It’s Week 5! Our writers and editors successfully rebounded from a rough Week 3 by all finishing .500 or better on our picks in Week 4. We will look to continue that momentum as we pick all 15 games—the Panthers and Chiefs are on their byes—in Week 5. 

For the second consecutive week, the Sunday slate kicks off at 9:30 a.m. ET with a London game, this time featuring the Eagles and Jaguars. The Eagles are in transition after trading Cam Jurgens and seeing Lane Johnson retire while the Jaguars look like one of the NFL’s best teams so far. This is reflected in our predictions, as our whole panel has picked the Jaguars to win. Later in the early slate, the Packers will look to hold off Ben Johnson and the Bears while the Raiders will try to keep their surprising start going against the Patriots. 

This week really heats up in the late afternoon on Sunday, when the 49ers head to Seattle for a key divisional matchup between these two NFC West rivals. The Seahawks went 2–1 vs. the 49ers last year, but our experts are split on who will get the win this time around. The game is followed by two intriguing prime-time games; the Ravens at the Falcons on Sunday night and the Rams hosting the Bills on Monday. 

Here’s who we have making picks this season:

Albert Breer, senior writer
Eva Geitheim, news writer
Mitch Goldich, senior editor
Mike Kadlick, senior news writer
Gilberto Manzano, staff writer
Conor Orr, senior writer
John Pluym, managing editor
Matt Verderame, staff writer

NFL, MMQB, Week 5

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All picks are straight up. Visit SI Betting for picks against the spread and much more gambling content. 

Buccaneers at CowboysAlbert Breer: CowboysEva Geitheim: CowboysMitch Goldich: CowboysMike Kadlick: CowboysGilberto Manzano: CowboysConor Orr: CowboysJohn Pluym: CowboysMatt Verderame: CowboysEagles vs. Jaguars (London, England)Albert Breer: JaguarsEva Geitheim: JaguarsMitch Goldich: JaguarsMike Kadlick: JaguarsGilberto Manzano: JaguarsConor Orr: JaguarsJohn Pluym: JaguarsMatt Verderame: JaguarsBears at PackersAlbert Breer: BearsEva Geitheim: BearsMitch Goldich: BearsMike Kadlick: BearsGilberto Manzano: PackersConor Orr: BearsJohn Pluym: BearsMatt Verderame: BearsTexans at TitansAlbert Breer: TexansEva Geitheim: TexansMitch Goldich: TexansMike Kadlick: TexansGilberto Manzano: TexansConor Orr: TexansJohn Pluym: TexansMatt Verderame: TexansBengals at DolphinsAlbert Breer: BengalsEva Geitheim: BengalsMitch Goldich: BengalsMike Kadlick: BengalsGilberto Manzano: BengalsConor Orr: BengalsJohn Pluym: BengalsMatt Verderame: BengalsRaiders at PatriotsAlbert Breer: PatriotsEva Geitheim: RaidersMitch Goldich: RaidersMike Kadlick: PatriotsGilberto Manzano: PatriotsConor Orr: RaidersJohn Pluym: PatriotsMatt Verderame: PatriotsVikings at SaintsAlbert Breer: SaintsEva Geitheim: VikingsMitch Goldich: VikingsMike Kadlick: SaintsGilberto Manzano: VikingsConor Orr: VikingsJohn Pluym: VikingsMatt Verderame: VikingsBrowns at JetsAlbert Breer: BrownsEva Geitheim: BrownsMitch Goldich: BrownsMike Kadlick: BrownsGilberto Manzano: JetsConor Orr: BrownsJohn Pluym: BrownsMatt Verderame: BrownsColts at SteelersAlbert Breer: ColtsEva Geitheim: SteelersMitch Goldich: SteelersMike Kadlick: SteelersGilberto Manzano: ColtsConor Orr: ColtsJohn Pluym: ColtsMatt Verderame: SteelersGiants at CommandersAlbert Breer: GiantsEva Geitheim: CommandersMitch Goldich: GiantsMike Kadlick: GiantsGilberto Manzano: GiantsConor Orr: CommandersJohn Pluym: GiantsMatt Verderame: CommandersBroncos at ChargersAlbert Breer: BroncosEva Geitheim: BroncosMitch Goldich: ChargersMike Kadlick: ChargersGilberto Manzano: BroncosConor Orr: BroncosJohn Pluym: BroncosMatt Verderame: ChargersLions at CardinalsAlbert Breer: LionsEva Geitheim: CardinalsMitch Goldich: CardinalsMike Kadlick: CardinalsGilberto Manzano: LionsConor Orr: LionsJohn Pluym: LionsMatt Verderame: Lions49ers at SeahawksAlbert Breer: SeahawksEva Geitheim: 49ersMitch Goldich: SeahawksMike Kadlick: 49ersGilberto Manzano: 49ersConor Orr: SeahawksJohn Pluym: SeahawksMatt Verderame: SeahawksRavens at FalconsAlbert Breer: RavensEva Geitheim: FalconsMitch Goldich: FalconsMike Kadlick: FalconsGilberto Manzano: FalconsConor Orr: FalconsJohn Pluym: FalconsMatt Verderame: FalconsBills at RamsAlbert Breer: BillsEva Geitheim: BillsMitch Goldich: BillsMike Kadlick: RamsGilberto Manzano: RamsConor Orr: RamsJohn Pluym: RamsMatt Verderame: RamsAdd us as a preferred source on GoogleFollow