49ers vs. Panthers Preview, Injury News, Prediction, Keys To The Game For NFL Week 12 On MNF

49ers vs. Panthers Preview, Injury News, Prediction, Keys To The Game For NFL Week 12 On MNF

[Music] This is the San Francisco 49ers report. My name is Chase Senior. Coming up here on the show, I’m going to preview this Monday night football game in week 12 at Levi Stadium between the 49ers and the Carolina Panthers. San Francisco in this game. I was shocked when I saw this line. touchdown favorites, giving seven points to Carolina. And the overunder is even pretty high. 49 a half. Kickoff set for 8:15 p.m. Eastern, 5:15 p.m. Pacific at Levi Stadium in Santa Clara. And you already know, we’ll be live for a watch party right here on the Niners Report. The best place to experience a Niners game day outside of being at the actual game. We’ll go live for a pregame show. We’ll be live during the game. live playbyplay, audience interaction, super chat, giveaways. We’ll take down some beers and then after the game, we’ll be live and react to everything with our postgame show. My initial thoughts on this matchup, the Carolina Panthers are a feisty team. You might hear Carolina Panthers and say, “Oh, of late sucked.” This year they suck. They’ve won six games this season. Dave Canales, really good head coach, really made a name for himself being Baker Mayfield’s offensive coordinator a couple of years ago. And while Bryce Young played well at the back half of last year, hasn’t really played well this year. Dave Canales, if you get him a quarterback, I think that he can be one of the top coaches in the NFL. When you look at some of the Panthers numbers, they can’t get after the quarterback. Bryce Young has not been good this season. It’s pretty wild that they have won six games this season. That comes down to high quality coaching. This team being ready, making some adjustments, and obviously quality coaching, maximizing the current players on this roster. The ners huge favorites in this game. I think given what they did against the Cardinals and how well the offense played with Brock Pury being back, Ricky Pearaw being healthy, George KD rounding into form that went into the Ner being favored by a touchdown in this game and a big storyline here on Monday night that I’ll be watching closely. Can this Ner’s offense with what they did against Arizona continue its momentum? because I’ve said this a lot here on this show. This defense is going to struggle. This Niners defense, like Carolina, can’t get after the quarterback. So, this offense is going to have to carry this squad and they’re going to have to hover around 30 points per game to make up for this defense not being that good. The Panthers thus far this season started off 0 and2 and you’re thinking, “Yeah, Panthers, bad football team. They’re going to pick in the top five in the 2026 draft.” They’ve really turned it around. They lost week one 26-10 on the road to the Jags. Week two lost to the Cardinals 27-22. They come home for their home opener and they dust the Atlanta Falcons. Shut out 30 to nothing win. They lose against the Patriots 42-13. They hold off by three against the Dolphins in a game where they came back and had no business winning 2724. The Panthers at home beat the Dallas Cowboys 30 to 27. Rico Dattle ran crazy against his former team. Edged the Jets 13-6, one of the more more exciting games of the year. Sarcastic 40 to9 loss against the Buffalo Bills. Beat the Packers at the buzzer on a game-winning field goal 1613. Then they come back off of that huge win and lose to the Saints 17-7. And then they sweep the Falcons and beat Atlanta for a second time this year 30-27 in overtime. So an up and down weird year for Carolina. At times they’ve looked good. At times they’ve looked bad, but when it comes down to it, it’s not like they’ve beaten a bunch of great teams, but they’ve won six games this year. And a lot of people didn’t think that they could get to that. And here we are entering week 12. So, when I scout Carolina, this is one of the worst pass rushing units in the National Football League, right down there with the NerS. Bryce Young has not been good. But this offense runs through and leans on running back Rico Dattle, who had a career year last year with Dallas. And this year has been one of the top backs in football. And I’m just telling you right now, I saw what Dave Canales did in 2023 with Baker Mayfield when Baker resurrected his career. If he gets a quality quarterback, this Panthers team in the NFC, given how bad the NFC South is, could be a playoff team before it’s said and done and a playoff team very quickly. And shoot, this year they’re vying to be a playoff team. Some injury news on both sidelines here for Carolina. Wide receiver Xavier Legette hip injury. questionable. Linebacker Christian Roseboom, hamstring, questionable. Xavier Legette, a bigbodied wide receiver, is expected to play in this game. On the injury front for the Niners early in the year, this was literally a couple of different pages. As I record this show on Thursday, November 20th, these are the Niners notable injuries. Tatum Mthune will not play, high ankle sprain. Eddie Panera will not play. Hamstring strain. Grade one. Robert Beal, edge rusher in concussion protocol. I never liked the decision for the Niners to activate him instead of Cleveland Furl. We’ll see what the Niners do at that edge rusher spot. I would opt with Furl because I think he’s a better player. Speaking of Eddie Pinera, the Niners making a roster move this week on Wednesday. They did sign kicker Matt Gay. won a Super Bowl with the Rams back in 2021 and was great that year. He was a Pro Bowler with the Rams as well. Last two years with the Colts and with the Commanders, he struggled a little bit. Not on extra points. He’s 100% on extra points the last two years, but on kicks of 50 plus, he has missed his mark. This season with Washington, funny enough, he was let go and then the Commanders signed Jake Moody. Two of two on kicks of 20 to 29 yards. 30-39 two of three. Five of five on kicks of 40 to 49 yards, but only four of nine on kicks of 50 plus. Eddie Pierro 22 for 22 on his field goals this year. Incredibly clutch. All Matt Gay has to do is hold the water until Eddie Piner is able to come back. So, who you got in this football game? C A R for Carolina, SF for the 49ers. Get those predictions in right now. Coming up next, we’re about to get into the meat and potatoes of our preview, my keys to the game, top matchups to watch, what the NerS must do to beat Carolina on Monday night. Stay tuned for all of that. But let’s first get to our sponsor, our friends at Harry’s making today’s 49ers report possible. We have a great deal. Check it out for yourself at harry’s.com. And for all my fellas out there, when using a razor, does it get dull too fast? Does it irritate your neck? 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Coming up, my keys to the game for this Monday Night Football game between the Niners and the Panthers. I’m going to give you my prediction as well. Top matchups to watch. We’ll break that down and what the Niners must do in order to be victorious to move that record to 8 and4 on the year. how the Panthers stack up on offense. Carolina 18-8 points per game, 28th in the NFL, 314.3 yards per game, that’s 22nd. Five yards per play, 26th. Third down conversion rate 36.9%. That’s 24th. Their red zone touchdown scoring rate 54.2% 20th in the NFL. on defense, 22.6 points per game allowed. 13th, 325.9 yards per game surrendered. 15th, 5.6 yards per play. That’s 23rd. Their third down conversion rate, 43.3%. That’s 29th in the NFL. So, the Niners going to have an opportunity here to move the chains. And then their red zone touchdown scoring percentage is top 10 as a defense. number nine there at 52.9%. As for how the NerS stack up on offense, 15th in points per game at 23.7, 10th in yards per game, they’ve been moving it at 349.4, 13th in yards per play at 5.5. Third down conversion rate, third best in the NFL at 45.6%. 62.5% is their red zone touchdown scoring rate. that has gotten higher, especially after what the NerS did against the Cardinals last week. And then you look at the defense, 22.9 points per game. That’s 15th in the NFL. To be there with all these injuries and young players playing, hat tip to Robert Salah. 25th in yards per game. That’s fine when you’re not giving up a lot of points and buckling down in the red area. 25th in yards per play at 5.7. Third Doug conversion rate 40.7%. It’s 22nd best in the NFL and their red zone scoring percentage 16th 58.9%. So my keys to the game for the ners to be victorious here, some of my top matchups to watch, I’ll tell you this, the pass rushing units for the Niners and the Panthers absolutely stink. If you are somebody who loves watching dominant pass rushes and watching teams hunt and get after the quarterback, this game is not for you because these pass rushers have really struggled to get pressure on the opposing QB. The Niners this year total sacks, they only have 12. It’s 32nd in the NFL. Their second best sack producer is Nick Bosa. He hasn’t played since week three. Total pressure is 107. 26th in the NFL. The Niners have 79 hurries. It’s 29th in the league. Their pressure rate dead last at 26.23%. The Panthers pass rushing stats not much better. Total sacks 16th. Total pressures 142. That ranks 30th. Total hurries 90. That’s 25th. Their pressure rate just north of 38%. That’s second to last in the NFL. So Bryce Young, Brock Pury, these are numbers that you like to see because that means usually you will have a clean pocket. Another thing with the NerS, intermediate to long passes since Fred Warner has gotten hurt, they’ve been one of the worst defenses in the NFL, giving up a lot of explosive plays. Bryce Young hasn’t been able to really find it all year long. Has an opportunity to find it against the NerS here. Key to the game number two. This Panthers offense runs through Rico Dael. And I was surprised that the Cowboys let Rico Dowel go. They needed a running back. Now they’ve replaced him with a running back who has ended up performing pretty well. And I guess it’s worked out for both parties. But for Carolina, Rico Dout’s been awesome. Javvante Williams with Dallas, he’s been good, but I think Rico Dout’s been better. And you look at the rushing yards leaders in 2025. Nobody outside of Jonathan Taylor had this list looking like this going into week 12. And with running backs, so much can change year-over-year, of course. Now, Jonathan Taylor is leading the NFL in rushing yards at 1,139. James Cook is a stellar back. I didn’t expect him to be number two this year, 968. Devon Achan, 900 yards. He’s number three. Rico Dattle, fourth leading rusher in the NFL with 833 rushing yards this season. And then Javvante Williams there at 89. The aforementioned Javvante Williams of the Dallas Cowboys. Rico this year has had some splash games for the most part. This Niners rushing defense has improved from last year against the Rams. They were not good. And without Mel Williams, I think that’s an area where they could continue to struggle because Mel Williams is such an excellent run defender. But data this year, if you don’t bring it as far as your rush defense, he’ll make you pay. Back on October 5th against Miami, 23 totes for 206 yards, nine yards per carry against the Cowboys a little over a month ago, 30 carries for a buck 83, 6.1 yards per carry against the Packers back a couple of weeks ago, earlier this month, 25 carries, 130 yards, and 5.2 yards per carry. That is a big reason why the Panthers have been able to find success with what they’re doing in a ground game. They’ve had to rely on running the football because Bryce Young has been not good this year. Not going to say terrible, just hasn’t been that good. He’s completing under 63% of his passes. He’s thrown for less than 2,000 yards, 14 touchdowns, seven picks. He just looks small, can’t really drive the ball, doesn’t move around, doesn’t see the field all that well. Now, what Niners’s defense are we going to get? This is a Niners defense that did give up 488 yards last week to Jacobe Brassette and the Cardinals. 6.9 yards per play. Jacobe Brassette dropped back 57 times. The Niners only pressured him 13 times. Did not have a single sack. They gave up 452 passing yards. the bright spot of that Ner’s performance, the improvements against the run, which in the week prior against the Rams, it killed him because the Rams were able to control the game. That’s what happens when you’re able to run the ball successfully and on defense when you can’t stop the run. So, 14 carries for 36 yards, 2.6 yards per pop. I imagine the Niners are going to sell out in trying to stop Rico Dattle knowing they can’t allow the Panthers to get that ground game going knowing that Bryce Young throwing it this year has had some issues. Now the Sners rushing defense all year, yeah, not bad. 13th in yards per rush at 4.1, 12th in rushes per game. So teams are running at a decent amount. 25 running attempts per game. Rushing yards per game total 103.8. That’s 12 in the NFL. Key to the game number three, the Sner secondary has to bring it against T McMillan because the Carolina Panthers found a guy in T McMillan. The rookie first round pick out of Arizona, 6’4, well over 200 lb, runs well, can go up and get it. strong arms, long frame, good wingspan, and he’s going to be the number one wide receiver for this Panthers team for the foreseeable future. If Xavier Legette can get it together, he’s been bad for the most part, but played well last week. That is a very physically imposing onetwo punch at wide receiver for Carolina in his rookie season. and T McMillan 54 catches 748 yards 13.9 yards per catch four receiving touchdowns 68 yards per game something that I’ll be watching too in this game how will Brock Pury look against Carolina because against Arizona he was efficient he threw with really good touch he threw with accuracy in his patented rock pretty way he was able to layer the football I thought he moved round pretty well. He threw some balls up for grabs, but for him to have not played since week four, and to only have seven incompletions, throw for 200 yards, have a quarterback rating of 133.5, three touchdowns, no picks, and 10.5 was the number for the yards per completion. I was very pleased with how pretty played because he really wasn’t that rusty and didn’t really have to get his feet wet. I mean, he jumped right in and on his second drive, he was what, four of five for 68 yards and a 30- yard strike to George KD. We saw Brock Pretty coming back, brought about that George KD connection. He was dominant in that game. And then Christian McCaffrey running it, receiving it. He was also really good. I do have a prediction for this Panthers game. Breakout performer on Monday Night Football, it’s going to be Ricky Piolaw. thing. Ricky Pieraw didn’t put up a lot of numbers against Arizona last week, but if you go back and look at the tape, he got open a lot and there was some meat left in the bone for the Sners passing game. And at times, even when he was open, the pass rush kind of blew up the play and got to Brock Pur. But there were times where Ricky Pierce was able to separate. He was able to win. He was able to run filthier routes, juke out the DBs, and he was open. We have seen that Pertas had a good connection with Ricky Pearl and against this Panther secondary, which is okay. Not bad, not great. I think that Piersaw has a big game in prime time on Monday night. And this is an important development for the Niners here overtime. And what’s happened recently, this Niners offensive line has improved. Now, when the Niners offensive line goes up against legitimate defenses and really good edge rushers and fronts, that’s when they struggle. When they go up against bad teams, that’s when they’re able to have their way. But even when they go up against good teams, there are some positive developments here for this Niners offensive line. They have stabilized the left guard position with this veteran tandem after benching Connor Kby. Spencer Berford, Ben Bart have been rotating there at left guard and they’ve been playing pretty well. And then another big development here is that Dominic Puny is healthy and he’s playing well. Early in the year that knee was not right from when he got injured against the Raiders in that preseason game. He struggled mightily. Now that he’s gotten healthy, he’s strong enough with the anchor, the physicality, and the athleticism is back. He’s able to get a push, and he looks a lot more like the player who we saw last year who is one of the top guards in all of football. So, uh, predict the score for me. Carolina Panther, San Francisco 49ers. Always want you to join the conversation down in the comment section. The Niners are sevenpoint favorites in this football game and I think this Niners offense continues to hum a little bit with what they did against the Cardinals with them getting healthier and acclimated with one another that rapport working a little bit. So, give me the Niners 3120. And I know that from team value, Niners Panthers doesn’t get doesn’t get a lot of people juice as far as this Monday Night Football game, especially with Carolina. Smaller market, not a team that has a lot of stars. But as far as the playoff picture goes, this game has a lot of big implications here. The Niners are in that seven seed at seven and four. Not a lot of breathing room there. And the NFC North, it’s a really good competition right now. Three teams might get in. And if three teams get in, three teams from the NFC West not going to get in because you’re going to have to have your divisional winners from the NFC East. It’s going to be Philly and the NFC South. We’ll see between Tampa Bay and Carolina. But you look at where Carolina is. If the Niners lose this game and drop to seven and five, they have an equal record to Carolina and Carolina would own the tiebreaker. So, a big game in the NFC playoff hunt coming up on Monday night. Don’t forget to hit that subscribe button here for daily and yearround coverage of the San Francisco 49ers. As always, thank you so much for your support and we’ll catch you all soon. [Music]

49ers vs. Panthers preview going into the NFL week 12 schedule. Our San Francisco 49ers vs. Carolina Panthers preview will breakdown keys to the game, matchups to watch, betting odds, 49ers news, 49ers rumors, Panthers news, Panthers rumors and more.

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San Francisco 49ers Defensive Coaching Staff:
– Defensive Coordinator: Robert Saleh
– Assistant Head Coach of Defense: Gus Bradley
– Defensive Quality Control Coach: Cameron Brown
– Defensive Backs/Cornerbacks Coach: Ray Brown
– Defensive Passing Game Specialist/Defensive Backs Coach: Daniel Bullocks
– Linebackers Coach: Johnny Holland
– Defensive Line Coach: Kris Kocurek
– Defensive Quality Control Coach: Jake Lynch
– Assistant Defensive Line Coach: Greg Scruggs
– Defensive Quality Control Coach: KJ Wright

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