The St. Louis Cardinals (37-34) visit the Milwaukee Brewers (38-34) Sunday in the finale of a 4-game series. First pitch from American Family Field is set for 2:10 p.m. ET. Let’s analyze BetMGM Sportsbook’s MLB odds around the Cardinals vs. Brewers odds and make our expert MLB picks and predictions for the best bets.

Season series: Brewers lead 3-2

The Cardinals snapped their 6-game losing streak Saturday by beating the Brewers 8-5 as a +118 underdog. 2B Nolan Gorman led the way with 3 RBIs. St. Louis desperately needed that offensive performance as it had scored more than 4 runs just once in its previous 7 games before Saturday. St. Louis is 38-32 against the spread (ATS) on the season.

The Brewers, who sit second in the NL Central, have won 3 of their last 5 games and beat Cardinals a combined 9-2 in the first 2 games of the series. Milwaukee has played 3 straight series at home and has gone 4-5 in those contests. It is 13-6 over its last 19 games and is 36-35 ATS.

Cardinals at Brewers projected starters

RHP Miles Mikolas vs. RHP Quinn Priester

Mikolas (4-3, 4.48 ERA) makes his 14th start. He has a 1.31 WHIP, 2.3 BB/9 and 5.2 K/9 through 66 1/3 innings.

Last start: Loss, 5 IP, 6 ER, 9 H, 0 BB, 2 K in 10-9 home loss vs. Toronto Blue Jays last Tuesday2025 road stats: 3-1, 3.97 ERA (34 IP, 15 ER), 1 HR, 1.41 WHIP, 5.4 K/9 in 7 startsCareer vs. Brewers: 10-6, 3.87 ERA (111 2/3 IP, 48 ER), 1.02 WHIP, 7.8 K/9 in 18 starts and 1 relief appearance

Priester (4-2, 3.65 ERA) makes his 9th start and 13th appearance. He has a 1.30 WHIP, 3.8 BB/9 and 6.3 K/9 through 61 2/3 innings.

Last start: Win, 6 IP, 1 ER, 7 H, 0 BB, 7 K in 4-1 home victory vs. Atlanta Braves last Tuesday2025 home stats: 2-1, 4.21 ERA (25 2/3 IP, 12 ER), 3 HR, 1.25 WHIP, 7.0 K/9 in 3 starts and 2 relief appearancesCareer vs. Cardinals: 0-0, 9.00 ERA (5 IP, 5 ER), 2.20 WHIP, 8 H, 2 K in 1 start, a 6-5 road loss on April 21, 2025

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Cardinals at Brewers odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Saturday at 10:51 p.m. ET.

Moneyline (ML): Cardinals +105 (bet $100 to win $105) | Brewers -125 (bet $125 to win $100)Run line (RL)/Against the spread (ATS): Cardinals +1.5 (-200) | Brewers -1.5 (+165)Over/Under (O/U): 8.5 (O: +100 | U: -120)Cardinals at Brewers picks and predictionsPrediction

Brewers 4, Cardinals 3

BET BREWERS (-125).

The Brewers have been dominant as a home favorite this season, going 16-7 on the moneyline in that position. Milwaukee has allowed just 5 runs in Priester’s last 3 starts as well, so he has limited opponents as of late.

The Cardinals have dropped 4 of their last 6 road games and have struggled defensively, allowing 5 or more runs in 6 of their last 7 contests. Considering those trends, take BREWERS (-125).

PASS.

There’s no playable run line wager. The Brewers (+165) are too risky while the Cardinals (-200) are far too expensive to consider here as well. Avoid this play and look to the moneyline for a team-specific wager.

BET UNDER 8.5 (-120).

With both teams having a quality starting option, the Under is the better play. Milwaukee has gone Under in Priester’s last 3 starts and is 26-42-3 O/U on the season. It is 3-6 O/U in its last 9 at home.

Mikolas is 3-3 O/U in his last 6 starts while the Cardinals have gone Under in 3 of their last 4. Play UNDER 8.5 (-120).

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