On Tuesday, a series opener is on the schedule, with the Chicago Cubs (76-55) visiting the San Francisco Giants (63-68) at 9:45 p.m. ET.

The Giants are an underdog (+112 moneyline odds) when they square off against the Cubs (-132). The scheduled starters are Matthew Boyd (12-6) for the Chicago Cubs, and Justin Verlander (1-10) for the San Francisco Giants.

The Cubs were vicotrious 4-3 over the Angels Sunday in their last game. Nico Hoerner finished 2 for 4 with a double and an RBI to lead them offensively while Jameson Taillon was picked up the victory after throwing five innings, giving up one earned run on three hits while striking out three.

The Giants picked up a 4-3 victory over the Brewers Sunday. Luis Matos (2 for 4 with a home run and two RBIs) led the way offensively, while Jose Butto got the win on the mound after going one inning without giving up a hit or an earned run while striking out one.

Here is what you need to prepare for Tuesday’s Cubs vs. Giants contest, including viewing options.

Chicago Cubs vs. San Francisco Giants odds, line and spread

MLB odds courtesy of BetMGM Sportsbook. Odds updated Monday at 3:17 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.

Favorite: Cubs (-132, bet $132 to win $100)Underdog: Giants (+112, bet $100 to win $112)Over/under: 7.5Cubs vs. Giants: Game time and live stream infoGame day: Tuesday, August 26, 2025Game time: 9:45 p.m. ETLocation: San Francisco, CaliforniaStadium: Oracle ParkTV channel: NBCS-BA and MARQLive stream: Watch LIVE with Fubo! (Regional restrictions may apply)

Watch Cubs vs. Giants on Fubo!

Cubs stats and trendsCubs betting recordsThe Cubs have won 60, or 64.5%, of the 93 games they’ve played as favorites this season.This season Chicago has won 48 of its 71 games, or 67.6%, when favored by at least -132 on the moneyline.The implied probability of a win from the Cubs, based on the moneyline, is 56.9%.Chicago’s games have gone over the total in 61 of its 131 chances.The Cubs have an ATS record of 62-69-0 in 131 games with a spread this season.Matthew Boyd (Cubs probable starter)Boyd gets the start for the Cubs, his 26th of the season. He is 12-6 with a 2.61 ERA and 129 strikeouts in 148 2/3 innings pitched.In his last outing on Tuesday against the Milwaukee Brewers, the lefty went 5 1/3 innings, allowing four earned runs while surrendering six hits.The 34-year-old has put up a 2.61 ERA and 7.8 strikeouts per nine innings in 25 games this season, while giving up a batting average of .227 to his opponents.Boyd is looking to secure his 17th quality start of the year.Boyd is looking for his 16th straight outing lasting five or more innings. He averages 5.9 frames per appearance on the hill.He has had eight appearances this season in which he did not allow an earned run.He will face off against a Giants offense that ranks 27th in MLB with 1003 total hits (on a .231 batting average). The squad also slugs a collective .376 (27th in MLB) with 128 total home runs (23rd in MLB).In six innings over one appearance against the Giants this season, Boyd has a 3 ERA and a 0.833 WHIP while his opponents are hitting .227.Among qualifying pitchers in MLB action this season, the 34-year-old ranks sixth in ERA (2.61), ninth in WHIP (1.041), and 37th in K/9 (7.8).Cubs batting statsThe Cubs’ 178 home runs rank seventh in Major League Baseball.Hitters for Chicago rank fifth in the majors with a combined .428 team slugging percentage.The Cubs rank 14th in MLB with a .249 team batting average.Chicago has scored 648 runs this season, which ranks fifth in MLB.The Cubs have an OBP of .319 this season, which ranks 11th in MLB.Chicago has shown patience at the plate this season with the fourth-best rate of strikeouts per game (7.7) among MLB offenses.Giants stats and trendsGiants betting recordsThe Giants have come away with 25 wins in the 54 contests they have been listed as the underdogs in this season.San Francisco has a win-loss record of 15-18 when favored by +112 or worse by bookmakers this year.The moneyline set for this matchup implies the Giants have a 47.2% chance of walking away with the win.San Francisco and its opponents have hit the over in 59 of its 131 games with a total set by oddsmakers this season.The Giants have posted a record of 56-75-0 against the spread this season.Justin Verlander (Giants probable starter)The Giants will send Verlander (1-10) out for his 23rd start of the season. He is 1-10 with a 4.72 ERA and 99 strikeouts through 110 2/3 innings pitched.His most recent appearance came on Thursday against the San Diego Padres, when the right-hander tossed 4 1/3 innings, surrendering seven earned runs while giving up seven hits.The 42-year-old has a 4.72 ERA and 8.1 strikeouts per nine innings across 22 games this season, while allowing a batting average of .280 to opposing hitters.Verlander enters the matchup with seven quality starts under his belt this year.Verlander has 16 starts this season where he pitched five or more innings.He has made three appearances this season in which he did not allow an earned run.He meets a Cubs offense that ranks fifth in the league with 648 total runs scored while batting .249 as a unit. His opponent has a collective .428 slugging percentage (fifth in MLB action) and has hit a total of 178 home runs (seventh in the league).Head-to-head against the Cubs this season, Verlander has pitched five innings, giving up three earned runs on five hits while striking out three.Giants batting statsThe Giants rank 23rd in MLB play with 128 total home runs.This season, San Francisco is slugging .376, the fourth-lowest percentage in the majors.The Giants have the third-worst batting average in the league (.231).San Francisco scores the 25th-most runs in baseball (530 total, 4.0 per game).The Giants rank 21st in baseball with an on-base percentage of .308.

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