Kyle Manzardo went hitless in his previous game (0 for 2), but will have another crack at it when the Cleveland Guardians square off versus Pablo Lopez and the Minnesota Twins on Friday at 8:10 p.m. ET on MNNT and CLEG.
Find odds, stats, and more below to make your Kyle Manzardo player prop bets.
Manzardo has 17 doubles, two triples, 26 home runs and 47 walks while batting .240. Manzardo ranks 39th in homers and 88th in RBI among all batters in baseball.
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Kyle Manzardo Prop Bets and OddsHits Prop: 0.5 hits (Over odds: -175)Home Runs Prop: 0.5 home runs (Over odds: +475)RBI Prop: 0.5 RBI (Over odds: +150)Runs Prop: 0.5 runs (Over odds: +150)Total Bases Prop: 0.5 total bases (Over odds: -182)How to Watch Cleveland Guardians vs. Minnesota TwinsMatchup: Cleveland Guardians vs. Minnesota TwinsTime: 8:10 p.m. ETDate: Friday, September 19, 2025TV Channel: MNNT and CLEGLive Stream: Fubo (Watch now! – Regional restrictions may apply)Kyle Manzardo vs. Pablo LopezManzardo is 0 for 5 in his career versus Pablo Lopez.Manzardo is 0 for 3 when matching up against Pablo Lopez this season.Last year against Pablo Lopez, Manzardo was 0 for 2 at the plate.Kyle Manzardo prop bet insightsIn 79 of 132 games this year (59.8%) Manzardo has gotten a hit, and in 21 of those contests (15.9%) he posted at least two hits.In 24 of 132 games this season, he has gone yard (18.2%). He’s taken the pitcher deep in 5.3% of his trips to the plate in 2025.Manzardo has scored in 30.3% of his 132 games this season, with two or more runs scored in 3.0% of those contests (four).He has notched at least one RBI in 37.1% of his games this season (49 of 132), with two or more RBI in 13 of those contests (9.8%). He has also driven in three or more of his team’s runs in four contests.Manzardo has struck out in 91 of 132 games this season, with multiple punchouts in 28 of them.
MLB odds courtesy of BetMGM Sportsbook. Odds updated Friday at 6:24 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Kyle Manzardo stats against the Twins8/3/2025: 0-for-3, 0 HR, 0 RBI, 0 R, 1 K, 1 BB, 0 SB8/2/2025: 0-for-4, 0 HR, 0 RBI, 0 R, 2 K, 0 BB, 0 SB8/1/2025: 2-for-4, 0 HR, 1 RBI, 0 R, 1 K, 0 BB, 0 SB5/21/2025: 0-for-5, 0 HR, 0 RBI, 0 R, 1 K, 0 BB, 0 SB5/21/2025: 1-for-3, 0 HR, 1 RBI, 0 R, 0 K, 1 BB, 0 SB5/1/2025: 1-for-3, 0 HR, 1 RBI, 0 R, 2 K, 2 BB, 0 SB4/30/2025: 0-for-3, 0 HR, 0 RBI, 0 R, 1 K, 0 BB, 0 SB4/29/2025: 2-for-3, 1 HR, 1 RBI, 1 R, 0 K, 1 BB, 0 SB4/28/2025: 1-for-4, 0 HR, 0 RBI, 0 R, 1 K, 0 BB, 0 SB9/19/2024: 3-for-3, 1 HR, 1 RBI, 1 R, 0 K, 0 BB, 0 SBTwins starter: Pablo LopezThe Twins will call on Lopez (5-4) to make his 14th start of the season. He is 5-4 with a 2.64 ERA and 71 Ks in 71 2/3 innings pitched.His most recent outing came on Saturday versus the Arizona Diamondbacks, when the righty went five innings, allowing no earned runs while surrendering four hits.The 29-year-old has put up a 2.64 ERA and 8.9 Ks per nine innings in 13 games this season, while allowing a batting average of .226 to opposing batters.Lopez enters the outing after racking up four quality starts.