The Seattle Mariners and Toronto Blue Jays will face off in Game 6 of the American League Championship Series on Sunday. Seattle took a 3-2 series lead with a late-inning comeback win at home on Friday. They will try to close this series out and get to the World Series with a win on the road here. Before the first pitch is thrown in Toronto, continue reading to get my Mariners vs Blue Jays Game 6 prediction.

Our Mariners vs Blue Jays Game 6 PickPick: Seattle Mariners moneylineConfidence: ★★★☆☆Game SnapshotMatchup: Seattle Mariners vs Toronto Blue JaysDate & Time: Sunday, October 19, 2025, 8:03 PM ETStarting Pitchers: Trey Yesavage (TOR) vs Undecided (SEA)Stadium: Rogers Centre, Toronto, OntarioBroadcast: FS1 (U.S.) / Sportsnet (Canada)Key StorylinesPitching matchup

Toronto’s choice to start rookie Trey Yesavage while facing elimination in this game is a bold one. Yesavage has pitched 9.1 postseason innings, striking out 15 batters while allowing four hits and five earned runs. He is good at generating swings and misses but can give up hard contact when he fails to miss bats. Seattle has yet to decide on a starting pitcher for this game and how they approach this game will be a huge factor in determining whether they can close this series out.

Key Players

Seattle’s offense continues to lean on Cal Raleigh, who hit 60 home runs during the regular season and has been clutch in October. He tied Game 5 with a solo home run in the eighth inning on Friday. Eugenio Suárez remains a critical source of power after hitting two home runs in Game 5, including a game-winning grand slam in the eighth inning.

Vladimir Guerrero Jr. anchors the Toronto lineup and has come up big at the plate throughout the postseason. George Springer’s postseason experience and power have also been huge for the Jays, even as he manages a knee bruise sustained in Game 5 after getting hit by a pitch.

Best Player PropsPlayerProp TypePickCal RaleighHome RunsOver 0.5George SpringerTotal BasesOver 1.5Trey YesavageStrikeoutsUnder 5.5Betting Trends & H2HToronto holds a 6-5 lead in their season series against the Mariners.Three of the first five games of this series have gone over their respective totals.Game 5 snapped a nine-game streak between these teams where the road team got the win.Mariners vs Blue Jays Game 6 Model Projection

Score Projection: Seattle 4 – Toronto 3
Win Probability: Seattle 50%, Toronto 50%

Final Thoughts

This game is going to depend on the pitching on both sides. If Yesavage can pitch the way he did against the Yankees in his playoff debut, the Jays can force a Game 7. If Seattle’s starter can give them enough quality innings to build an early lead, Seattle could punch its ticket to the World Series without having to play a Game 7. I think we will see Seattle win Game 6 and move onto the World Series to face the Los Angeles Dodgers.

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