Data Skrive
Robbie Ray starts for the San Francisco Giants on Friday against Gunnar Henderson and the Baltimore Orioles. First pitch is at 10:15 p.m. ET at Oracle Park. The Giants are the favorite in this one, at -158, while the underdog Orioles have +133 odds to play spoiler. San Francisco is the run-line favorite (-1.5). The total is 7.5 runs for the game.
Take a look at everything you need to know from a betting perspective on the Giants-Orioles game, regarding the run line, moneyline and total, plus expert picks.
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Cubs vs. Giants Highlights | MLB on FOX 
Check out the best moments between Chicago Cubs and the San Francisco Giants.
Giants vs. Orioles Game Information & OddsWhen: Friday, August 29, 2025 at 10:15 p.m. ETWhere: Oracle Park in San Francisco, CaliforniaHow to watch on TV: Apple TV+ Favorite Favorite Moneyline Underdog Moneyline Total Over Total Odds Under Total Odds Run Line Favorite Run Line Odds Underdog Run Line Odds Giants -158 +133 7.5 -108 -112 -1.5 +145 -174 Giants vs. Orioles PredictionScore Prediction: Giants 4, Orioles 3Total Prediction: Under 7.5 runsWin Probabilities: Giants 55%, Orioles 45%Giants vs. Orioles Betting InsightsThe Giants have entered the game as favorites 77 times this season and won 39, or 50.6%, of those games.San Francisco has entered 31 games this season favored by -158 or more and is 15-16 in those contests.Sportsbooks have implied with the moneyline set for this matchup that the Giants have a 61.2% chance to win.The Orioles have won in 32, or 44.4%, of the 72 contests they have been named as odds-on underdogs this year.This season, Baltimore has come away with a win five times in 17 chances when named as an underdog of at least +133 or longer on the moneyline.Sportsbooks have implied with the moneyline set for this matchup that the Orioles have a 42.9% chance of pulling out a win.Giants Recent Betting PerformanceIn the last 10 games, the Giants were listed as the moneyline favorite by bookmakers only once, a game they won.In their last 10 matchups, the Giants and their opponents combined to hit the over four times (all 10 of the games had set totals).The Giants have a 7-3-0 record against the spread over their past 10 games.Giants Recent Stats Stat Avg/Total Record 6-4 Runs Per Game 4.6 HR 20 ERA 3.65 K/9 7.7 Giants Player InsightsRafael Devers leads the Giants with 27 home runs and 89 runs batted in.In all of Major League Baseball, Devers ranks 16th in homers and 11th in RBI.Devers has collected a hit in three games in a row. During his last five outings he is hitting .438 with a double, two home runs, three walks and six RBIs.Jung Hoo Lee is batting .261 with 30 doubles, 10 triples, seven home runs and 41 walks.Lee ranks 238th in homers and 142nd in RBI among all hitters in the majors.Lee has four games in a row with at least one hit. In his last five games he is hitting .238 with a double, a walk and an RBI.Willy Adames has 18 doubles, two triples, 24 home runs and 64 walks while hitting .224.Heliot Ramos‘ .265 batting average leads his team.Orioles Recent Betting PerformanceThe Orioles have played as underdogs in seven of their past 10 games and won two of those contests.In their last 10 games with a total, the Orioles and their opponents have failed to hit the over six times.The Orioles have a record of 5-5-0 ATS over their last 10 games.Orioles Recent Stats Stat Avg/Total Record 3-7 Runs Per Game 3.7 HR 10 ERA 4.40 K/9 7.9 Orioles Player InsightsHenderson paces the Orioles in home runs (16), runs batted in (59) and has a team-high batting average of .277.Henderson’s home run total puts him 92nd in MLB, and he ranks 85th in RBI.Jackson Holliday has 18 doubles, two triples, 15 home runs and 38 walks while batting .242.Holliday is 109th in homers and 134th in RBI among all hitters in the majors.Colton Cowser is batting .219 with 11 doubles, 12 home runs and 17 walks.Ryan Mountcastle is batting .251 with 14 doubles, four home runs and 11 walks.Cubs vs. Giants Highlights | MLB on FOX
Check out the best moments between Chicago Cubs and the San Francisco Giants.
FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.
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