Jonathan Aranda and the Tampa Bay Rays will hit the field on Wednesday at George M. Steinbrenner Field against Hunter Brown, who is projected to start for the Houston Astros. First pitch is at 1:10 p.m. ET.

The 9.4 strikeouts per nine innings compiled by the Astros pitching staff ranks third in the majors. The Rays rank 20th in MLB with a .241 team batting average.

Before the Astros vs. Rays matchup, here is what you need to get ready for Wednesday’s baseball action, including viewing options.

Astros vs. Rays: live stream info, TV channel & game timeGame day: Wednesday, May 21, 2025Game time: 1:10 p.m. ETLocation: Tampa, FloridaStadium: George M. Steinbrenner FieldTV channel: FanDuel Sports Network SunLive stream: Watch LIVE with Fubo! (Regional restrictions may apply)

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Astros vs. Rays odds & betting linesFavorite: Astros (-141, bet $141 to win $100)Underdog: Rays (+119, bet $100 to win $119)Over/under: 8.5

MLB odds courtesy of BetMGM Sportsbook. Odds updated Wednesday at 3:08 a.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.