At Target Field on Friday, the Minnesota Twins (64-82) open a three-game series versus the Arizona Diamondbacks (73-74), at 8:10 p.m. ET.
The Diamondbacks (+110 underdog moneyline odds) visit the Twins (-131). The scheduled starters are Pablo Lopez (5-4) for the Minnesota Twins, and Brandon Pfaadt (13-8) for the Arizona Diamondbacks.
The Twins lost 4-3 to the Angels Wednesday, with Cole Sands (1 2/3 innings, giving up one earned run on one hit) on the line for the loss. James Outman went 2 for 3 with a double, a home run and an RBI to lead the Twins offensively in the defeat.
The Diamondbacks earned a 5-3 victory against the Giants Wednesday. Geraldo Perdomo (2 for 4 with a home run and two RBIs) led the way offensively, while Eduardo Rodriguez got the win on the mound after going 6 1/3 innings without giving up an earned run on two hits, while striking out six.
Before this Twins vs. Diamondbacks showdown, here is what you need to prepare for Friday’s MLB action, including viewing options.
Minnesota Twins vs. Arizona Diamondbacks odds, line and spread
MLB odds courtesy of BetMGM Sportsbook. Odds updated Friday at 12:16 a.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Favorite: Twins (-131, bet $131 to win $100)Underdog: Diamondbacks (+110, bet $100 to win $110)Over/under: 8.5Twins vs. Diamondbacks: Game time and live stream infoGame day: Friday, September 12, 2025Game time: 8:10 p.m. ETLocation: Minneapolis, MinnesotaStadium: Target FieldTV channel: MNNT and ARIDLive stream: Watch LIVE with Fubo! (Regional restrictions may apply)
Watch Twins vs. Diamondbacks on Fubo!
Twins stats and trendsTwins betting recordsThe Twins have entered the game as favorites 83 times this season and won 38, or 45.8%, of those games.Minnesota has a record of 23-21 in games when bookmakers favor them by at least -131 on the moneyline.The implied probability of a win from the Twins, based on the moneyline, is 56.7%.Minnesota and its opponents have gone over the total this season in 68 of 145 opportunities.The Twins are 74-71-0 against the spread in their 145 chances this season.Pablo Lopez (Twins probable starter)Lopez makes the start for the Twins, his 13th of the season. He is 5-4 with a 2.83 ERA and 65 strikeouts through 66 2/3 innings pitched.In his last appearance on Friday, the righty went six innings against the Kansas City Royals, giving up two earned runs while surrendering six hits.The 29-year-old has amassed an ERA of 2.83, with 8.8 strikeouts per nine innings, in 12 games this season. Opponents are batting .227 against him.Lopez is looking to record his fifth quality start of the season.Lopez is looking for his 10th straight outing lasting five or more innings. He averages 5.5 frames per appearance on the hill.In two of his appearances this season he did not give up an earned run.He will face off against a Diamondbacks offense that ranks ninth in MLB with 1242 total hits (on a .250 batting average). The team also slugs a collective .434 (third in MLB) with 199 total home runs (sixth in MLB).Twins batting statsThe Twins rank 12th in Major League Baseball with 173 home runs.Hitters for Minnesota have combined for a team rank of 17th in the majors with a .398 team slugging percentage.The Twins rank 23rd in MLB with a .239 team batting average.Minnesota has scored the 24th-most runs in the majors this season with 617 (4.2 per game).The Twins have the 21st-ranked on-base percentage in MLB this season (.312).Minnesota ranks 15th in strikeouts per game (8.3) among MLB offenses.Diamondbacks stats and trendsDiamondbacks betting recordsThe Diamondbacks have been victorious in 30, or 48.4%, of the 62 contests they have been chosen as underdogs in this season.Arizona has a win-loss record of 20-16 when favored by +110 or worse by oddsmakers this year.The moneyline set for this matchup implies the Diamondbacks have a 47.6% chance of walking away with the win.Arizona and its opponents have hit the over in 70 of its 146 games with a total set by oddsmakers this season.The Diamondbacks are 74-72-0 against the spread in their 146 games that had a posted line this season.Brandon Pfaadt (Diamondbacks probable starter)Pfaadt gets the start for the Diamondbacks, his 30th of the season. He is 13-8 with a 5.18 ERA and 129 strikeouts in 153 2/3 innings pitched.In his last appearance on Sunday against the Boston Red Sox, the right-hander tossed six innings, giving up one earned run while surrendering six hits.The 26-year-old has a 5.18 ERA and 7.6 strikeouts per nine innings during 29 games this season, while giving up a batting average of .286 to his opponents.Pfaadt enters the outing with 10 quality starts under his belt this season.Pfaadt is looking to secure his 23rd start of five or more innings this season in this game.He has had three appearances this season in which he did not give up an earned run.He will take the hill against a Twins team that is hitting .239 as a unit (23rd in the MLB). They are also slugging a collective .398 (17th in the league) with 173 total home runs (12th in MLB play).The 26-year-old ranks 49th in ERA (5.18), 49th in WHIP (1.379), and 39th in K/9 (7.6) among qualifying pitchers in MLB play this season.Diamondbacks batting statsThe Diamondbacks are sixth in baseball with 199 home runs. They average 1.4 per game.This season, Arizona ranks third in baseball with a .434 slugging percentage.The Diamondbacks have the 11th-ranked batting average in the majors (.250).Arizona is the sixth-highest scoring team in the majors, averaging 4.9 runs per game (724 total).The Diamondbacks’ .323 on-base percentage ranks eighth-best in the majors.