Byron Buxton, coming off a one-hit showing in his last game (1-for-5), will take the field for the Minnesota Twins versus Parker Messick and the Cleveland Guardians on Friday. First pitch is at 8:10 p.m. ET on MNNT and CLEG.

Find odds, stats, and more below to make your Byron Buxton player prop bets.

Buxton has accumulated a team-high batting average of .270, while leading the Twins in home runs (31) and runs batted in (76). Among all hitters in baseball, Buxton’s home run total ranks 14th and his RBI tally ranks 53rd.

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Byron Buxton Prop Bets and OddsHits Prop: 1.5 hits (Over odds: +200)Home Runs Prop: 0.5 home runs (Over odds: +350)RBI Prop: 0.5 RBI (Over odds: +165)Runs Prop: 0.5 runs (Over odds: -110)Total Bases Prop: 1.5 total bases (Over odds: -115)Stolen Bases Prop: 0.5 stolen bases (Over odds: +500)How to Watch Minnesota Twins vs. Cleveland GuardiansMatchup: Minnesota Twins vs. Cleveland GuardiansTime: 8:10 p.m. ETDate: Friday, September 19, 2025TV Channel: MNNT and CLEGLive Stream: Fubo (Watch now! – Regional restrictions may apply)Byron Buxton prop bet insightsBuxton has reached base with a hit 74 times this year in 117 games played (63.2%), including multiple hits on 37 occasions (31.6%).In 23.9% of his games this season, he has hit a long ball (28 of 117). During the 2025 campaign, he’s taken the pitcher deep in 6.2% of his trips to the dish.Buxton has scored at least one run 64 times this season in 117 games played (54.7%), including 24 times scoring multiple runs (20.5%).He has produced at least one run 47 times this season in 117 tries (40.2%), including plating multiple runs in 17.9% of games (21 times) and producing three or more of his team’s runs on five occasions.Buxton has gone down on strikes in 70.9% of his 117 games this season, with more than one strikeout in 31.6% of them (37).

MLB odds courtesy of BetMGM Sportsbook. Odds updated Friday at 1:25 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.

Byron Buxton stats against the Guardians5/1/2025: 2-for-5, 0 HR, 0 RBI, 0 R, 1 K, 0 BB, 0 SB4/30/2025: 1-for-4, 0 HR, 0 RBI, 0 R, 2 K, 0 BB, 1 SB4/29/2025: 0-for-3, 0 HR, 0 RBI, 0 R, 1 K, 1 BB, 0 SB4/28/2025: 2-for-5, 0 HR, 2 RBI, 1 R, 1 K, 0 BB, 0 SB9/19/2024: 0-for-5, 0 HR, 0 RBI, 0 R, 3 K, 0 BB, 0 SB9/17/2024: 1-for-3, 0 HR, 0 RBI, 1 R, 0 K, 2 BB, 0 SB9/16/2024: 1-for-4, 0 HR, 2 RBI, 0 R, 1 K, 0 BB, 0 SB8/11/2024: 2-for-4, 2 HR, 3 RBI, 2 R, 1 K, 0 BB, 0 SB8/10/2024: 1-for-4, 0 HR, 0 RBI, 0 R, 0 K, 0 BB, 0 SB8/9/2024: 0-for-1, 0 HR, 0 RBI, 0 R, 0 K, 0 BB, 0 SBGuardians starter: Parker MessickMessick (3-0) takes the hill for the Guardians in his sixth start of the season. He has produced a 1.84 ERA in 29 1/3 innings pitched, with 22 Ks.The left-hander’s most recent appearance came on Saturday versus the Chicago White Sox, as he tossed six innings, giving up one earned run while allowing seven hits.The 24-year-old has registered an ERA of 1.84, with 6.8 strikeouts per nine innings, in five games this season. Opponents are hitting .302 against him.Messick is aiming for his third straight quality start.