Christian McCaffrey and the San Francisco 49ers (5-3) face the New York Giants (2-6) on Sunday at 1 p.m. ET at MetLife Stadium.
The 49ers rank 13th in total offense (348.6 yards per game) and 22nd in total defense (337.1 yards allowed per game) this year. The Giants rank 22nd in the NFL with 21.6 points per contest on offense, and they rank 26th with 26.9 points ceded per game on the defensive side of the ball.
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49ers vs Giants: live streaming info, TV channel & game timeGame day: Sunday, November 2, 2025Game time: 1 p.m. ETLocation: East Rutherford, New JerseyStadium: MetLife StadiumTV channel: CBSLive stream: Watch on Fubo! (Regional restrictions may apply)Live stream: Watch on Paramount+! (Regional restrictions may apply)
Watch San Francisco 49ers vs. New York Giants on Fubo! (Regional restrictions may apply)
49ers vs Giants betting lines
NFL odds courtesy of BetMGM. Odds updated Sunday at 12:29 a.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Spread Favorite: 49ers (-2.5)Moneyline: 49ers (-145), Giants (+122)Total: 48.5 points
Watch San Francisco 49ers vs. New York Giants on Fubo! (Regional restrictions may apply)