On Friday, a series opener is on the schedule, with the Philadelphia Phillies (94-65) hosting the Minnesota Twins (69-90) at 6:45 p.m. ET.
The Phillies are the home favorite (-169) against the Twins (+142). The Phillies will start Aaron Nola (4-10) against the Twins and Joe Ryan (13-9).
The Phillies won their most recent contest versus the Marlins by a 1-0 score yesterday, with Walker Buehler picking up the win pitching going five innings without giving up an earned run on three hits, while striking out two. Bryson Stott went 2 for 3 to lead them offensively.
The Twins took down the Rangers 4-0 yesterday, with Bailey Ober registering the win while throwing six innings without giving up an earned run on two hits, while striking out five. Byron Buxton went 2 for 4 with two home runs and four RBIs to pace the Twins’ offense.
Ahead of this Phillies vs. Twins matchup, here’s everything you need to prepare for Friday’s MLB action, including viewing options.
Philadelphia Phillies vs. Minnesota Twins odds, line and spread
MLB odds courtesy of BetMGM Sportsbook. Odds updated Friday at 3:17 a.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Favorite: Phillies (-169, bet $169 to win $100)Underdog: Twins (+142, bet $100 to win $142)Over/under: 8.5Phillies vs. Twins: Game time and live stream infoGame day: Friday, September 26, 2025Game time: 6:45 p.m. ETLocation: Philadelphia, PennsylvaniaStadium: Citizens Bank ParkTV channel: NBCS-PH and MNNTLive stream: Watch LIVE with Fubo! (Regional restrictions may apply)
Watch Phillies vs. Twins on Fubo!
Phillies stats and trendsPhillies betting recordsThe Phillies have won 78, or 61.9%, of the 126 games they’ve played as favorites this season.Philadelphia is 37-14 this season when entering a game favored by -169 or more on the moneyline.The moneyline for this contest implies a 62.8% chance of a victory for the Phillies.So far this season, Philadelphia and its opponents have hit the over in 71 of 159 games with a total.The Phillies are 80-79-0 ATS in their 159 games with a spread this season.Aaron Nola (Phillies probable starter)The Phillies are sending Nola (4-10) out for his 17th start of the season. He is 4-10 with a 6.46 ERA and 88 strikeouts through 86 1/3 innings pitched.The right-hander’s last appearance came on Sunday against the Arizona Diamondbacks, when he tossed 5 1/3 innings, surrendering four earned runs while giving up seven hits.In 16 games this season, the 32-year-old has put up an ERA of 6.46, with 9.2 strikeouts per nine innings. Opponents are batting .281 against him.Nola has five quality starts under his belt this year.Nola will try to prolong a seven-game streak of lasting five or more innings (he’s averaging 5.4 innings per outing).He has held his opponents without an earned run in two of his 16 appearances this season.He meets a Twins offense that ranks 21st in the league with 671 runs while batting .239 as a unit. It has a collective .397 slugging percentage (16th in MLB play) and has hit a total of 187 home runs (11th in MLB).Phillies batting statsThe Phillies’ 210 home runs rank eighth in Major League Baseball.Hitters for Philadelphia rank third in the majors with a combined .434 team slugging percentage.The Phillies’ .260 batting average is among the best in baseball, ranking second in MLB.Philadelphia has scored 773 runs this season, which ranks seventh in MLB.The Phillies are among the best in the league at getting on base, ranking fourth with an OBP of .330.Philadelphia ranks 12th in MLB in strikeouts per game with an average of 8.2 whiffs per contest.Twins stats and trendsTwins betting recordsThe Twins have been chosen as underdogs in 68 games this year and have walked away with the win 27 times (39.7%) in those games.Minnesota has a mark of 5-10 in contests where bookmakers favor it by +142 or worse on the moneyline.The Twins have an implied victory probability of 41.3% according to the moneyline set by sportsbooks for this matchup.Minnesota and its opponents have gone over in 72 of its 158 games with a total set by sportsbooks this season.The Twins have an against the spread mark of 79-79-0 in 158 games with a line this season.Joe Ryan (Twins probable starter)Ryan gets the start for the Twins, his 30th of the season. He is 13-9 with a 3.47 ERA and 185 strikeouts in 166 2/3 innings pitched.His most recent appearance came on Saturday against the Cleveland Guardians, when the righty threw five innings, surrendering four earned runs while allowing six hits.In 30 games this season, the 29-year-old has an ERA of 3.47, with 10.0 strikeouts per nine innings. Opponents are hitting .218 against him.Ryan is trying to record his 15th quality start of the year in this game.Ryan heads into this game with 27 outings of five or more innings pitched this campaign.In five of his 30 total appearances this season he has not surrendered an earned run.The opposing Phillies offense has a collective .260 batting average, and is second in the league with 1409 total hits and seventh in MLB action with 773 runs scored. They have the third-ranked slugging percentage (.434) and are eighth in all of MLB with 210 home runs.Among qualifying pitchers in MLB play this season, the 29-year-old’s 3.47 ERA ranks 18th, 1.036 WHIP ranks 10th, and 10.0 K/9 ranks 10th.Twins batting statsThe Twins are 11th in MLB action with 187 home runs. They average 1.2 per game.This season, Minnesota is 16th in baseball with a .397 slugging percentage.The Twins have the 22nd-ranked batting average in the league (.239).Minnesota scores the 21st-most runs in baseball (671 total, 4.2 per game).The Twins’ .311 on-base percentage ranks 20th in baseball.