The Chicago White Sox (57-92) take on the Cleveland Guardians (77-71), who will be trying to extend a three-game winning streak, Sunday at 1:40 p.m. ET, at Progressive Field.
The White Sox are an underdog (+142 on the moneyline) when they take on the Guardians (-171). The starting pitchers are Slade Cecconi (6-6) for the Cleveland Guardians, and Yoendrys Gomez (3-2) for the Chicago White Sox.
These clubs meet again after the Guardians defeated the White Sox 3-1 yesterday. Parker Messick registered the win for the Guardians (6.0 IP, 1 R, 7 H, 4 K), and CJ Kayfus led the way offensively (1 for 2 with a home run and two RBIs). Davis Martin (5.0 IP, 2 R, 5 H, 3 K) took the loss for the White Sox.
Prepare for the Guardians vs. White Sox with everything you need to know about Sunday’s game, including viewing options.
Cleveland Guardians vs. Chicago White Sox odds, line and spread
MLB odds courtesy of BetMGM Sportsbook. Odds updated Sunday at 3:16 a.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Favorite: Guardians (-171, bet $171 to win $100)Underdog: White Sox (+142, bet $100 to win $142)Over/under: 8.5Guardians vs. White Sox: Game time and live stream infoGame day: Sunday, September 14, 2025Game time: 1:40 p.m. ETLocation: Cleveland, OhioStadium: Progressive FieldTV channel: CLEG and CHSNLive stream: Watch LIVE with Fubo! (Regional restrictions may apply)
Watch Guardians vs. White Sox on Fubo!
Guardians stats and trendsGuardians betting recordsThe Guardians have entered the game as favorites 63 times this season and won 39, or 61.9%, of those games.This season Cleveland has won seven of its eight games when favored by at least -171 on the moneyline.The implied probability of a win from the Guardians, based on the moneyline, is 63.1%.Games involving Cleveland have gone over the total set by bookmakers in 62 of 146 chances this season.The Guardians are 76-70-0 against the spread this season.Slade Cecconi (Guardians probable starter)Cecconi gets the start for the Guardians, his 21st of the season. He is 6-6 with a 4.45 ERA and 94 strikeouts in 115 1/3 innings pitched.In his most recent time out on Monday, the right-hander went eight scoreless innings against the Kansas City Royals while surrendering one hit.The 26-year-old has an ERA of 4.45, with 7.3 strikeouts per nine innings, in 20 games this season. Opponents are hitting .257 against him.Cecconi has 10 quality starts this year.Cecconi will try to prolong a five-game streak of pitching five or more innings (he’s averaging 5.8 innings per appearance).He has held his opponents without an earned run in two of his 20 outings this season.He will face off against a White Sox squad that is hitting .235 as a unit (27th in MLB). It is also slugging a collective .376 (28th in MLB) with 150 total home runs (22nd in MLB).Cecconi has a 15.00 ERA and a 3.000 WHIP against the White Sox this season in three innings pitched, allowing a .471 batting average over one appearance.Guardians batting statsThe Guardians’ 153 home runs rank 21st in Major League Baseball.Hitters for Cleveland have combined to rank 29th in the majors with a .370 team slugging percentage.The Guardians have a team batting average of just .225 this season, which ranks last among MLB teams.Cleveland is among the lowest-scoring teams in the majors, ranking 27th with just 577 total runs (3.9 per game) this season.The Guardians are among the worst in the league at getting on base, ranking 29th with an OBP of .296.Cleveland ranks 14th with an average of 8.2 strikeouts per game.White Sox stats and trendsWhite Sox betting recordsThe White Sox have come away with 56 wins in the 147 contests they have been listed as the underdogs in this season.This season, Chicago has been victorious 25 times in 80 chances when named as an underdog of at least +142 or longer on the moneyline.The moneyline set for this matchup implies the White Sox have a 41.3% chance of walking away with the win.Chicago and its opponents have gone over in 68 of its 149 games with a total set by sportsbooks this season.The White Sox are 87-62-0 against the spread in their 149 games that had a posted line this season.Yoendrys Gomez (White Sox probable starter)Gomez (3-2) gets the starting nod for the White Sox in his seventh start of the season. He’s put together a 5.05 ERA in 46 1/3 innings pitched, with 45 strikeouts.In his most recent appearance on Tuesday, the right-hander tossed five innings against the Tampa Bay Rays, allowing four earned runs while surrendering five hits.In 18 games this season, the 25-year-old has amassed a 5.05 ERA and 8.7 strikeouts per nine innings, while giving up a batting average of .244 to his opponents.Gomez has yet to record a quality start this season.Gomez will try to prolong a three-game streak of going five or more innings (he’s averaging 2.6 frames per appearance).He has had seven appearances this season that he kept his opponents to zero earned runs.The opposing Guardians offense has the 29th-ranked slugging percentage (.370) and ranks 21st in home runs hit (153) in all of MLB. They have a collective .225 batting average, and are last in the league with 1089 total hits and 27th in MLB play scoring 577 runs.Head-to-head against the Guardians this season, Gomez has thrown three innings, giving up one earned run on three hits.White Sox batting statsThe White Sox rank 22nd in MLB play with 150 home runs. They average 1.0 per game.This season, Chicago has the third-lowest slugging percentage in the majors (.376).The White Sox have the fourth-worst batting average in the league (.235).Chicago is the fifth-lowest scoring team in MLB play averaging 4.0 runs per game (598 total).The White Sox are 27th in MLB with a .304 on-base percentage.