Guardians vs Mariners Prop Picks & Best Bets for Sunday Night Baseball

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The first iteration of Sunday Night Baseball for the 2026 season goes down tonight between the Cleveland Guardians and Seattle Mariners at 7:20 p.m. ET on Peacock.

Can star slugger Jose Ramirez and red-hot rookie Chase DeLauter take advantage of an advantageous pitching matchup? How about Slade Cecconi’s strikeout prop against a whiff-heavy Mariners squad?

I answer those questions with my Guardians vs. Mariners predictions and MLB picks for SNB on March 29.

Guardians vs Mariners props for March 29

Pick

Odds

Jose Ramirez Over 1.5 total bases

+100

Slade Cecconi Over 4.5 strikeouts

-112

Chase DeLauter home run

+450

Guardians vs Mariners player prop picksJose Ramirez Over 1.5 total bases (+100)

Emerson Hancock gets the nod for the Seattle Mariners, and that’s more about the injuries around him than it is his personal brilliance.

The tall righty has managed poor results with a 5.49 xERA and 5.23 FIP across 162 2/3 innings despite playing in the pitcher’s haven that is T-Mobile Park.

The former Georgia Bulldog pitches to contact with a lowly 16.6% K rate, and those balls-in-play have a high likelihood of falling for hits given his second-percentile xBA (.291).

Jose Ramirez demolished right-handed pitching a year ago (143 wRC+) and has strong numbers against four-seamers, sinkers, and changeups — Hancock’s hittable three-pitch arsenal against left-handed bats.

Slade Cecconi Over 4.5 strikeouts (-112)

The Seattle Mariners have some worrisome contact data at the plate through three games, leading to an increased expectation for Cleveland Guardians starter Slade Cecconi’s strikeout numbers.

They have the worst zone-contact percentage (74.6%) in the league, which has led to a 32.1% K rate. Tanner Bibee, Gavin Williams, and Joey Cantillo all managed to find swings and misses against this lineup, and now it’s Cecconi’s turn.

The 26-year-old was sharp in the spring, tossing a 1.62 ERA across 16 2/3 frames. He’s riding a nine-inning scoreless streak and has found success adding a sweeper and tightening his cutter. The new arsenal should pay immediate dividends before hitters can adjust.

Chase DeLauter home run (+450)

Do you know who leads Major League Baseball in home runs entering Sunday?

It’s Cleveland rookie Chase DeLauter with four, who has homered in each of his first three regular-season games — including last night’s game-winning dinger in the 10th inning.

The ballyhood prospect has lived up to the hype and more, and a case can be made that he’s the league’s hottest hitter given his .357/.357/.1.214 slash line.

There’s been a lot of swing-and-miss in his game (35.7%), but Hancock’s unimpressive strikeout abilities diminish that concern. If DeLauter makes contact, look out.

How to watch Guardians vs Mariners and game info

Location

T-Mobile Park, Seattle, WA

Date

Sunday, March 29, 2026

First pitch

7:20 p.m. ET

Peacock

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Guardians vs Mariners Prop Picks & Best Bets for Sunday Night Baseball

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