The MLB Wild Card Round begins on Tuesday, Sept. 29 with a quartet of Game 1’s.

Teams in this round play a best-of-three series, with all three games taking place in the home stadium of the better-seeded team. Those series areChicago White Sox atHouston Astros,Boston Red Sox at New York Yankees, Philadelphia Phillies at Atlanta Braves and Chicago CubsatSan Diego Padres.

The two division winners with the best records in each league (Tampa Bay Rays, Cleveland Guardians,Milwaukee Brewers, Los Angeles Dodgers) all get a chance to rest their regulars and set up their rotations for the next round, where they’ll square off with the winners beginning Saturday, Oct. 3.

For more on the MLB playoffs, check out eachteam’s odds to win the World Series.

Odds by DraftKings

and are accurateas of time of publication.

To win series: Astros 145, White Sox +125

Correct score for series: Astros 2-0 +235, Astros 2-1 +240

Correct score for series: White Sox 2-1 +300, White Sox 2-0 +300

Game 1: Tuesday, Sept. 29, 5 p.m. ET

Moneyline:Astros 136, White Sox +113

Run Line:Astros (-1.5) +158, White Sox (+1.5) -193

Over/Under 8.0 runs:O -110/U -110

Game 2: Wednesday, Sept. 30, 5 p.m. ET

*Game 3: Thursday, Oct. 1,5 p.m. ET(if necessary)

To win series: Yankees 170, Red Sox +140

Correct score for series: Yankees 2-0 +185, Yankees 2-1 +240

Correct score for series: Red Sox 2-1 +320, Red Sox 2-0 +400

Game 1: Tuesday, Sept. 29, 8 p.m. ET

Moneyline:Yankees 154, Red Sox +127

Run Line:Yankees (-1.5) +153, Red Sox (+1.5) -186

Over/Under 6.5 runs:O -112/U -108

Game 2: Wednesday, Sept. 30,8 p.m. ET

*Game 3: Thursday, Oct. 1,8 p.m. ET(if necessary)

To win series: Braves 125, Phillies +105

Correct score for series: Braves 2-0 +210, Braves 2-1 +290

Correct score for series: Phillies 2-1 +225, Phillies 2-0 +380

Game 1: Tuesday, Sept. 29, 2 p.m. ET

Moneyline:Braves 200, Phillies +163

Run Line:Braves (-1.5) +119, Phillies (+1.5) -143

Over/Under 6.5 runs:O -122/U +102

Game 2: Wednesday, Sept. 30, 2 p.m. ET

*Game 3: Thursday, Oct. 1,2 p.m. ET(if necessary)

To win series: Padres 120, Cubs +100

Correct score for series: Padres 2-0 +260, Padres 2-1 +245

Correct score for series: Cubs 2-1 +290, Cubs 2-0 +275

Game 1: Tuesday, Sept. 29, 10 p.m. ET

Moneyline:Padres 127, Cubs +106

Run Line:Padres (-1.5) +167, Cubs (+1.5) -204

Over/Under 7.0 runs:O -119/U -101

Game 2: Wednesday, Sept. 30, 10 p.m. ET

*Game 3: Thursday, Oct. 1,10 p.m. ET(if necessary)

Copyright © 2026 ESPN Internet Ventures. All rights reserved.