The Chicago White Sox and Miguel Vargas hit the field in the first game of a three-game series against Kyle Tucker and the Chicago Cubs, on Friday at Wrigley Field.
The Cubs’ .250 batting average ranks 13th in MLB. The White Sox have the 20th-ranked ERA (4.05) in the majors this season.
Here is everything you need to get ready for Friday’s Cubs vs. White Sox matchup, including viewing options.
Cubs vs. White Sox: live stream info, TV channel & game timeGame day: Friday, May 16, 2025Game time: 2:20 p.m. ETLocation: Chicago, IllinoisStadium: Wrigley FieldTV channel: Chicago Sports NetworkLive stream: Watch LIVE with Fubo! (Regional restrictions may apply)
Cubs vs. White Sox odds & betting linesFavorite: Cubs (-227, bet $227 to win $100)Underdog: White Sox (+188, bet $100 to win $188)Over/under: 12.5
MLB odds courtesy of BetMGM Sportsbook. Odds updated Thursday at 9:09 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.