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The Los Angeles Dodgers aim for a season-opening three-game sweep of their NL West counterpart, the Arizona Diamondbacks, in the series finale on Saturday night.
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Eduardo Rodriguez is slated to start for the visitors, and my Diamondbacks vs. Dodgers predictions and MLB picks foresee him doing his part in avoiding the sweep on Saturday, March 28.
Diamondbacks vs Dodgers predictionsDiamondbacks vs Dodgers best bet: Eduardo Rodriguez Over 3.5 strikeouts (+124)
After dropping the first two games of the series, the Arizona Diamondbacks could use a strong outing from Eduardo Rodriguez on Saturday.
The veteran southpaw isn’t known for his punchout prowess, but he’s had strikeout success against the Los Angeles Dodgers. Across a sample size of 131 at-bats vs. L.A.’s projected hitters, he’s racked up a respectable 26% K-rate.
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Rodriguez tossed 4+ strikeouts in 20 of his 29 starts last year, and was in fine form during the World Baseball Classic, throwing four scoreless against Team USA. Expect a successful start to the season for him.
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Arizona didn’t get much length from either Zac Gallen or Ryne Nelson, so Rodriguez may have a slightly longer leash than normal.
Diamondbacks vs Dodgers same-game parlay (SGP)
How about a pitcher’s delight?
Tyler Glasnow may be primed for a career year — if he can finally stay healthy — and looked dominant in his last outing, striking out 11 Angels in an exhibition start.
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The towering righty has maintained a K rate above 29% each of the last eight seasons and gets a favorable matchup against an Arizona lineup that has failed to launch, posting a 77 wRC+ and 29.4% K rate in games one and two.
L.A. has its best bullpen in years, which will lead to more low-scoring games in 2026 now that it provides an adequate pairing with the strong rotation.
Diamondbacks vs Dodgers SGP
Eduardo Rodriguez Over 3.5 strikeouts
Tyler Glasnow Over 6.5 strikeouts
Diamondbacks vs Dodgers home run pick: Teoscar Hernandez (+400)
Teoscar Hernandez has been quiet to start the year. That could change in game three, given that he’s had success against Rodriguez in the past, batting 10-for-26 with three home runs and a 1.293 OPS.
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The outfielder is posting strong underlying numbers early (.348 xBA and a 74th percentile bat speed). He’s mashed lefties in his career (136 wRC+), which will play against Rodriguez, who surrendered 1.57 HR/9 to right-handed bats in 2025.
2026 Transparency record
Best bets: 1-0, +1.45 units
Diamondbacks vs Dodgers odds
Moneyline: Arizona +200 | Los Angeles -240
Run line: Arizona +1.5 | Los Angeles -1.5
Over/Under: Over 9 | Under 9
Diamondbacks vs Dodgers trend
Eduardo Rodriguez has gone Over 3.5 strikeouts in 23 of his last 33 outings. Find more MLB betting trends for Diamondbacks vs. Dodgers.
How to watch Diamondbacks vs Dodgers and game info
Location
Dodger Stadium, Los Angeles, CA
Date
Saturday, March 28, 2026
First pitch
9:10 p.m. ET
TV
Dbacks TV, SportsNet LA
Diamondbacks starting pitcher
Eduardo Rodriguez
(2025: 9-9, 5.02 ERA)
Dodgers starting pitcher
Tyler Glasnow
(2025: 4-3, 3.19 ERA)
Diamondbacks vs Dodgers latest injuriesDiamondbacks vs Dodgers weather
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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