The Detroit Tigers (72-52) and the Minnesota Twins (57-65) play the third game of a 4-game series Saturday. First pitch from Target Field is set for 7:15 p.m. ET (FOX). Let’s analyze BetMGM Sportsbook’s MLB odds around the Tigers vs. Twins odds and make our expert MLB picks and predictions for the best bets.

Season series: Tigers lead 4-1

Detroit jumped on Minnesota early with a 5-run first inning and rolled to a 7-0 win Friday, clinching the first 2 games of the series. The Tigers also won 4-3 Thursday and have taken 4 of their last 5, though they’re just 6-5 in August.

The Twins, fourth in the AL Central, have dropped 4 of 5. They lost 2 of 3 at the New York Yankees before returning home, where they’re 32-27 this season.

Tigers at Twins projected starters

RHP Casey Mize vs. RHP Zebby Matthews

Mize (11-4, 3.50 ERA) makes his 21st start. He has a 1.27 WHIP, 2.4 BB/9 and 7.9 K/9 through 105 1/3 innings.

Last start: Win, 5 IP, 2 ER, 3 H, 2 BB, 5 K in 9-5 home victory vs. Los Angeles Angels Sunday2025 road stats: 4-3, 3.52 ERA (53 2/3 IP, 21 ER), 1.42 WHIP, 8.2 K/9 in 10 startsCareer vs. Twins: 3-4, 4.86 ERA (50 IP, 27 ER), 1.22 WHIP, 7.0 K/9 in 10 starts

Matthews (3-4, 5.11 ERA) makes his 10th start. He has a 1.36 WHIP, 2.3 BB/9 and 11.7 K/9 through 44 innings.

Last start: Loss, 5 2/3 IP, 3 ER, 6 H, 1 BB, 9 K in 6-2 defeat at Yankees Monday2025 home stats: 1-1, 4.40 ERA (14 1/3 IP, 7 ER), 1.12 WHIP, 15 H, 1 BB, 20 K in 3 startsCareer vs. Tigers: 1 road start (Aug. 5), win, 5 IP, 1 ER, 5 H, 1 BB, 6 K in 6-3 defeat

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Tigers at Twins odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:23 a.m. ET.

Moneyline (ML): Tigers -115 (bet $115 to win $100) | Twins -105 (bet $105 to win $100)Run line (RL)/Against the spread (ATS): Tigers -1.5 (+145) | Twins +1.5 (-175)Over/Under (O/U): 8.5 (O: -105 | U: -115)Tigers at Twins picks and predictionsPrediction

Tigers 5, Twins 2

BET TIGERS (-115).

The Tigers have been on a roll offensively, scoring at least 4 runs in 7 of their last 9 games. They have won the last 3 starts for Mize as well. Detroit ranks as the second-best road team in the majors at 33-28.

The Twins have struggled mightily to score over the past week. They have tallied just 15 runs over their last 7 games. Minnesota is just 1-3 in its last 4 home games.

Back TIGERS (-115).

PASS.

While the Tigers -1.5 (+145) may have a case as run-line favorites, they are better played on the moneyline. Similarly, the Twins +1.5 (-175) are far too expensive to take on the run line.

BET UNDER 8.5 (-115).

Both teams are trending toward the Under. The Twins are 1-6 O/U in their last 7 games and 52-62-8 O/U on the season. They have scored just 3 runs in this series.

Meanwhile, the Tigers are 1-4 O/U in their last 5 games and have blanked their opponents in 2 of their last 3 contests. Considering those trends, back UNDER 8.5 (-115).

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