Check out the injury report for the San Francisco 49ers (5-3), which has 19 players (including Mac Jones), as the 49ers prepare for their matchup versus the New York Giants (2-6) at MetLife Stadium, on Sunday, Nov. 2 at 1 p.m. ET.
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49ers vs Giants TV channel & game infoGame day: Sunday, November 2, 2025Game time: 1 p.m. ETLocation: East Rutherford, New JerseyStadium: MetLife StadiumTV channel: CBSLive stream: Watch on Fubo! (Regional restrictions may apply)Live stream: Watch on Paramount+! (Regional restrictions may apply)
Watch San Francisco 49ers vs. New York Giants on Fubo! (Regional restrictions may apply)
49ers injury reportBryce Huff | DL (Out)Injury: HamstringPractice Status: Did Not Participate In Practice2025 Defensive Stats: 4.0 Sacks | 6.0 Tackles for Loss | 19 Tackles | 0 Interceptions | 1 Pass DefendedYetur Gross-Matos | DL (Out)Injury: KneePractice Status: Did Not Participate In PracticeRicky Pearsall | WR (Out)Injury: KneePractice Status: Did Not Participate In Practice2025 Receiving Stats: 29 Targets | 20 Receptions | 327 Yards | 0 TouchdownsJake Brendel | OL (Out)Injury: HamstringPractice Status: Did Not Participate In Practice2025 Season Stats: 3 Games PlayedBen Bartch | OL (Questionable)Injury: AnklePractice Status: Limited Participation in Practice2024 Season Stats: 1 Game PlayedJordan Elliott | DL (Questionable)Injury: AnklePractice Status: Did Not Participate In Practice2025 Defensive Stats: 0.0 Sacks | 1.0 Tackles for Loss | 16 Tackles | 0 Interceptions | 0 Passes DefendedSam Okuayinonu | DL (Questionable)Injury: AnklePractice Status: Limited Participation in Practice2025 Defensive Stats: 1.0 Sack | 2.0 Tackles for Loss | 21 Tackles | 0 Interceptions | 0 Passes DefendedSpencer Burford | OL (Questionable)Injury: KneePractice Status: Full Participation in PracticeBrock Purdy | QB (Questionable)Injury: ToePractice Status: Limited Participation in Practice2025 Passing: 73-for-48 | 586 Yards | 4 Touchdowns | 4 InterceptionsDee Winters | LB (Questionable)Injury: KneePractice Status: Limited Participation in Practice2025 Defensive Stats: 0.0 Sacks | 4.0 Tackles for Loss | 54 Tackles | 0 Interceptions | 3 Passes DefendedChristian McCaffrey | RBInjury: RestPractice Status: Full Participation in Practice2025 Rushing: 140 Attempts | 490 Yards | 3 Touchdowns2025 Receiving Stats: 74 Targets | 56 Receptions | 559 Yards | 3 TouchdownsUpton Stout | CBInjury: ShoulderPractice Status: Full Participation in Practice2025 Defensive Stats: 1.0 Sack | 2.0 Tackles for Loss | 34 Tackles | 0 Interceptions | 2 Passes DefendedJauan Jennings | WRInjury: AnklePractice Status: Full Participation in Practice2025 Receiving Stats: 36 Targets | 18 Receptions | 212 Yards | 1 TouchdownGeorge Kittle | TEInjury: ObliquePractice Status: Full Participation in PracticeAlfred Collins | DTInjury: ShoulderPractice Status: Full Participation in PracticeKalia Davis | DLInjury: HandPractice Status: Full Participation in PracticeKeion White | DLInjury: Nir – otherPractice Status: Limited Participation in PracticeTrent Williams | OTInjury: RestPractice Status: Full Participation in Practice2025 Season Stats: 3 Games PlayedMac Jones | QBInjury: KneePractice Status: Full Participation in Practice2025 Passing: 226-for-149 | 1,597 Yards | 8 Touchdowns | 5 Interceptions49ers insightsThe 49ers’ offense has seen declining production over its last three games, putting up 18.0 points per game, compared to its season-long average of 20.0 points per contest.Turning our attention to yardage, San Francisco has racked up fewer total yards per game over its past three matchups (303.3) than it has averaged for the season (348.6).In the passing game, the 49ers have seen a downtick in production over their last three games, piling up 207.0 passing yards per game, compared to their season-long average of 259.3 passing yards per contest.San Francisco is running for 89.4 yards per contest this season, but it has been a little better in the running game over its last three matchups, averaging 96.3 rushing yards per game.49ers vs Giants odds
NFL odds courtesy of BetMGM. Odds updated Saturday at 9:29 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Spread Favorite: 49ers (-2.5)Moneyline: 49ers (-145), Giants (+122)Total: 48.5 points
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