SEATTLE — The Guardians came into their weekend series against the Mariners looking to remain in contention in the American League Central Division, but instead limped out of town Sunday after being swept by a Seattle squad that had lost five of its previous six games.

The Mariners scored five runs in the second inning against Cleveland starter Luis Ortiz, highlighted by J.P. Crawford’s fifth career grand slam, and handed the lifeless Guardians a 6-0 loss at T-Mobile Park.

Mariners right-hander Emerson Hancock, meanwhile, picked up his third win by shutting down Cleveland’s offense, limiting the Guardians to just two hits over seven innings while walking one and striking out four. Hancock (3-2) allowed a two-out single to Lane Thomas in the second inning and a leadoff base hit to Angel Martínez in the third, but went on to retire the final 14 batters he faced.

Ortiz walked Randy Arozarena to open the second before Rowdy Tellez doubled and Dominic Canzone drew a walk to load the bases. Miles Mastrobuoni’s RBI single to right scored Arozarena to give Seattle a 1-0 lead and bring Crawford to the plate.

Crawford entered the game batting .261 with a home run and 13 RBI in 28 career games against Cleveland, but was 6 for 8 with a double and an RBI in the first two games of the series. He fell behind Ortiz early in the count, before picking out a slider low and over the middle of the plate that he launched 377 feet into the right field seats for his sixth home run.

Ortiz (3-8) settled in after that, working through the sixth and finishing with five strikeouts, five walks and five hits allowed. He walked Arozarena with one out in the fifth, and allowed an RBI single to Mitch Garver after Arozarena picked up his second stolen base of the day.

The only drama of the afternoon for Cleveland was seeing whether or not José Ramírez could extend his career-high on-base streak. With Ramírez hitless in three trips to the plate and two out in the ninth, Kyle Manzardo bounced a single up the middle against Seattle reliever Eduard Bazardo. But Ramírez grounded out to second to end the game, halting his streak one game short of becoming the first Cleveland player to reach in 40 straight since Jim Thome in 2002.

All-Star left fielder Steven Kwan left the game in the sixth inning. Afterward, Vogt said that Kwan got jammed on a pitch in the third inning and he took him out of the game despite Kwan’s own protest.

Kwan was replaced by Johnathan Rodríguez. Kwan left Cleveland’s game against the Dodgers on May 28 after experiencing soreness in his right wrist, but was back in the lineup against the Angels after an off day and did not miss a start.

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The Guardians are off Monday before opening a three-game series in San Francisco on Tuesday. Neither team has announced a starting pitcher for Tuesday’s game, which is slated to start at 9:45 p.m. ET. CLEGuardians.TV, WTAM 1100 AM, WMMS 100.7 FM and the Guardians Radio Network will carry the contest.