The Mariners made a run at a comeback with Luke Raley smashing a two-run homer to deep right-center off right-hander Connor Brogdon. Raley’s third homer in three games cut the deficit to one run.

But it wasn’t enough.

Brogdon struck out Leo Rivas and Cole Young to end the game.

“Tough one tonight,” manager Dan Wilson said. “A one-run loss is always tough. Extra innings makes it a little more difficult. But you’ve got to give it to our guys, they came back there in the ninth inning and battled to get the tie, and then making it exciting there in the bottom of the 10th as well. We kept coming back and that’s what this team is all about. But just a little bit too late and a little bit short.”

The Mariners wasted a quality start from Bryan Woo. Though he was less than pleased with it in the end.

Woo dominated for the first five innings, allowing just two base runners — a second-inning bloop single to David Fry and a one-out double to Angel Martinez in the fifth — while striking out seven.

But in the sixth, pitching with a 2-0 lead, Woo created his own problems, walking the No. 9 hitter Rocchio to start the inning. But he came back to retire the next two batters he faced, getting Kwan to fly out to center and striking out DeLauter for the second time in the game.

That third out wouldn’t come immediately.

Woo fell behind 2-0 and 3-1 to José Ramírez, who took advantage of a low fastball on the inside corner, lining it into the right field corner for a double that scored Rocchio. Ramírez, who advanced to third on the throw home, scored moments later when Kyle Manzardo — a former Washington State star — dumped a first-pitch fastball into right field for game-tying single.

“Just undisciplined, I guess is the best way I can put it,” Woo said of the sixth. “I’ve got to be better about coming out, especially as I get later in the games, you got to up your focus even more. That just can’t happen.”

Woo would finish the inning, striking out Fry, but he was clearly irritated as he walked off the mound. His final line: six innings pitched, two runs allowed on four hits with a walk and nine strikeouts.

“Even though a lot of things took place, I still feel like this game was on me,” Woo said. “I feel like if I do my job and limit the damage, even if I just give up one in that inning, you still get out of it with a lead. When you’ve got a team down like that, you’ve got to keep them down, especially just a scrappy team like that, you can’t give them any breath of life. I’ve got to do better job.”

The Guardians took the lead an inning later. Eduard Bazardo retired the first two batters he faced, but then proceeded to walk C.J. Kayfus and Rocchio, who was down 0-2 in the count.

Wilson opted to stay with Bazardo to face the left-handed hitting Kwan despite having Gabe Speier up and ready in the bullpen. Kwan was hitless in three prior plate appearances against Speier with two strikeouts.

Kwan singled to left field to drive in the go-ahead run as Speier stood on the bullpen mound and watched. He would enter after the Kwan hit and retire DeLauter to end the inning.

“Zardo is a guy we really trust,” Wilson said. “You are hoping you can get him through there and Gabe would have the next inning.”

Wilson admitted there were multiple relievers unavailable to pitch.

“There were a couple of guys that needed a little bit of rest,” he said. “You have to weigh all those factors especially early in the season and understand that it’s a long year. Some guys need a little more rest and some don’t.”