The Los Angeles Angels (70-87) will host the Kansas City Royals (79-78), in the second game of a three-game series, Wednesday at 9:38 p.m. ET.
The Royals are road underdogs (+104) at the Angels (-124). The Los Angeles Angels will give the start to Yusei Kikuchi (6-11, 4.05 ERA), who is looking for win No. 7 on the season, and the Royals will turn to Stephen Kolek (5-6, 3.54 ERA).
The Royals beat the Angels 8-4 yesterday, with Cole Ragans getting the win (5.0 IP, 2 R, 3 H, 10 K) and Maikel Garcia leading the way offensively (going 3 for 3 with two doubles and an RBI). Samuel Aldegheri (4.2 IP, 3 R, 7 H, 3 K) took the loss for the Angels.
Ahead of watching this Angels vs. Royals matchup, here is what you need to know about Wednesday’s action on the diamond, including viewing options.
Los Angeles Angels vs. Kansas City Royals odds, line and spread
MLB odds courtesy of BetMGM Sportsbook. Odds updated Wednesday at 3:16 a.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Favorite: Angels (-124, bet $124 to win $100)Underdog: Royals (+104, bet $100 to win $104)Over/under: 8.5Angels vs. Royals: Game time and live stream infoGame day: Wednesday, September 24, 2025Game time: 9:38 p.m. ETLocation: Anaheim, CaliforniaStadium: Angel StadiumTV channel: FDSW and FDSKCLive stream: Watch LIVE with Fubo! (Regional restrictions may apply)
Watch Angels vs. Royals on Fubo!
Angels stats and trendsAngels betting recordsThe Angels have entered the game as favorites 39 times this season and won 19, or 48.7%, of those games.Los Angeles is 14-15 this season when entering a game favored by -124 or more on the moneyline.The implied probability of a win from the Angels, based on the moneyline, is 55.4%.Los Angeles and its opponents have hit the over in 84 of its 157 games with a total this season.The Angels have an ATS record of 82-75-0 in 157 games with a spread this season.Yusei Kikuchi (Angels probable starter)Kikuchi makes the start for the Angels, his 33rd of the season. He is 6-11 with a 4.05 ERA and 168 strikeouts through 173 1/3 innings pitched.The lefty’s last time out came on Thursday against the Milwaukee Brewers, when he went 5 2/3 innings, surrendering two earned runs while allowing five hits.The 34-year-old has an ERA of 4.05, with 8.7 strikeouts per nine innings, in 32 games this season. Opponents are hitting .266 against him.Kikuchi is looking to record his 12th quality start of the season.Kikuchi will aim to pitch five or more innings for his third straight appearance. He’s averaging 5.4 innings per outing.He has had four appearances this season in which he kept his opponents to zero earned runs.He will face a Royals offense that ranks 26th in the league with 624 runs while batting .248 as a squad. It has a collective .397 slugging percentage (16th in MLB action) and has hit a total of 153 home runs (25th in MLB).Among qualifying pitchers in MLB action this season, the 34-year-old ranks 30th in ERA (4.05), 51st in WHIP (1.454), and 24th in K/9 (8.7).Angels batting statsThe Angels have hit 219 homers this season, which ranks fourth in the league.Fueled by 443 extra-base hits, Los Angeles ranks 15th in MLB with a .398 slugging percentage this season.The Angels have a team batting average of just .226 this season, which ranks 29th among MLB teams.Los Angeles has scored 659 runs (4.2 per game) this season, which ranks 25th in MLB.The Angels have an OBP of just .299 this season, which ranks 28th in MLB.Los Angeles ranks last in MLB in strikeouts per game with an average of 10.1 whiffs per contest.Royals stats and trendsRoyals betting recordsThe Royals have been victorious in 41, or 45.1%, of the 91 contests they have been chosen as underdogs in this season.This season, Kansas City has come away with a win 28 times in 68 chances when named as an underdog of at least +104 or longer on the moneyline.Oddsmakers have implied with the moneyline set for this matchup that the Royals have a 49% chance of pulling out a win.Kansas City and its opponents have gone over in 69 of its 157 games with a total set by sportsbooks this season.The Royals are 78-79-0 against the spread in their 157 games that had a posted line this season.Stephen Kolek (Royals probable starter)The Royals are sending Kolek (5-6) out to make his 19th start of the season. He is 5-6 with a 3.54 ERA and 75 strikeouts over 106 2/3 innings pitched.In his most recent time out on Thursday against the Seattle Mariners, the righty threw 7 1/3 innings, allowing one earned run while surrendering two hits.The 28-year-old has amassed an ERA of 3.54, with 6.3 strikeouts per nine innings in 18 games this season. Opponents are batting .236 against him.Kolek is trying to continue a fifth-game quality start streak in this game.Kolek will look to build on a nine-game streak of lasting five or more innings (he’s averaging 5.9 frames per outing).He has had four appearances this season that he kept his opponents to zero earned runs.He will take the mound against an Angels offense that ranks 29th in the league with 1179 total hits (on a .226 batting average). The squad also slugs a collective .398 (15th in the league) with 219 total home runs (fourth in MLB action).Royals batting statsThe Royals average 1.0 home run per game to rank 25th in baseball with 153 total home runs.This season, Kansas City is 16th in baseball, slugging .397.The Royals have the 15th-ranked batting average in the league (.248).Kansas City scores the fifth-fewest runs in baseball (624 total, 4.0 per game).The Royals’ .309 on-base percentage is 22nd in baseball.