Royals vs. Athletics Prediction, Odds, Picks - September 26

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The Kansas City Royals and Athletics take the field on Friday at 10:05 p.m. ET. Vinnie Pasquantino and Nick Kurtz have been on a tear in recent games for their respective clubs. Bookmakers list the Royals as -116 moneyline favorites, while giving the underdog Athletics -104 moneyline odds to win. The Royals are a 1.5-run favorite (at +134 odds). The over/under is 10 runs for the matchup.

Take a look at everything you need from a betting perspective on the Royals-Athletics game, regarding the run line, moneyline and total, plus expert picks.

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Royals vs. Athletics Game Information & OddsWhen: Friday, September 26, 2025 at 10:05 p.m. ETWhere: Sutter Health Park in West Sacramento, CaliforniaHow to watch on TV: NBCS-CA and FDSKC Favorite Favorite Moneyline Underdog Moneyline Total Over Total Odds Under Total Odds Run Line Favorite Run Line Odds Underdog Run Line Odds Royals -116 -104 10 -120 +100 -1.5 +134 -161 Royals vs. Athletics PredictionScore Prediction: Athletics 6, Royals 5Total Prediction: Under 10 runsWin Probabilities: Royals 52%, Athletics 48%Royals vs. Athletics Betting InsightsThe Royals have won 39, or 58.2%, of the 67 games they’ve played as favorites this season.The Royals have a record of 35-25, a 58.3% win rate, when they’re favored by -116 or more by sportsbooks this season.The moneyline for this contest implies a 53.7% chance of a victory for the Royals.The Athletics have been underdogs in 119 games this season and have come away with the win 56 times (47.1%) in those contests.This season, the Athletics have come away with a win 49 times in 110 chances when named as an underdog of at least -104 or worse on the moneyline.Oddsmakers have implied with the moneyline set for this matchup that the Athletics have a 51% chance of pulling out a win.Royals Recent Betting PerformanceThe Royals were favored on the moneyline for four of their last 10 games, and they went 3-1 in those matchups.Over their last 10 outings — all had a set run total — the Royals and their opponents combined to hit the over on the total seven times.The Royals are 6-4-0 against the spread over their past 10 games.Royals Recent Stats Stat Avg/Total Record 6-4 Runs Per Game 6.8 HR 14 ERA 4.04 K/9 7.5 Royals Player InsightsBobby Witt Jr. paces the Royals with a .296 batting average.Including all MLB hitters, Witt is ninth in batting average, 36th in on-base percentage, and 16th in slugging.Pasquantino’s 32 home runs and 111 runs batted in are both team-highs.Among all major league hitters, Pasquantino ranks 16th in homers and fifth in RBI.Maikel Garcia is hitting .286 with 38 doubles, five triples, 16 home runs and 61 walks.Salvador Perez has 35 doubles, 30 home runs and 26 walks while batting .241.Royals Team Props Hits O/U Total Bases O/U HR O/U RBI O/U Salvador Pérez 0.5 (-265) 1.5 (-103) – 0.5 (+121) Mike Yastrzemski 0.5 (-247) 1.5 (+103) – 0.5 (+156) Adam Frazier 0.5 (-212) 1.5 (+151) – 0.5 (+214) Vinnie Pasquantino 1.5 (+191) 1.5 (-103) – 0.5 (+125) Maikel Garcia 1.5 (+194) 1.5 (+114) – 0.5 (+146) Athletics Recent Betting PerformanceIn seven games over the last 10 matchups when set as underdogs by oddsmakers, the Athletics had a record of 4-3.In their last 10 games with a total, the Athletics and their opponents have combined to hit the over three times.The Athletics have won six of their last 10 games against the spread.Athletics Recent Stats Stat Avg/Total Record 6-4 Runs Per Game 3.8 HR 11 ERA 3.58 K/9 7.0 Athletics Player InsightsBrent Rooker is batting .263 with 40 doubles, three triples, 30 home runs and 62 walks, while getting on base at a rate of .334.Rooker’s home run total puts him 25th in MLB, and he ranks 30th in RBI.Tyler Soderstrom has driven in the most runs for the Athletics with 93 runs batted in.Soderstrom is currently 46th in home runs and 22nd in RBI in the major leagues.Kurtz leads the Athletics with 35 long balls.Shea Langeliers has 30 doubles, 31 home runs and 36 walks while hitting .271.Athletics Team Props Hits O/U Total Bases O/U HR O/U RBI O/U Tyler Soderstrom 0.5 (-246) 1.5 (+120) – 0.5 (+162) Nick Kurtz 0.5 (-196) 1.5 (+120) – 0.5 (+146) Colby Thomas 0.5 (-195) 1.5 (+131) – 0.5 (+163) Brent Rooker 0.5 (-251) 1.5 (+103) – 0.5 (+134) Shea Langeliers 1.5 (+174) 1.5 (-116) – 0.5 (+141) Astros vs. Athletics Highlights | MLB on FOX