Milwaukee Brewers right-hander Jacob Misiorowski exited Wednesday night’s start against the San Diego Padres early, creating immediate concern for one of the club’s top pitchers during a key National League matchup. The 24-year-old had been dominant at American Family Field before departing, striking out 10 batters across seven scoreless innings while repeatedly hitting triple digits with his fastball.

Misiorowski entered the game with a 2.45 ERA and a National League-leading 70 strikeouts, continuing his emergence as one of the Brewers’ most important arms. Following the game, Brewers manager Pat Murphy provided an initial update on the reason behind the early exit. Milwaukee Journal Sentinel reporter Curt Hogg shared the update on X, formerly Twitter, after Brewers manager Pat Murphy addressed the reason for Misiorowski’s early exit.

“Quad cramps for Misiorowski, Pat Murphy said.”

Quad cramps for Misiorowski, Pat Murphy said.

— Curt Hogg (@CyrtHogg) May 14, 2026

The following story is in development and will be updated shortly.

Milwaukee Brewers right-hander Jacob Misiorowski exited Wednesday night’s start against the San Diego Padres early, creating immediate concern for one of the club’s top pitchers during a key National League matchup. The 24-year-old had been dominant at American Family Field before departing, striking out 10 batters across seven scoreless innings while repeatedly hitting triple digits with his fastball.