The Chicago White Sox (17-36) visit the New York Mets (32-21) Monday for the first game of a 3-game series. First pitch from Citi Field is at 4:10 p.m. ET (MLB Network). Let’s analyze BetMGM Sportsbook’s MLB odds around the White Sox vs. Mets odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting; Mets swept 3-0 in 2024

The White Sox have dropped 7 of their last 10 games but are coming off a home series win, taking 2 of 3 against the Texas Rangers. They lost the finale 5-4 Sunday after RP Jordan Leasure gave up 3 runs in the top of the ninth. C Edgar Quero had 3 hits in the loss.

The Mets have won 3 of their last 4 games after taking 2 of 3 at home against the LA Dodgers. They won the finale 3-1 Sunday, as SP Kodai Senga allowed 1 run over 5 1/3 innings and the bullpen followed with 3 2/3 scoreless frames. 1B Pete Alonso hit a 2-run homer — his 10th of the season — in the bottom of the first, providing all the offense New York needed.

White Sox at Mets projected starters

RHP Adrian Houser vs. RHP Clay Holmes

Houser (1-0, 0.00 ERA) makes his second start. He allowed 2 hits and 3 walks with 2 K’s in 6 scoreless innings in his debut, a 1-0 home win over the Seattle Mariners Tuesday.

2024 stats: 1-5, 5.84 ERA (69 1/3 IP, 45 ER), 1.53 WHIP, 5.8 K/9 in 7 starts and 16 relief appearances with MetsCareer vs. Mets: 1-1, 2.89 ERA (18 2/3 IP, 6 ER), 20 H, 3 BB, 11 K in 3 starts and 2 relief appearances — last faced them in 2023

Holmes (5-3, 3.13 ERA) makes his 11th start. He has a 1.24 WHIP, 3.3 BB/9 and 8.7 K/9 through 54 2/3 innings.

Last start: Loss, 6 IP, 2 ER, 4 H, 3 BB, 5 K in 2-0 defeat at Boston Red Sox last Tuesday2025 home stats: 2-1, 3.86 ERA (23 1/3 IP, 10 ER), 19 H, 9 BB, 25 K in 4 startsCareer vs. White Sox: 0-0, 0.00 ERA (7 IP), 2 H, 3 BB, 6 K in 7 relief appearances

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White Sox at Mets odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:05 a.m. ET.

Moneyline (ML): White Sox +240 (bet $100 to win $240) | Mets -300 (bet $300 to win $100)Run line (RL)/Against the spread (ATS): White Sox +2.5 (-135) | Mets -2.5 (+110)Over/Under (O/U): 8.5 (O: -102 | U: -118)White Sox at Mets picks and predictionsPrediction

Mets 4, White Sox 3

The Mets’ 19-6 home record is the best in the majors. Chicago’s 5-21 road mark is the second-worst in all of baseball.

Houser was fantastic in his first start of the year, but Holmes has allowed 2 or fewer runs in 7 of his 10 starts this season.

Expecting a White Sox win doesn’t make sense, and betting the Mets to win at -300 doesn’t give you enough value to make sense.

PASS.

The question is now whether you think it will be closer than 3 runs, as this game has a 2.5-run spread.

The White Sox’ last 2 losses have been by only 1 run, but their previous 5 were by more than 2 runs.

Four of the Mets’ last 6 wins have been by 1 or 2 runs, but 7 of their last 13 wins have been by 3 or more runs.

If Houser pitches similarly to how he fared in his first start of the year, this will be a close game.

BET WHITE SOX +2.5 (-135).

Eleven of the Mets’ last 13 games have not reached 9 total runs.

Three of the last 4 games for the Sox have had 9 or more total runs, but 13 of their last 19 have had 8 or fewer.

BET UNDER 8.5 (-118).

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