On Saturday, a series opener is on the schedule, with the Washington Nationals (41-61) visiting the Minnesota Twins (49-53) at 7:10 p.m. ET.

The Twins are a home favorite (-164) against the Nationals (+138). The Minnesota Twins will hand the ball to Joe Ryan (10-4, 2.63 ERA), who is looking for win No. 11 on the season, and the Nationals will turn to Mitchell Parker (6-10, 5.08 ERA).

The Twins’ matchup Wednesday versus the Dodgers resulted in a 4-3 loss. Royce Lewis went 2 for 2 with a double, a home run and an RBI in the defeat, while Griffin Jax threw 2/3 of an inning, giving up two earned runs on two hits en route to taking the loss.

Wednesday, the Nationals fell to the Reds 5-0. Mike Soroka was the losing pitcher after he went 5 2/3 innings, giving up one earned run on two hits while striking out six. Amed Rosario led the Nationals’ offense, going 1 for 4.

Prepare for the Twins vs. Nationals with everything you need to know before Saturday’s game, including viewing options.

Minnesota Twins vs. Washington Nationals odds, line and spread

MLB odds courtesy of BetMGM Sportsbook. Odds updated Friday at 9:20 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.

Favorite: Twins (-164, bet $164 to win $100)Underdog: Nationals (+138, bet $100 to win $138)Over/under: 8.5Twins vs. Nationals: Game time and live stream infoGame day: Saturday, July 26, 2025Game time: 7:10 p.m. ETLocation: Minneapolis, MinnesotaStadium: Target FieldTV channel: MNNT and MASN2Live stream: Watch LIVE with Fubo! (Regional restrictions may apply)

Watch Twins vs. Nationals on Fubo!

Twins stats and trendsTwins betting recordsThe Twins have won 34, or 52.3%, of the 65 games they’ve played as favorites this season.Minnesota is 12-6 this season when entering a game favored by -164 or more on the moneyline.Sportsbooks have implied with the moneyline set for this matchup that the Twins have a 62.1% chance to win.Minnesota and its opponents have gone over the total this season in 41 of 101 opportunities.The Twins are 54-47-0 against the spread in their 101 chances this season.Joe Ryan (Twins probable starter)Ryan (10-4 with a 2.63 ERA and 132 strikeouts in 116 1/3 innings pitched) makes the start for the Twins, his 20th of the season.In his most recent appearance on Sunday against the Colorado Rockies, the right-hander tossed seven innings, giving up one earned run while surrendering five hits.The 29-year-old has a 2.63 ERA and 10.2 strikeouts per nine innings across 20 games this season, while giving up a batting average of .197 to his opponents.Ryan has 11 quality starts under his belt this year.Ryan will aim to go five or more innings for his 21st straight appearance. He’s averaging 5.8 frames per outing.In four of his appearances this season he did not allow an earned run.The opposing Nationals offense has a collective .245 batting average, and is 19th in the league with 839 total hits and 18th in MLB play with 440 runs scored. It has the 20th-ranked slugging percentage (.389) and ranks 22nd in home runs (99) in all of MLB.Among pitchers who qualify in MLB action this season, the 29-year-old ranks 12th in ERA (2.63), fourth in WHIP (.903), and eighth in K/9 (10.2).Twins batting statsThe Twins have hit 120 homers this season, which ranks 11th in the league.Fueled by 294 extra-base hits, Minnesota ranks 15th in MLB with a .401 slugging percentage this season.The Twins have a team batting average of .242 this season, which ranks 21st among MLB teams.Minnesota ranks 20th in the majors with 434 total runs scored this season.The Twins have an OBP of .312 this season, which ranks 20th in MLB.Minnesota ranks 14th in MLB in strikeouts per game with an average of 8.3 whiffs per contest.Nationals stats and trendsNationals betting recordsThe Nationals have won in 37, or 43%, of the 86 contests they have been named as odds-on underdogs this year.This year, Washington has won 15 of 39 games when listed as at least +138 or worse on the moneyline.The moneyline set for this matchup implies the Nationals have a 42% chance of coming away with a victory in the contest.Washington and its opponents have gone over the total this season in 52 of its 101 opportunities.The Nationals have an against the spread record of 51-50-0 in 101 games with a line this season.Mitchell Parker (Nationals probable starter)Parker makes the start for the Nationals, his 21st of the season. He is 6-10 with a 5.08 ERA and 70 strikeouts in 108 2/3 innings pitched.His most recent appearance came on Saturday against the San Diego Padres, when the left-hander went six innings, surrendering two earned runs while giving up five hits.The 25-year-old has put up an ERA of 5.08, with 5.8 strikeouts per nine innings in 20 games this season. Opponents have a .260 batting average against him.Parker has nine quality starts this year.Parker is looking to collect his 15th start of five or more innings this season in this game.He has had two appearances this season that he held his opponents to zero earned runs.He will match up with a Twins offense that is batting .242 as a unit (21st in the MLB). They are also slugging a collective .401 (15th in the league) with 120 total home runs (11th in MLB action).Among qualifying pitchers in MLB play this season, the 25-year-old ranks 59th in ERA (5.08), 56th in WHIP (1.398), and 59th in K/9 (5.8).Nationals batting statsThe Nationals rank 22nd in baseball with 99 home runs. They average 1.0 per game.This season, Washington’s .389 slugging percentage ranks 20th in the majors.The Nationals are 18th in the majors with a .245 batting average.The offense for Washington is the No. 18 offense in baseball, scoring 4.3 runs per game (440 total runs).The Nationals are 21st in baseball with an on-base percentage of .311.

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