The New York Mets (76-69) and the Philadelphia Phillies (85-60) play the third game of a 4-game series Wednesday. First pitch from Citizens Bank Park is at 6:45 p.m. ET. Let’s analyze BetMGM Sportsbook’s MLB odds around the Mets vs. Phillies odds and make our expert MLB picks and predictions for the best bets.

Season series: Mets lead 7-4

After winning Monday’s series opener 1-0, the Phillies beat the Mets 9-3 Tuesday, cashing as -126 home favorites with the Over (8) hitting. DH Kyle Schwarber hit his 50th home run, and SP Ranger Suárez (win, 6 IP, 0 ER, 1 H, 3 BB, 12 K) improved to 12-6 on the season. Philadelphia is in first place in the NL East, 9 games ahead of the second-place Mets.

3B Mark Vientos hit a solo shot in the seventh inning for the Mets, who have lost 4 straight games. New York is in the final NL Wild Card spot, 2 games ahead of the San Francisco Giants.

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Mets at Phillies projected starters

RHP Clay Holmes vs. LHP Cristopher Sánchez

Holmes (11-7, 3.61 ERA) makes his 29th start. He has a 1.33 WHIP, 3.6 BB/9 and 7.2 K/9 through 147 innings.

Last start: Loss, 4 2/3 IP, 2 ER (3 R), 5 H, 3 BB, 6 K in 6-2 defeat at Detroit Tigers Sept. 3Career vs. Phillies: 0-0, 6.75 ERA (5 1/3 IP, 4 ER), 1.88 WHIP, 9 H, 1 BB, 6 K in 5 relief appearances; last faced them in 2024

Sánchez (12-5, 2.60 ERA) makes his 29th start. He has a 1.11 WHIP, 2.1 BB/9 and 9.5 K/9 through 176 1/3 innings.

Last start: Win, 7 IP, 1 ER, 6 H, 1 BB, 5 K in 9-3 victory at Miami Marlins Friday2025 vs. Mets: 0-2, 9.82 ERA (7 1/3 IP, 8 ER), 2.32 WHIP, 12 H, 5 BB, 6 K in 2 startsCareer vs. Mets: 2-4, 4.63 ERA (44 2/3 IP, 23 ER) 1.32 WHIP, 2.6 BB/9, 9.2 K/9 in 11 games (8 starts)Mets at Phillies odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:16 a.m. ET.

Moneyline (ML): Mets +145 (bet $100 to win $100) | Phillies -175 (bet $175 to win $100)Run line (RL)/Against the spread (ATS): Mets +1.5 (-150) | Phillies -1.5 (+125)Over/Under (O/U): 8 (O: -102 | U: -118)

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Mets at Phillies picks and predictionsPrediction

Phillies 4, Mets 3

Philadelphia (-175) took the first 2 games of this set and will likely win again Wednesday, but the straddle is too high in this market to bet either side.

PASS on the moneyline.

The Mets have covered the +1.5 run line in 4 of Holmes’ last 6 starts and in 4 of their previous 6 games entering this series.

BET METS +1.5 (-150).

The Under is 6-3-2 in Philadelphia’s last 11 games and 4-1-1 in New York’s last 6 contests.

BET UNDER 8 (-118).

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