Odds updated as of 9:11 p.m.

The Chicago Cubs are among the MLB teams busy on Friday, up against the Pittsburgh Pirates.

Before checking out the MLB betting lines on FanDuel Sportsbook, we’ve got you covered, in terms of the vital info about this game.

Chicago Cubs (6-6) vs. Pittsburgh Pirates (7-5)Date: Friday, April 10, 2026Time: 2:20 p.m. ETVenue: Wrigley Field — Chicago, IllinoisCoverage: MARQ and SportsNet PTAll MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.Moneyline: CHC: (-148) | PIT: (+126)Spread: CHC: -1.5 (+155) | PIT: +1.5 (-188)Total: 6.5 — Over: (-120) | Under: (-102)Cubs vs Pirates Probable Starting Pitchers

Probable Pitchers: Shota Imanaga (Cubs) – 0-1, 4.50 ERA vs Carmen Mlodzinski (Pirates) – 0-0, 4.00 ERA

The Cubs will give the ball to Shota Imanaga (0-1, 4.50 ERA), who is eyeing win No. 1 on the season, and the Pirates will counter with Carmen Mlodzinski. Imanaga has a record of 0-2-0 ATS in two starts with a spread this season. Imanaga’s team is 0-2 this season when he starts and they’re favored on the moneyline. Mlodzinski has started two games with set spreads, and the Pirates covered in both opportunities. The Pirates were named the moneyline underdog for one Mlodzinski start this season — they won.

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cubs win (54.8%)

Looking at the moneyline for Cubs-Pirates, Chicago is the favorite at -148, and Pittsburgh is +126 playing on the road.The Cubs are hosting the Pirates and are favored by 1.5 runs on the spread. The Cubs are +155 to cover the runline, with the Pirates being -188.The over/under for the Cubs versus Pirates contest on April 10 has been set at 6.5, with -120 odds on the over and -102 odds on the under.

Bet on Chicago Cubs vs. Pittsburgh Pirates on FanDuel today!

The Cubs have been victorious in four of the nine contests they have been chosen as favorites in this season.Chicago has a record of 3-2 when favored by -148 or more this year.The Cubs and their opponents have hit the over in six of their 12 games with a total set by oddsmakers this season.In 12 games with a line this season, the Cubs have a mark of 5-7-0 against the spread.The Pirates are 2-4 in games they were the underdog on the moneyline (winning 33.3% of those games).Pittsburgh has played as a moneyline underdog of +126 or longer in just two games this season, which it split 1-1.The Pirates have played in 12 games with an over/under set, and have combined with their opponents to go over the total seven times (7-5-0).The Pirates have a 7-5-0 record against the spread this season (covering 58.3% of the time).Cubs Player LeadersNico Hoerner leads Chicago with an OBP of .453, plus a team-best slugging percentage of .548. He’s batting .333 on the season.Among qualified batters in baseball, he is 15th in batting average, eighth in on-base percentage, and 29th in slugging.Hoerner will look for his fifth straight game with a hit in this contest. In his last five games he is batting .389 with two doubles, a home run, three walks and six RBIs.Ian Happ has eight hits, which is best among Chicago batters this season. He’s batting .200 with six extra-base hits. He’s also slugging .550 with an on-base percentage of .289.His batting average ranks 130th among qualified players, his on-base percentage 125th, and his slugging percentage 28th.Happ heads into this game looking to extend his two-game hit streak. In his last five games he is batting .190 with two doubles, a home run, a walk and two RBIs.Matt Shaw is batting .257 with a .457 slugging percentage and six RBI this year.Shaw brings a four-game hitting streak into this matchup. During his last five outings he is batting .294 with a double, two home runs, two walks and three RBIs.Alex Bregman is batting .188 with a .278 OBP and three RBI for Chicago this season.Pirates Player LeadersRyan O’Hearn has totaled 14 hits with a .449 on-base percentage and a .625 slugging percentage, all club-highs for the Pirates. He’s batting .350.Including all qualified hitters in MLB, he is 10th in batting average, 10th in on-base percentage and 12th in slugging percentage.Oneil Cruz’s .583 slugging percentage leads his team. He has a batting average of .292 with an on-base percentage of .333.Including all qualifying hitters, his batting average places him 39th, his on-base percentage ranks 73rd, and he is 17th in slugging.Bryan Reynolds is hitting .244 with a double, two home runs and eight walks.Brandon Lowe is batting .220 with two doubles, three home runs and seven walks.

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!