Brendan Donovan and the St. Louis Cardinals hit the field on Wednesday at Oriole Park at Camden Yards against Cade Povich, who gets the start for the Baltimore Orioles. First pitch is set for 6:35 p.m. ET.

The pitching staff for the Orioles has a collective 7.9 K/9, which ranks 24th in MLB. Cardinals pitchers have a combined ERA of 3.71 ERA this year, which ranks 12th in MLB.

Prepare for the Orioles vs. Cardinals with what you need to know ahead of Wednesday’s baseball action, including viewing options.

Orioles vs. Cardinals: live stream info, TV channel & game timeGame day: Wednesday, May 28, 2025Game time: 6:35 p.m. ETLocation: Baltimore, MarylandStadium: Oriole Park at Camden YardsTV channel: MASN (Baltimore)Live stream: Watch LIVE with Fubo! (Regional restrictions may apply)

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Orioles vs. Cardinals odds & betting linesFavorite: Orioles (-124, bet $124 to win $100)Underdog: Cardinals (+104, bet $100 to win $104)Over/under: 8.5

MLB odds courtesy of BetMGM Sportsbook. Odds updated Wednesday at 3:07 a.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.