Bryan Armetta makes his DraftKings MLB Pick6 selections before Tuesday’s loaded 15-game MLB slate gets started.

As fall creeps ever-closer, pennant races in the American and National League are only heating up. Tonight, all 30 clubs across Major League Baseball are slated to take the field. That means fantasy managers will have their pick of players to choose from regardless of format. With so many superstars in action, which players should you trust (or fade)?

There’s plenty of ways to get in on Tuesday’s games with DraftKings MLB Pick6 fantasy baseball selections before tonight’s contests!

Nathaniel Lowe more than 1.5 hits + runs + RBIs

Who says you can’t grab an impact bat in August? For a Red Sox team that has struggled at first base all season, Nathaniel Lowe has been a lifesaver. The slugger was cut last week by the Nationals, allowing Boston to scoop him up off the waiver wire. Through 125 games, he’s slashing .224/.300/.386 with 17 homers and 75 RBIs. However, since moving to Beantown, the Silver Slugger is hitting an impressive .438 with a dinger and seven RBIs.

At such a late point in the season, it’s almost impossible to find quality contributors. Therefore, it’s no wonder the Sox have been playing solid ball since acquiring their newest bat. On Tuesday, Orioles hurler Kyle Bradish will make his first start in over a year following Tommy John surgery. Although the right-hander is talented, some rust is to be expected after such a long layoff. Hitting from the opposite side of the plate, Lowe is poised for another productive outing tonight.

Sandy Alcantara more than 4.5 strikeouts thrown

What a roller coaster campaign this has been for Sandy Alcantara. After missing all of last season, the former Cy Young winner entered 2025 with plenty of hype. It’s safe to say he’s fallen well short of expectations so far. Through 134.0 innings of work, the right-hander has notched a lackluster 6.04 ERA, 1.38 WHIP and 106 strikeouts. The Dominican hurler has surrendered five runs or more in ten of his 25 appearances.

As bad as Alcantara has been, there are signs he’s beginning to turn things around. Over his last two games, the 29-year-old has allowed a combined total of three hits and two runs (1.38 ERA). That includes an impressive six-inning, one-run performance against the Red Sox at Fenway Park. Tuesday’s home matchup against the sub-.500 Braves should be easier. Alcantara has delivered five or more strikeouts in three of his last four games. Another handful of K’s is a reasonable expectation tonight.

MacKenzie Gore more than 2.5 earned runs allowed

If there’s a bright spot on the mound for the Nationals, it might be MacKenzie Gore. On an otherwise terrible Washington pitching staff, the young ace has been a standout. Over 142.1 innings pitched, he owns a 4.11 ERA, 1.35 WHIP and 170 strikeouts. Granted, those aren’t eye-popping statistics. In seven starts since the All-Star break, the All-Star has accounted for a ghastly 7.88 ERA.

In all fairness, Gore has been much better during his last three outings (2.76 ERA). However, none of the lineups he faced in that stretch compare to the Yankees, tonight’s opponent. New York, fresh off of a ten-run game on Monday, clobber the ball against southpaws. The Pinstripes have a league-leading .792 OPS against left-handed pitching this season. With that in mind, it’s difficult to envision Gore keeping this Bombers offense in check.

Juan Soto more than 0.5 hits

Over the weekend, the Mets finally put up some crooked numbers at the plate. That includes last night’s 13-3 drubbing of the Phillies. Among New York’s several standout hitters, none are more prolific than Juan Soto. It’s been a mixed bag for the slugger during his first season in Queens. Regardless, he’s still slashing an impressive .251/.390/.495 with 32 homers and 77 RBIs.

For most lefties, Jesus Luzardo isn’t an ideal matchup. The seventh-year pro has been solid for the Phillies, posting a 4.10 ERA and 1.30 WHIP. In addition, he’s recorded a sparkling 2.32 ERA over his last five appearances. Still, this is Juan Soto we’re talking about; the All-Star tends to get the better of most pitchers. In his career vs. Luzardo, the Dominican has gone five-for-15 (.333 batting average) with a homer and four RBIs. A single base hit is a reasonable expectation tonight for New York’s franchise cornerstone.

Yusei Kikuchi more than 5.5 strikeouts thrown

Much like Gore and the Nationals, Yusei Kikuchi has been a stabilizing force for the Angels. Los Angeles’ starting rotation remains one of the American League’s worst. Regardless, the Halos have gotten great production from their top free agent pickup. Through 27 starts, the Japanese hurler has notched a 3.42 ERA, 1.42 WHIP and 153 strikeouts. Despite putting too many runners on, the two-time All-Star has been everything LA could have hoped for.

Whether or not he has command of his pitchers, Kikuchi is usually good for a handful of whiffs. In comparison, his opponents tonight aren’t too intimidating. The Rangers have struggled all season on offense, averaging baseball’s seventh-fewest runs per game (4.11). In addition, Texas has the eighth-most total strikeouts against left-handed pitching (328). Kikuchi is more than capable of racking up some K’s on Tuesday.

Carlos Correa more than 1.5 total bases

In what was an active trade deadline, few moves have been more impactful than Carlos Correa returning to Houston. Since rejoining the Astros, the third baseman is slashing .349/.407/.494 with three homers and 12 RBIs. Over his previous ten games, the former All-Star is batting .333 with a homer and five RBIs. On a somewhat limited offense, that kind of production has been desperately needed.

Regardless of how well the Astros have hit recently, tonight’s matchup is enticing. The awful Rockies enter tonight as baseball’s worst club. Starting tonight will be Tanner Gordon, one of several underperforming Colorado pitchers. The right-hander owns a 7.11 ERA and 1.67 WHIP through 44.1 innings. Correa has tallied a total of ten bases over his last four outings. There’s no reason to think he can’t pick up two more in this spot.

Pick6 is a peer-to-peer fantasy variant where you build a lineup (your “Pick Set”) of 2+ players and select whether or not you believe each will outperform their listed stat projection. Enter your Pick Set in Pick6 contests to compete against other users. Get enough picks correct and win a share of cash prizes.

Create a Pick Set

Create a Pick Set by choosing 2+ players from the same sport and Pick Group (a set of picks available from a group of set competitions). For each player, simply select if you think they’ll have more or less than their listed stat projection. In each Pick Set, you can not pick the same player twice and you must pick players from at least two different teams.

Enter an Amount

Once you finalize your Pick Set, choose your entry fee amount. Your entries will be automatically distributed into available contests, subject to your confirmation.

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When the games go live, use the My Picks tab to follow your picks in real time to track how your players are performing against their projections and how they stack up against other users.

Compete for Prizes

Make enough correct picks and win a share of the contests’ guaranteed prizes. Any prizes won will be credited to your DraftKings account after contests are finalized.

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