The Washington Nationals (41-61) will visit the Minnesota Twins (49-53), Friday at 8:10 p.m. ET, in the first game of a three-game series.

The Twins are favored (-144 on the moneyline) when they host the Nationals (+122). The Twins will give the ball to Zebby Matthews (1-2) against the Nationals and MacKenzie Gore (4-9).

The Twins lost 4-3 against the Dodgers Wednesday, with Griffin Jax taking the loss. He threw 2/3 of an inning, giving up two earned runs on two hits. Royce Lewis went 2 for 2 with a double, a home run and an RBI to lead the Twins offensively.

The Nationals lost to the Reds Wednesday, with Mike Soroka registering the loss while pitching 5 2/3 innings, giving up one earned run on two hits while striking out six. Amed Rosario went 1 for 4 to lead the Nationals’ offense.

Ahead of watching this Twins vs. Nationals matchup, here’s what you need to know about Friday’s action on the diamond, including viewing options.

Minnesota Twins vs. Washington Nationals odds, line and spread

MLB odds courtesy of BetMGM Sportsbook. Odds updated Thursday at 3:16 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.

Favorite: Twins (-144, bet $144 to win $100)Underdog: Nationals (+122, bet $100 to win $122)Over/under: 8.5Twins vs. Nationals: Game time and live stream infoGame day: Friday, July 25, 2025Game time: 8:10 p.m. ETLocation: Minneapolis, MinnesotaStadium: Target FieldTV channel: MLB Network, MNNT, and MASN2Live stream: Watch LIVE with Fubo! (Regional restrictions may apply)

Watch Twins vs. Nationals on Fubo!

Twins stats and trendsTwins betting recordsThis season, the Twins have been favored 65 times and won 34, or 52.3%, of those games.Minnesota has a record of 16-9, a 64% win rate, when favored by -144 or more by bookmakers this season.Oddsmakers have implied with the moneyline set for this matchup that the Twins have a 59% chance to win.Minnesota and its opponents have gone over the total this season in 41 of 101 opportunities.The Twins have an ATS record of 54-47-0 in 101 games with a spread this season.Zebby Matthews (Twins probable starter)Matthews gets the start for the Twins, his sixth of the season. He is 1-2 with a 6.26 ERA and 31 strikeouts in 23 2/3 innings pitched.His most recent time out was on Sunday against the Colorado Rockies, when the right-hander tossed four innings, surrendering five earned runs while allowing eight hits.The 25-year-old has put up an ERA of 6.26, with 12.1 strikeouts per nine innings, in five games this season. Opponents are batting .298 against him.So far this season, Matthews does not have a quality start.Matthews has put up two starts this year in which he pitched five or more innings.He has allowed one or more earned runs in all of his appearances.The opposing Nationals offense has the 20th-ranked slugging percentage (.389) and is 22nd in MLB play with 99 home runs. It has a collective .245 batting average, and is 18th in MLB with 839 total hits and 17th in MLB play scoring 440 runs.Twins batting statsThe Twins rank 11th in Major League Baseball with 120 home runs.Fueled by 294 extra-base hits, Minnesota ranks 15th in MLB with a .401 slugging percentage this season.The Twins’ .242 batting average ranks 21st in the league this season.Minnesota has scored 434 runs (4.3 per game) this season, which ranks 19th in MLB.The Twins have the 20th-ranked on-base percentage in MLB this season (.312).Minnesota ranks 14th with an average of 8.3 strikeouts per game.Nationals stats and trendsNationals betting recordsThe Nationals have been chosen as underdogs in 86 games this year and have walked away with the win 37 times (43%) in those games.Washington has a win-loss record of 19-34 when favored by +122 or worse by oddsmakers this year.The moneyline set for this matchup implies the Nationals have a 45% chance of coming away with a victory in the contest.Washington and its opponents have gone over the total this season in 52 of its 101 opportunities.The Nationals are 51-50-0 against the spread in their 101 games that had a posted line this season.MacKenzie Gore (Nationals probable starter)The Nationals will send Gore (4-9) to make his 21st start of the season. He is 4-9 with a 3.59 ERA and 140 strikeouts in 112 2/3 innings pitched.In his most recent appearance on Sunday against the San Diego Padres, the lefty threw 2 1/3 innings, allowing eight earned runs while surrendering eight hits.The 26-year-old has amassed an ERA of 3.59, with 11.2 strikeouts per nine innings in 20 games this season. Opponents are batting .247 against him.Gore has recorded 12 quality starts this season.Gore has put up 18 starts this year that he pitched five or more innings.He has had three appearances this season in which he did not surrender an earned run.The opposing Twins offense has a collective .242 batting average, and is 22nd in the league with 825 total hits and 19th in MLB play with 434 runs scored. They have the 15th-ranked slugging percentage (.401) and are 11th in all of MLB with 120 home runs.The 26-year-old ranks 31st in ERA (3.59), 40th in WHIP (1.269), and fifth in K/9 (11.2) among qualifying pitchers in MLB play this season.Nationals batting statsThe Nationals average 1.0 home run per game to rank 22nd in MLB play with 99 total home runs.So far this year, Washington is 20th in baseball, slugging .389.The Nationals are 17th in MLB with a .245 batting average.Washington scores the 17th-most runs in baseball (440 total, 4.3 per game).The Nationals rank 21st in the majors with an on-base percentage of .311.

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