The Chicago White Sox host the Seattle Mariners on Wednesday in MLB action.

Guaranteed Rate Field is set to host the exciting mid-week matchup between the Chicago White Sox and the Seattle Mariners on Wednesday in MLB regular season action. The Mariners headed into the week coming off of a three-game series against the San Diego Padres to wrap up the previous week of MLB action. Seattle paid a visit to Petco Park on Friday night to take on the Padres in San Diego for Game 1. The Mariners were able to take a 5-1 victory away from home thanks to runs from J.P. Crawford, Julio Rodríguez, Cal Raleigh (two) and Rowdy Tellez. Furthermore, Logan Evans got the start on the mound for Seattlein Game 1, where he gave up seven hits to go along with his three strikeouts on the night.

How to Watch Seattle Mariners at Chicago White Sox Today:

Game Date: Wednesday, May 21, 2025

Game Time: 2:00 p.m. ET

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TV Channel: Chicago Sports Network

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Then, Seattle was able to come away with another 4-1 victory in Game 2 at Petco Park on Saturday. This time, Raleigh scored another pair of runs to go along with scores from Randy Arozarena and Tellez.

Meanwhile, Emerson Hancock got the start in Game 2, going for just under five innings and giving up San Diego’s lone run in the bottom of the fourth.

Finally, the Mariners once again held the Padres to just one run in their 6-1 victory to close out the series at Petco Park on Sunday. Bryan Woo started and went for seven innings, where he struck out five San Diego batters.

Don’t miss the thrilling matchup between the White Sox and the Mariners on Wednesday in MLB action.

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