(Editor’s note: This is excerpted from Mike Sando’s Pick Six of Nov. 10, 2025.)

4. Is baseball next for Kyler Murray? It’s hard to envision another NFL team giving up much for him, let alone assuring him a starting job.

The Cardinals’ decision to name Jacoby Brissett their starting quarterback (and later place Murray on injured reserve) didn’t matter in Week 10 against a red-hot Seahawks team in Seattle. Arizona might have lost that game with 2008 Kurt Warner at the offensive controls.

The QB switch matters very much in the big picture.

It’s clear the Arizona staff would rather bet its future on Brissett, a 32-year-old journeyman spot starter, than on Murray, the 2019 No. 1 draft choice earning seven times as much in annual salary. And for good reason.

“He gets the tight end (Trey McBride) more involved and clearly knows where to go with the football,” an opposing coach said. “The ball comes out quicker, the timing is better, everything.”

Brissett gives the Cardinals a chance to run their actual offense, which is heavy on under-center formations. The offense has also been more productive with him, even after the rough game at Seattle.

So, what’s next for Murray, who has $36.8 million in fully guaranteed salary next season? It seems unlikely the Cardinals would still have Murray on their roster on March 22, 2026, when $19.5 million in 2027 salary becomes fully guaranteed.

“I think they’re gonna have an awakening if they think they can get something for that kid somewhere else,” an exec from another team said.

Not that anyone would likely walk away from nearly $37 million, but would Murray even want to be a backup?

“Do you want him to be your backup in Cincinnati? In Pittsburgh?” another coach said. “These are completely different offenses. If you wanted to get your backup behind Lamar (Jackson), maybe? Is he done as a starter? It’s a fascinating question. Would Miami take him?”

Murray turns 29 before next season. The MLB’s Athletics own his baseball rights after using the ninth overall pick on him in 2018, before Murray had declared his intention to play football. The last time Murray played baseball, for the Oklahoma Sooners in 2018, he batted .296 with 10 home runs in 51 games as a centerfielder.

“Would the Jets consider him?” another exec asked. “He can go try baseball.”