The Pirates are -160 favorites vs the Padres

Padres vs Pirates Over / Under today: 6.5 Runs

Padres / Pirates TV Channel: PDTV | SNPT

The San Diego Padres (+135) visit PNC Park to take on the Pittsburgh Pirates (-160) on April 7, 2026. First pitch is scheduled for 6:40 pm in Pittsburgh, PA.

This season, the Padres are 5-5 against the spread (ATS), while the Pirates are 6-4 ATS.

Padres vs Pirates Starting Pitchers Today:

Padres starting pitcher: Nick Pivetta 1-1, 6.76 ERA

Pirates starting pitcher: Paul Skenes 1-1, 9.54 ERA

Padres vs. Pirates Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneylinePadres+1.5 -185O 6.5 -115+135Pirates -1.5 +150U 6.5 -105-160

Based on recent trends the model predicts the Pirates will win Tuesday‘s MLB game with 59.6% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Padres vs Pirates and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Padres players for Tuesday‘s game, looking at profitable historical betting trends:

Best Padres Player Prop Bets Today:

Nick Pivetta has hit the Strikeouts Under in 6 of his last 7 away games (+5.35 Units / 67% ROI)

Nick Pivetta has hit the Hits Allowed Under in 13 of his last 20 games (+5.30 Units / 23% ROI)

Nick Pivetta has hit the Walks Allowed Under in 8 of his last 10 away games (+5.05 Units / 40% ROI)

Nick Pivetta has hit the Pitching Outs Over in 8 of his last 10 away games (+4.90 Units / 35% ROI)

Nick Pivetta has hit the Earned Runs Under in 13 of his last 20 games (+4.60 Units / 18% ROI)

And here are some favorite MLB player prop bets for Pirates players for Tuesday‘s game, looking at profitable historical betting trends:

Best Pirates Player Prop Best Bets Today:

Paul Skenes has hit the Walks Allowed Under in 12 of his last 15 games at home (+8.30 Units / 37% ROI)

Paul Skenes has hit the Earned Runs Under in 17 of his last 25 games (+8.10 Units / 27% ROI)

Paul Skenes has hit the Hits Allowed Over in 12 of his last 20 games (+3.40 Units / 13% ROI)

Paul Skenes has hit the Strikeouts Under in 3 of his last 4 games (+2.00 Units / 42% ROI)

Padres Best Bets Today:

The San Diego Padres have hit the Game Total Under in 86 of their last 151 games (+17.30 Units / 10% ROI)

The San Diego Padres have hit the 1st Five Innings (F5) Team Total Under in 41 of their last 64 away games (+15.75 Units / 21% ROI)

The San Diego Padres have hit the Team Total Under in 49 of their last 80 away games (+13.25 Units / 14% ROI)

The San Diego Padres have covered the Run Line in 41 of their last 73 games (+7.00 Units / 7% ROI)

The San Diego Padres have hit the Moneyline in 8 of their last 11 games (+4.65 Units / 32% ROI)

Pirates Best Bets Today:

The Pittsburgh Pirates have hit the Game Total Under in 88 of their last 150 games (+27.90 Units / 17% ROI)

The Pittsburgh Pirates have hit the Team Total Under in 92 of their last 151 games (+26.80 Units / 15% ROI)

The Pittsburgh Pirates have covered the Run Line in 77 of their last 124 games (+24.60 Units / 15% ROI)

The Pittsburgh Pirates have hit the 1st Five Innings (F5) Moneyline in 30 of their last 62 games at home (+14.29 Units / 18% ROI)

The Pittsburgh Pirates have hit the Moneyline in 37 of their last 62 games at home (+13.10 Units / 18% ROI)

Padres Against the Spread (ATS) Record

Against the spread this season, the Padres are 5-4 against the Run Line (-1.65 Units / -12.18% ROI).

5-5 when betting on the Moneyline for -0.95 Units / -9.41% ROI

3-6 when betting on the total runs Over for -2.45 Units / -24.87% ROI

6-3 when betting on the total runs Under for +1.7 Units / 17.09% ROI

Pirates Against the Spread (ATS) Record

Against the spread this season, the Pirates are 6-4 against the Run Line (+2.3 Units / 18.62% ROI).

6-4 when betting on the Moneyline for +3.6 Units / 36.18% ROI

5-5 when betting on the total runs Over for +0.65 Units / 6.7% ROI

5-5 when betting on the total runs Under for -1.65 Units / -16.34% ROI

Padres Keys to the Game vs. the Pirates

The Padres were 25-6 (.806) when they hit 2 or more home runs in the 2025 season — 5th best in MLB; League Avg: .699.

The Padres are 68-6 (.919) when leading entering the 7th inning since the 2025 season — 5th best in MLB; League Avg: .877.

The Padres are 26-18 (.591) vs the top 10 runs allowed teams since the 2025 season Today, they face Pirates (12th in runs allowed).

The Padres were 63-5 (.926) when leading entering the 7th inning in the 2025 season — 4th best in MLB; League Avg: .875.

Pirates Keys to the Game vs. the Padres

The Pirates were just 13-24 (.351) vs bottom 10 scoring offenses in the 2025 season Today, they face the Padres (28th in runs scored).

The Pirates are just 15-26 (.366) vs bottom 10 scoring offenses since the 2025 season Today, they face the Padres (27th in runs scored).

The Pirates were just 1-80 (.012) when trailing entering the 9th inning in the 2025 season — 2nd lowest in MLB; League Avg: .043.

The Pirates were just 6-50 (.107) when they allowed 5 or more runs in the 2025 season — 2nd lowest in MLB; League Avg: .202.

Padres Hitting Stats & Trends

Padres hitters struck out in just 18% of their PA’s against LHP in the 2025 season — best in MLB.

Padres hitters have struck out in just 19% of their PA’s against LHP since the 2025 season — tied for 2nd best in MLB.

Padres hitters have a groundball batting average of just .133 this season — lowest in MLB.

Padres hitters have struck out in just 18% of their PA’s against LHP since the 2024 season — best in MLB.

Pirates Hitting Stats & Trends

Pirates hitters had an OPS of just .622 (3,034 PA’s) on the road in the 2025 season — 2nd lowest in MLB.

Pirates hitters slugged just .333 on the road in the 2025 season — 2nd lowest in MLB.

Pirates hitters are slugging just .341 against LHP since the 2025 season — lowest in MLB.

Pirates hitters are slugging just .159 on pitches out of the zone since the 2025 season — lowest in MLB.

Padres Pitching Stats & Trends

Padres pitchers had a strikeout rate of 45% with two-strikes in the 2025 season — 4th best in MLB.

Padres pitchers had a strikeout rate of 24% in the 2025 season — tied for 4th best in MLB.

The Padres allowed 1.04 runs per game (168/162) in late innings in the 2025 season — 2nd best in MLB.

The Padres pitchers have allowed an average Exit Velocity of just 88.4 MPH since the 2023 season (11,978 balls in play) — best in MLB

Pirates Pitching Stats & Trends

Pirates pitchers have walked 21% of batters when facing the leadoff batter in the inning this season — highest in MLB.

Pirates pitchers walked 7% of batters when facing the leadoff batter in the inning in the 2025 season — 5th best in MLB.

Pirates pitchers have a strikeout rate of 38% in late innings this season — best in MLB.

Pirates pitchers have walked 13% of batters this season — 4th highest in MLB.

More MLB Reading:

Bet now on Padres vs Pirates and all games with BetMGM

Bet on MLB Odds at BetMGM

Sportsbook promos are always available at BetMGM. For new customers, check out the sportsbook welcome offer and BetMGM Refer a Friend. For existing customers, there are Odds Boosts, Parlay Boosts, contests and more.