The San Diego Padres (26-15) will host the Los Angeles Angels (17-24), in the final game of a three-game series, Wednesday at 9:40 p.m. ET.
The Padres are a home favorite (-188) against the Angels (+156). The matchup on the mound for this contest is set with the San Diego Padres looking to Randy Vasquez (2-3), and Kyle Hendricks (1-4) answering the bell for the Los Angeles Angels.
The Padres took down the Angels 6-4 yesterday, with Jason Adam getting the win (1.0 IP, 0 R, 0 H, 0 K) and Fernando Tatis Jr. leading the way offensively (going 1 for 3 with a home run and two RBIs). Kenley Jansen (0.0 IP, 2 R, 1 H, 0 K) took the loss for the Angels.
Before the Padres vs. Angels matchup, here is everything you need to prepare for Wednesday’s baseball action, including viewing options.
San Diego Padres vs. Los Angeles Angels odds, line and spread
MLB odds courtesy of BetMGM Sportsbook. Odds updated Wednesday at 6:16 a.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Favorite: Padres (-188, bet $188 to win $100)Underdog: Angels (+156, bet $100 to win $156)Over/under: 8.5Padres vs. Angels: Game time and live stream infoGame day: Wednesday, May 14, 2025Game time: 9:40 p.m. ETLocation: San Diego, CaliforniaStadium: PETCO ParkTV channel: SDPA and FDSWLive stream: Watch LIVE with Fubo! (Regional restrictions may apply)
Watch Padres vs. Angels on Fubo!
Padres stats and trendsPadres betting recordsThe Padres have entered the game as favorites 22 times this season and won 16, or 72.7%, of those games.San Diego has a record of 5-2 in games when sportsbooks favor them by at least -188 on the moneyline.The moneyline for this contest implies a 65.3% chance of a victory for the Padres.San Diego and its opponents have gone over the total this season in 19 of 41 opportunities.The Padres are 25-16-0 against the spread this season.Randy Vasquez (Padres probable starter)Vasquez gets the start for the Padres, his ninth of the season. He is 2-3 with a 3.76 ERA and 18 strikeouts in 38 1/3 innings pitched.The right-hander last appeared on Saturday against the Colorado Rockies, when he tossed six innings, allowing two earned runs while giving up six hits.In eight games this season, the 26-year-old has a 3.76 ERA and 4.2 strikeouts per nine innings, while giving up a batting average of .248 to opposing batters.Vasquez is looking to pick up his third quality start of the season.Vasquez will aim to last five or more innings for his third straight appearance. He’s averaging 4.8 innings per outing.In one of his appearances this season he did not give up an earned run.The opposing Angels offense has the 13th-ranked slugging percentage (.388) and ranks fifth in MLB play with 57 home runs. It has a collective .215 batting average, and is 29th in MLB with 290 total hits and 24th in MLB play scoring 157 runs.Padres batting statsThe Padres’ 38 home runs rank 20th in Major League Baseball.Fueled by 105 extra-base hits, San Diego ranks 11th in MLB with a .401 slugging percentage this season.The Padres lead baseball with a .265 batting average.San Diego has scored 191 runs (4.7 per game) this season, which ranks 13th in MLB.The Padres have an OBP of .333 this season, which ranks sixth in MLB.San Diego has the fewest strikeouts in MLB, whiffing only 6.8 times per game on average.Angels stats and trendsAngels betting recordsThe Angels have been chosen as underdogs in 33 games this year and have walked away with the win 13 times (39.4%) in those games.Los Angeles has a win-loss record of 2-4 when favored by +156 or worse by sportsbooks this year.The Angels have an implied victory probability of 39.1% according to the moneyline set for this matchup.Los Angeles and its opponents have hit the over in 23 of its 41 games with a total set by oddsmakers this season.The Angels are 16-25-0 against the spread in their 41 games that had a posted line this season.Kyle Hendricks (Angels probable starter)The Angels are sending Hendricks (1-4) out to make his eighth start of the season. He is 1-4 with a 5.30 ERA and 21 strikeouts through 35 2/3 innings pitched.His most recent time out was on Saturday against the Baltimore Orioles, when the right-hander went five innings, surrendering three earned runs while allowing six hits.The 35-year-old has put up an ERA of 5.30, with 5.3 strikeouts per nine innings in seven games this season. Opponents are batting .231 against him.Hendricks has two quality starts under his belt this year.Hendricks will try to last five or more innings for his third straight appearance. He’s averaging 5.0 frames per outing.He has had one appearances this season in which he did not surrender an earned run.The opposing Padres offense has a collective .265 batting average, and is ninth in the league with 361 total hits and 13th in MLB action with 191 runs scored. They have the 11th-ranked slugging percentage (.401) and are 20th in all of MLB with 38 home runs.Angels batting statsThe Angels average 1.4 home runs per game to rank fifth in MLB action with 57 total home runs.This season, Los Angeles’ .388 slugging percentage ranks 13th in baseball.The Angels are 29th in the majors with a .215 batting average.Averaging 3.8 runs per game (157 total), Los Angeles is the 24th-highest scoring team in baseball.The Angels’ .276 on-base percentage is the worst in baseball.