The Cardinals are -110 favorites vs the Nationals

Cardinals vs Nationals Over / Under today: 7.5 Runs

Cardinals / Nationals TV Channel: CATV | NATV

The St. Louis Cardinals (-110) visit Nationals Park to take on the Washington Nationals (-110) on April 7, 2026. First pitch is scheduled for 6:45 pm in Washington, DC.

This season, the Cardinals are 5-5 against the spread (ATS), while the Nationals are 6-4 ATS.

Cardinals vs Nationals Starting Pitchers Today:

Cardinals starting pitcher: Matthew Liberatore 0-0, 1.64 ERA

Nationals starting pitcher: Cade Cavalli 0-0, 3.00 ERA

Cardinals vs. Nationals Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneylineCardinals-1.5 +155O 7.5 -110-110Nationals +1.5 -190U 7.5 -110-110

Based on recent trends the model predicts the Nationals will win Tuesday‘s MLB game with 51.0% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

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We’ve highlighted some favorite MLB player prop bets for Cardinals players for Tuesday‘s game, looking at profitable historical betting trends:

Best Cardinals Player Prop Bets Today:

Matthew Liberatore has hit the Walks Allowed Over in 6 of his last 8 away games (+5.25 Units / 64% ROI)

Matthew Liberatore has hit the Hits Allowed Under in 10 of his last 15 games (+4.95 Units / 27% ROI)

Matthew Liberatore has hit the Earned Runs Under in his last 4 games (+4.30 Units / 83% ROI)

Matthew Liberatore has hit the Pitching Outs Over in his last 4 games (+4.15 Units / 73% ROI)

Pedro Pages has hit the Home Runs Over in 1 of his last 5 games (+4.00 Units / 80% ROI)

And here are some favorite MLB player prop bets for Nationals players for Tuesday‘s game, looking at profitable historical betting trends:

Best Nationals Player Prop Best Bets Today:

Joey Wiemer has hit the Home Runs Over in 3 of his last 9 games (+15.10 Units / 168% ROI)

Curtis Mead has hit the Total Bases Over in 7 of his last 8 games at home (+5.60 Units / 48% ROI)

Curtis Mead has hit the Hits Runs and RBIs Over in 6 of his last 7 games at home (+5.20 Units / 53% ROI)

Curtis Mead has hit the Hits Over in 7 of his last 8 games at home (+5.20 Units / 42% ROI)

Curtis Mead has hit the Singles Under in 8 of his last 10 games (+5.00 Units / 38% ROI)

Cardinals Best Bets Today:

The St. Louis Cardinals have hit the Team Total Under in 46 of their last 77 games (+10.70 Units / 12% ROI)

The St. Louis Cardinals have hit the 1st Five Innings (F5) Team Total Under in 64 of their last 113 games (+9.25 Units / 7% ROI)

The St. Louis Cardinals have hit the Game Total Over in 21 of their last 36 away games (+6.65 Units / 17% ROI)

The St. Louis Cardinals have hit the 1st Five Innings (F5) Moneyline in 9 of their last 19 games (+1.30 Units / 6% ROI)

The St. Louis Cardinals have covered the Run Line in 36 of their last 67 away games (+0.85 Units / 1% ROI)

Nationals Best Bets Today:

The Washington Nationals have hit the 1st Five Innings (F5) Team Total Under in 42 of their last 68 games at home (+13.72 Units / 17% ROI)

The Washington Nationals have hit the Team Total Under in 39 of their last 62 games at home (+13.30 Units / 18% ROI)

The Washington Nationals have hit the Game Total Over in 48 of their last 87 games (+12.05 Units / 12% ROI)

The Washington Nationals have hit the Moneyline in 13 of their last 26 games (+5.00 Units / 18% ROI)

The Washington Nationals have covered the 1st Five Innings (F5) Run Line in 15 of their last 26 games (+3.35 Units / 11% ROI)

Cardinals Against the Spread (ATS) Record

Against the spread this season, the Cardinals are 5-5 against the Run Line (-0.85 Units / -6.34% ROI).

5-5 when betting on the Moneyline for +2.05 Units / 22.65% ROI

5-4 when betting on the total runs Over for -0.4 Units / -4.1% ROI

4-5 when betting on the total runs Under for -0.55 Units / -5.47% ROI

Nationals Against the Spread (ATS) Record

Against the spread this season, the Nationals are 6-4 against the Run Line (+0.9 Units / 8.96% ROI).

4-6 when betting on the Moneyline for -0.65 Units / -7.22% ROI

8-2 when betting on the total runs Over for +4.85 Units / 49.49% ROI

2-8 when betting on the total runs Under for -5.75 Units / -57.5% ROI

Cardinals Keys to the Game vs. the Nationals

The Cardinals are 131-8 (.942) when leading entering the 8th inning since the 2024 season — 4th best in MLB; League Avg: .904.

The Cardinals are just 8-12 (.400) when tied entering the 8th inning since the 2025 season — tied for 5th lowest in MLB; League Avg: .500.

The Cardinals were just 7-11 (.389) when tied entering the 8th inning in the 2025 season — tied for 5th lowest in MLB; League Avg: .500.

The Cardinals are 28-18 (.609) when tied entering the 7th inning since the 2024 season — tied for 4th best in MLB; League Avg: .499.

Nationals Keys to the Game vs. the Cardinals

The Nationals were just 31-49 (.383) at home in the 2025 season — 2nd lowest in MLB; League Avg: .542.

The Nationals were just 65-96 (.401) in the 2025 season — 3rd lowest in MLB; League Avg: .500.

The Nationals are just 32-52 (.376) at home since the 2025 season — 2nd lowest in MLB; League Avg: .543.

The Nationals are just 11-45 (.193) when their opponents score in the first inning since the 2025 season — lowest in MLB; League Avg: .359.

Cardinals Hitting Stats & Trends

Cardinals hitters have struck out in just 16% of their PA’s against LHP this season — 5th best in MLB.

Cardinals hitters have chased 24% of pitches out of the zone against LHP this season — 2nd lowest in MLB.

Cardinals hitters are slugging just .482 with the pitcher behind in the count since the 2025 season — lowest in MLB.

Cardinals hitters have an OPS of just .937 (1,244 PA’s) with the pitcher behind in the count since the 2025 season — 2nd lowest in MLB.

Nationals Hitting Stats & Trends

The Nationals have scored 34 runs with two outs this season — 3rd most in MLB.

Nationals hitters have struck out in just 19% of their PA’s against RHP this season — tied for 4th best in MLB.

Nationals hitters are slugging .458 this season — 3rd best in MLB.

Nationals hitters are slugging .467 against RHP this season — tied for 4th best in MLB.

Cardinals Pitching Stats & Trends

Opponents have a miss rate of just 19% against Cardinals pitchers this season — lowest in MLB.

Cardinals pitchers have a strikeout rate of just 31% with two-strikes this season — lowest in MLB.

Cardinals pitchers had a strikeout rate of just 20% in the 2025 season — 2nd lowest in MLB.

Cardinals pitchers have a strikeout rate of just 14% this season — lowest in MLB.

Nationals Pitching Stats & Trends

Nationals pitchers have an ERA of 9.25 (36.0 IP) at home this season — highest in MLB.

The Nationals allowed 1.85 runs per game (299/162) in late innings in the 2025 season — highest in MLB.

Nationals pitchers had an ERA of 5.34 (1424.2 IP) in the 2025 season — 2nd highest in MLB.

The Nationals have allowed 9.25 runs per game (37/4) at home this season — highest in MLB.

More MLB Reading:

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