Keagan Smith gives you a preview, prediction and pick for today’s game between the Houston Astros and Seattle Mariners on Friday’s MLB slate.

The young MLB season continues as we turn early blips on the radar into real, meaningful statistical analysis. Pro baseball’s pecking order is coming into focus slowly but surely, and a matchup on Friday may give an intriguing glimpse into the AL West battle. The Houston Astros (6-7) can hit but can’t pitch… the Seattle Mariners (4-9) can throw but can’t put the bat to the ball. Which side comes out on top in this series opener?

Here’s a betting prediction and pick for tonight’s Astros vs. Mariners matchup courtesy of MLB odds and lines on DraftKings Sportsbook.

Astros vs. Mariners prediction, preview

Houston Astros

So, you’re the Astros and just dropped four straight games, including three straight losses to the Colorado Rockies. With injuries in the rotation and bullpen alike, it’ll be up to the bats to carry this team for a bit. They’re thankfully capable from early signs, logging the second-best OPS in the MLB at .825 to this point behind a strong .271/.371/.453 slash line — that OBP paces the Majors. A .182 ISO is also good for second, with the team tops in the sport with 34 doubles and third in homers with 16. Seems like a recipe for success, yeah? Not so fast. The pitching staff’s 6.05 ERA is the second worst of any team, as is their 1.59 WHIP. They’ve been especially vulnerable to the long ball with a 1.59 HR/9 and control issues are a mainstay already with the second-highest BB% at 13.7%.

Seattle Mariners

These Mariners had bats which crushed down the stretch last year, but they’re yet to show up in 2026. Somehow, Seattle sits dead last in the AL West after winning the division last season (yes, it’s early, we know) and holds the worst OPS in baseball thanks to a .581 mark. The M’s are the only team below .600, and a .184 AVG makes then the lowest team in the MLB in that stat as well (to go along with a .280 OBP and .301 SLG). The early results have been brutal with Julio Rodriguez, Cal Raleigh and Josh Naylor all at or below a .481 OPS. With a .118 ISO, there’s also a lack of extra bases thus far despite having a respectable 11 homers. In inverse fashion to Houston, though, the Mariners’ arms are exceptional. A staff ERA of 2.62 sits third, an 0.95 WHIP is good for second and a 20.8% K-BB% ranks first among the entire sport. Is it a blip? Probably not, especially with a 2.82 FIP as well.

Tonight’s starting pitchers

Houston trots out RHP Tatsuya Imai for his third-ever MLB start. His first was one to forget, but he shoved over the course of 5.2 scoreless innings with nine strikeouts in his most recent appearance. The movement profile on his pitches is plain absurd with a wrong-way slider that travels in the opposite direction off his hand. Now, he looks to improve on his 4.32 ERA and 1.56 WHIP, though striking out batters has been no issue with 13 Ks in 8.1 IP.

Seattle deploys another RHP, Emerson Hancock. His 2025 was unspectacular with a 4.90 ERA and 1.38 WHIP, starting 16 of his 22 total appearances. However, he’s at an 0.71 ERA and 0.55 WHIP through his first two starts (12.2 IP) this season, punching out 14 hitters. After throwing six scoreless innings without allowing a hit while striking out nine in his first go, then allowing just one earned run in his second, he may be energized heading into tonight.

Astros vs. Mariners pick, best bet

DraftKings Sportsbook lists the Mariners as -143 ML favorites at home. The Astros are behind at +119 odds to win outright. The run total sits at an even eight combined runs between these sides.

Best Bet: Tatsuya Imai 6+ strikeouts (-119)

The two starts we’ve seen from Imai couldn’t have been more different from each other in terms of overall performance. There is a common thread, however. While the Japanese transfer’s control may not be the best in baseball, he does have stuff. He’s got a ton of it, too, recording a 94th-percentile whiff rate (41.0%) and 91st-percentile K% (35.1%) through his pair of appearances. Let’s be so serious about this guy. Shoutout to Baseball Savant for the movement profile graphic below. Take a look at that and tell me why a Mariners lineup with the fourth-highest K% at 27.6% and highest whiff rate at 32.9% won’t take plenty of hacks tonight. I’m very bullish on at least six punchouts for Imai here.