The San Diego Padres (75-59) will visit the Minnesota Twins (60-73), Friday at 8:10 p.m. ET, in the first game of a three-game series.
The Twins are an underdog (+102 on the moneyline) when they host the Padres (-122). The San Diego Padres will give the start to Nestor Cortes (2-2, 4.66 ERA), who is looking for win No. 3 on the season, and the Twins will turn to Zebby Matthews (3-4, 5.30 ERA).
The Padres’ matchup Wednesday versus the Mariners resulted in a 4-3 loss. Fernando Tatis Jr. went 2 for 5 with a double and an RBI in the defeat, while Yu Darvish threw four innings, giving up four earned runs on four hits while striking out three en route to taking the loss.
The Twins fell to the Blue Jays 9-8 Wednesday. Byron Buxton went 2 for 5 with two home runs and two RBIs in the defeat, while Michael Tonkin took the loss on the mound, pitching 2/3 of an inning, giving up one earned run on one hit while striking out one.
Here is what you need to prepare for Friday’s Padres vs. Twins game, including viewing options.
San Diego Padres vs. Minnesota Twins odds, line and spread
MLB odds courtesy of BetMGM Sportsbook. Odds updated Thursday at 6:16 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Favorite: Padres (-122, bet $122 to win $100)Underdog: Twins (+102, bet $100 to win $102)Over/under: 8.5Padres vs. Twins: Game time and live stream infoGame day: Friday, August 29, 2025Game time: 8:10 p.m. ETLocation: Minneapolis, MinnesotaStadium: Target FieldTV channel: MNNT and SDPALive stream: Watch LIVE with Fubo! (Regional restrictions may apply)
Watch Padres vs. Twins on Fubo!
Padres stats and trendsPadres betting recordsThe Padres have won 43, or 61.4%, of the 70 games they’ve played as favorites this season.San Diego has a record of 39-23 in games when bookmakers favor them by at least -122 on the moneyline.The oddsmakers’ moneyline implies a 55% chance of a victory for the Padres.San Diego’s games have gone over the total in 56 of its 134 chances.The Padres are 75-59-0 ATS in their 134 games with a spread this season.Nestor Cortes (Padres probable starter)Cortes (2-2 with a 4.66 ERA and 25 strikeouts in 29 2/3 innings pitched) gets the start for the Padres, his seventh of the season.The left-hander last appeared on Sunday against the Los Angeles Dodgers, when he tossed six scoreless innings while giving up one hit.The 30-year-old has a 4.66 ERA and 7.8 strikeouts per nine innings in six games this season, while allowing a batting average of .224 to opposing hitters.Cortes heads into the game with two quality starts under his belt this season.Cortes will look to last five or more innings for his third straight start. He’s averaging 4.8 frames per outing.He has held his opponents without an earned run in two of his six appearances this season.The opposing Twins offense has the 17th-ranked slugging percentage (.398) and ranks 14th in MLB play with 159 home runs. It has a collective .238 batting average, and is 25th in MLB with 1058 total hits and 24th in MLB play scoring 556 runs.Padres batting statsThe Padres have hit just 116 homers this season, which ranks 29th in the league.Fueled by 351 extra-base hits, San Diego ranks 25th in MLB with a .385 slugging percentage this season.The Padres rank eighth in MLB with a .251 team batting average.San Diego ranks 23rd in the majors with 564 total runs scored this season.The Padres have an OBP of .321 this season, which ranks ninth in MLB.San Diego has shown patience at the plate this season with the third-best rate of strikeouts per game (7.0) among MLB offenses.Twins stats and trendsTwins betting recordsThe Twins have come away with 20 wins in the 53 contests they have been listed as the underdogs in this season.Minnesota has a win-loss record of 15-24 when favored by +102 or worse by oddsmakers this year.The Twins have an implied victory probability of 49.5% according to the moneyline set by sportsbooks for this matchup.Minnesota’s games have gone over the total in 59 of its 132 opportunities.The Twins have an against the spread record of 68-64-0 in 132 games with a line this season.Zebby Matthews (Twins probable starter)Matthews gets the start for the Twins, his 12th of the season. He is 3-4 with a 5.30 ERA and 67 strikeouts in 52 2/3 innings pitched.In his last time out on Friday, the right-hander went 4 2/3 innings against the Chicago White Sox, allowing four earned runs while surrendering eight hits.In 11 games this season, the 25-year-old has amassed an ERA of 5.30, with 11.4 strikeouts per nine innings. Opponents are hitting .288 against him.Matthews heads into the matchup with one quality start under his belt this season.Matthews will try to record his sixth outing of five or more innings pitched this season. He averages 4.7 innings per appearance.In one of his 11 total appearances this season he has not given up an earned run.He will face off against a Padres offense that ranks 14th in the league with 1123 total hits (on a .251 batting average). The team also slugs a collective .385 (25th in the league) with 116 total home runs (29th in MLB action).Twins batting statsThe Twins average 1.2 home runs per game to rank 14th in baseball with 159 total home runs.This season, Minnesota’s .398 slugging percentage ranks 17th in the majors.The Twins have the 23rd-ranked batting average in the league (.238).The offense for Minnesota is the No. 24 offense in the majors, scoring 4.2 runs per game (556 total runs).The Twins rank 20th in baseball with an on-base percentage of .310.