The Washington Nationals (28-31) will host the Chicago Cubs (37-22), Tuesday at 6:45 p.m. ET, in the first game of a three-game series.

The Cubs are a favorite (-143) against the Nationals (+121). The matchup on the mound for this contest is set with the Chicago Cubs looking to Cade Horton (2-0), and Trevor Williams (3-5) taking the ball for the Washington Nationals.

The Cubs beat the Reds by a 7-3 score in their last game Sunday. Michael Busch went 2 for 2 with a home run and three RBIs to lead them offensively while Jameson Taillon picked up the win after throwing 6 1/3 innings, giving up two earned runs on three hits while striking out two.

The Nationals were defeated by the Diamondbacks 3-1 Sunday. Nathaniel Lowe went 1 for 4 with an RBI in the defeat, while Mitchell Parker took the loss on the mound, throwing five innings, giving up three earned runs on three hits while striking out two.

Here is everything you need to get ready for Tuesday’s Cubs vs. Nationals action, including viewing options.

Chicago Cubs vs. Washington Nationals odds, line and spread

MLB odds courtesy of BetMGM Sportsbook. Odds updated Monday at 3:20 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.

Favorite: Cubs (-143, bet $143 to win $100)Underdog: Nationals (+121, bet $100 to win $121)Over/under: 9Cubs vs. Nationals: Game time and live stream infoGame day: Tuesday, June 3, 2025Game time: 6:45 p.m. ETLocation: Washington D.C.Stadium: Nationals ParkTV channel: MASN and MARQLive stream: Watch LIVE with Fubo! (Regional restrictions may apply)

Watch Cubs vs. Nationals on Fubo!

Cubs stats and trendsCubs betting recordsThe Cubs have won 28, or 70%, of the 40 games they’ve played as favorites this season.Chicago has a record of 19-9, a 67.9% win rate, when favored by -143 or more by oddsmakers this season.The moneyline for this contest implies a 58.8% chance of a victory for the Cubs.So far this season, Chicago and its opponents have hit the over in 34 of 59 games with a total.The Cubs are 31-28-0 ATS in their 59 games with a spread this season.Cade Horton (Cubs probable starter)Horton makes the start for the Cubs, his fourth of the season. He is 2-0 with a 3.98 ERA and 16 strikeouts in 20 1/3 innings pitched.In his last time out on Wednesday, the righty tossed six innings against the Colorado Rockies, allowing two earned runs while surrendering four hits.The 23-year-old has amassed an ERA of 3.98, with 7.1 strikeouts per nine innings, in four games this season. Opponents are batting .266 against him.Horton is seeking his fourth straight outing lasting five or more innings. He averages 5.0 frames per appearance on the hill.The opposing Nationals offense has the 11th-ranked slugging percentage (.396) and is 16th in MLB play with 60 home runs. It has a collective .244 batting average, and is 18th in MLB with 480 total hits and 11th in MLB action scoring 265 runs.Cubs batting statsThe Cubs have hit 80 homers this season, which ranks fourth in the league.Hitters for Chicago have a combined .447 slugging percentage this season, which ranks third in MLB.The Cubs rank second in MLB with a .261 team batting average.Chicago has scored the second-most runs in the majors this season with 341.The Cubs have an OBP of .336 this season, which ranks third in MLB.Chicago ranks 11th in strikeouts per game (7.9) among MLB offenses.Nationals stats and trendsNationals betting recordsThe Nationals have been victorious in 26, or 52%, of the 50 contests they have been chosen as underdogs in this season.This season, Washington has been victorious 16 times in 35 chances when named as an underdog of at least +121 or worse on the moneyline.Oddsmakers have implied with the moneyline set for this matchup that the Nationals have a 45.2% chance of pulling out a win.Washington and its opponents have gone over the total this season in 28 of its 58 opportunities.The Nationals have an against the spread mark of 33-25-0 in 58 games with a line this season.Trevor Williams (Nationals probable starter)Williams (3-5 with a 5.69 ERA and 43 strikeouts in 55 1/3 innings pitched) makes the start for the Nationals, his 12th of the season.In his most recent appearance on Thursday, the righty went six scoreless innings against the Seattle Mariners while surrendering three hits.The 33-year-old has a 5.69 ERA and 7.0 strikeouts per nine innings across 11 games this season, while giving up a batting average of .291 to opposing hitters.Williams is looking to secure his second quality start of the year.Williams will try to collect his ninth outing of five or more innings pitched this season. He averages 5.0 innings per appearance.In one of his appearances this season he has not surrender an earned run.The opposing Cubs offense has the third-ranked slugging percentage (.447) and ranks fourth in home runs hit (80) in all of MLB. They have a collective .261 batting average, and are second in the league with 536 total hits and second in MLB action scoring 341 runs.Nationals batting statsThe Nationals average 1.0 home run per game to rank 16th in baseball with 60 total home runs.So far this year, Washington’s .396 slugging percentage is 11th in the majors.The Nationals are 19th in the majors with a .244 batting average.The offense for Washington is the No. 11 offense in MLB, scoring 4.5 runs per game (265 total runs).The Nationals’ .313 on-base percentage is 19th in MLB.

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