Alec Burleson and Ian Happ will be front and center on Friday night when the St. Louis Cardinals welcome the Chicago Cubs to Busch Stadium for the latest chapter in their long-standing rivalry.

The Cubs enter the weekend at 66-48, sitting second in the NL Central and still chasing the division-leading Brewers, who hold a four-game edge. Chicago currently controls the top Wild Card position, with a comfortable seven-game cushion over the Reds. The road has been relatively kind to them this year, as they’ve posted a 30-26 mark away from Wrigley Field.

St. Louis, meanwhile, comes in at 58-58, trying to claw its way back into contention. The Cardinals trail Milwaukee by 13 games in the division race and are 5.5 games shy of the Mets for the final NL Wild Card berth. Home cooking has been a bright spot, with the club sporting a 32-24 record at Busch.

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How to watch St. Louis Cardinals vs Chicago Cubs on TV & stream live onlineNational TV channel: MLBNLocal TV channel: FDSMW, and MARQStreaming service: Fubo

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St. Louis Cardinals will take on Chicago Cubs in a highly anticipated MLB game on Friday, August 8, 2025, at 7:05 pm ET/ 4:05 pm PT at Busch Stadium in St. Louis, Missouri.

DateFriday, August 8, 2025First-Pitch Time7:05 pm ET/ 4:05 pm PTVenueBusch StadiumLocationSt. Louis, MissouriStreaming the game with a VPN

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St. Louis Cardinals vs Chicago Cubs team newsSt. Louis Cardinals team news

The Cardinals counter with some strong bats of their own. Brendan Donovan leads the club with a .280 average, while Burleson is close behind at .279 with 19 doubles and 14 home runs. Willson Contreras holds the team lead in homers (16) and RBIs (64). Rookie Masyn Winn has been a spark, hitting .270 with 24 doubles and eight homers.

Right-hander Michael McGreevy will take the ball for St. Louis. In his six starts this season, he’s 3-2 with a 5.08 ERA, striking out 23 and walking six over 39.1 innings. While not overpowering, McGreevy thrives when he can induce soft contact and stay in the zone, though he’s struggled more at Busch than on the road, and July wasn’t his friend.

Chicago Cubs team news

For Chicago, Pete Crow-Armstrong has been a power machine, leading the club with 27 homers, good for seventh in all of baseball, and ranking ninth in RBIs. Seiya Suzuki has matched that home run total while pacing the team with 84 runs driven in. Nico Hoerner’s .292 batting average tops the roster. 

On the mound, lefty Matthew Boyd has been a steady hand in the rotation, going 11-4 with a 2.34 ERA over 22 starts. His 118 strikeouts against just 29 walks highlight his command, and while the occasional long ball has stung, he’s consistently pitched deep into games to keep the Cubs competitive.

St. Louis Cardinals vs Chicago Cubs projected starting pitchersDateCardinalsCubs08/07/2025Michael McGreevyMatthew BoydSt. Louis Cardinals vs Chicago Cubs head-to-head recordDateCompetitionHome TeamAway TeamScore07/07/25MLBChicago CubsSt.Louis Cardinals11 – 007/05/25MLBChicago CubsSt.Louis Cardinals6 – 807/04/25MLBChicago CubsSt.Louis Cardinals11 – 306/26/25MLBSt.Louis CardinalsChicago Cubs0 – 306/26/25MLBSt.Louis CardinalsChicago Cubs0 – 8More MLB news and coverage