The Baltimore Orioles (43-52) and the Tampa Bay Rays (50-47) open a 3-game series Friday. First pitch from George M. Steinbrenner Field is scheduled for 7:35 p.m. ET. Let’s analyze BetMGM Sportsbook’s MLB odds around the Orioles vs. Rays odds and make our expert MLB picks and predictions for the best bets.

Season series: Orioles lead 4-3

The Orioles lost 2 of 3 games to the Miami Marlins in Baltimore before the All-Star break. They wrapped up the set with an 11-1 loss as -143 favorites Sunday with the Over (9) cashing. RF Ramón Laureano launched a solo shot in the eighth inning, his first of the month after hitting 4 homers in June.

The Rays were swept in 4 games at the Boston Red Sox before the break. They dropped each of the first 3 games by just a single run, but lost 4-1 as +103 underdogs in Sunday’s finale with the Under (8.5) hitting. RF Josh Lowe drove in Tampa Bay’s lone run Sunday on a sacrifice fly in the fourth inning.

Orioles at Rays projected starters

RHP Charlie Morton vs. RHP Taj Bradley

Morton (5-7, 5.18 ERA) makes his 15th start and 21st appearance. He has a 1.52 WHIP, 4.1 BB/9 and 9.5 K/9 through 83 1/3 innings.

Last start: No-decision, 6 IP, 1 ER, 4 H, 3 BB, 4 K in 3-1 home victory vs. New York Mets July 102025 road stats: 2-4, 5.97 ERA (31 2/3 IP, 21 ER), 1.67 WHIP, 9.4 K/9 in 6 starts and 2 relief appearances2025 vs. Rays: 1 road start (June 19), win, 6 IP, 1 ER, 6 H, 0 BB, 7 K in 4-1 victoryCareer vs. Rays: 5-3, 2.78 ERA (55 IP, 17 ER), 1.09 WHIP, 10.8 K/9 in 9 starts

Bradley (5-6, 4.60 ERA) makes his 20th start. He has a 1.27 WHIP, 3.5 BB/9 and 7.7 K/9 through 103 2/3 innings.

Last start: No-decision, 6 IP, 1 ER, 2 H, 3 BB, 5 K in 4-3 setback at Red Sox July 102025 home stats: 3-3, 5.55 ERA (48 2/3 IP, 30 ER), 1.34 WHIP, 7.6 K/9 in 9 starts2025 vs. Orioles: 0-1, 14.85 ERA (6 2/3 IP, 11 ER), 2.40 WHIP, 14 H, 2 BB, 4 K in 2 startsCareer vs. Orioles: 1-3, 8.65 ERA (26 IP, 25 ER), 1.58 WHIP, 9.7 K/9 in 6 starts

Win your fantasy baseball league with BaseballHQ.com. For decades, BHQ has been helping players just like you win! BHQ offers full-season subscriptions. Sign up today and start winning!

Orioles at Rays odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Thursday at 8:31 p.m. ET.

Moneyline (ML): Orioles +100 (bet $100 to win $100) | Rays -120 (bet $120 to win $100)Run line (RL)/Against the spread (ATS): Orioles -1.5 (+155) | Rays +1.5 (-190)Over/Under (O/U): 9 (O: -110 | U: -110)Orioles at Rays picks and predictionsPrediction

Orioles 4, Rays 3

BALTIMORE (+100) has won 6 of its last 9 games and has a decent shot at upsetting Tampa Bay, which has lost 11 of its last 14 games.

Bradley is 1-3 with an 8.65 ERA in 6 career starts vs. the Orioles, while Morton held the Rays to just 1 run in 6 innings in their June 19 meeting. The Rays are the better team overall, but Bradley can’t be trusted vs. Baltimore — especially at this price.

BET ORIOLES (+100).

While Baltimore has gone 6-3 over its last 9 games, 31 of its last 37 losses have been by multiple runs.

PASS on the run line.

Tampa Bay has scored 4 or fewer runs in 6 of its last 7 games, with the Under going 5-1-1 during that stretch.

Meanwhile, even though Baltimore has tagged Bradley for 11 ER in 6 2/3 innings across 2 starts this year, it scored just a single run over its last 2 games before the break. The Orioles offense will likely bounce back Friday, but this number is a bit too high.

BET UNDER 9 (-110).

Play our free daily Pick’em Challenge and win! Play now!

For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

Follow @corey_a_scott on Twitter/X. Follow SportsbookWire on Twitter/X and like us on Facebook.