After seven seasons in the Marlins’ minor-league system, Mesa Jr. made his MLB debut in 2025. His time in the majors was brief and uneven. Across 16 games, he posted a .188 batting average with two doubles, one home run, and six RBI in 38 plate appearances. While those numbers failed to secure him a permanent role, they also came in a small sample size that never allowed him to settle into consistent playing time.