelievable story. Who is closing in, I think, on becoming the all-time leading touchdown score at running back for Arizona in franchise history. It’s James Connor. And the 49ers have struggled against James Connor because of his physical running style. And last year they were so bad at tackling. This year they’ve gotten better, but they’re going to have to tackle in space and in the trenches when things are condensed against Arizona. Conor 61233. So he’s really a bull at that running back spot. He’s been a workhorse the last few years. 23 carries, 73 yards, and a touchdown this season. And then you have to remember that Kyler Murray is such a dangerous runner. Those quick feet, he can really take off in a blink. 510, that’s generous. Kyler Murray is like 59 on a good day. But with him not being able to see it all that well, that’s why him extending plays in the pocket with his feet and running makes him difficult to defend. He has 14 carries for 70 yards so far this year. And then lastly, what I really liked about Kyle Shanahan’s game plan and play calling with M. Jones at quarterback, he leaned into a strength of M. Jones. And that’s Mack being able to run the system, play point guard, and distribute the pill. And against the Saints, eight different players caught a pass from M. Jones. And while San Francisco doesn’t have its juggernaut players to catch footballs right now, no George KD, no Brandon Aayuk, Ricky Pearl has been incredible. Joan Jennings was awesome against the Saints. The Ners, I think, are better off right now with a well-rounded offensive attack, and that’s helping to make up for not having some of their stars. And it makes them difficult to defend because you really do have to defend every blade of grass from sideline to sideline vertically. And then M. Jones with that processing ability able to lay your throws with Christian McAffrey running the ball and catching it. You’re posing as an offense so many threats to the opposing defense. And you have to do that against a team like Arizona. They’re really good at all three levels. And Buddha Baker, Kus Campbell, they’re still studs. Buddha Baker obviously not as old as Klayas Cam Campbell, but he’s still one of the top safeties and playmakers in the game on defense. And Kus Campbell, he’s in his late 30s. So disruptive as he’s on his way to the Hall of Fame. All right, predict the score. Cardinals, Ners, get those score predictions in. I think San Francisco wins this game. And I’m going to go Niners 25, Cardinals 20. I do think it is a close game because I think people are underrating the Cardinals. I think it comes down to some lateg game execution. The Niners have been better there the first two games of the year as compared to Arizona. And with overall talent and coaching, I just think San Francisco is better than Arizona and well positioned right now. So, M. Jones gets another win. San Francisco moves to 3 and 0. That’s my prediction. Thanks for watching the preview. [Music]

49ers vs. Cardinals preview on the NFl week 3 schedule right here on the 49ers Report with the latest 49ers news, 49ers rumors, Arizona Cardinals news & Arizona Cardinals rumors. Visit https://prizepicks.onelink.me/LME0/CLNS and use code CLNS and get $50 in lineups when you play your first $5 lineup! Our San Francisco 49ers vs. Arizona Cardinals preview will take a look at the 49ers vs. Cardinals keys to the game, matchups to watch, 49ers vs. Cardinals history, the 49ers roster, Cardinals roster, 49ers schedule and Cardinals schedule.

49ers vs. Cardinals game info and 49ers vs. Cardinals betting odds:
49ers vs. Cardinals
Kickoff: 4:25p ET / 1:25p PT on Sunday
Levi’s Stadium, Santa Clara
49ers: -1.5

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San Francisco 49ers 2025 schedule:
Week 1: at Saints
Week 2: at Saints
Week 3: vs. Cardinals
Week 4: vs. Jaguars
Week 5: at Rams (TNF)
Week 6: at Buccaneers
Week 7: vs. Falcons (SNF)
Week 8: at Texans
Week 9: at Giants
Week 10: vs. Rams
Week 11: at Cardinals
Week 12: vs. Panthers (MNF)
Week 13: at Browns
Week 14: BYE
Week 15: vs. Titans
Week 16: at Colts (MNF)
Week 17: vs. Bears (SNF)
Week 18: vs. Saints

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