July 23, 2026, 6:48 a.m. ET

The Tampa Bay Rays (59-42) and the Toronto Blue Jays (46-56) wrap up a 4-game AL East series Thursday at Rogers Centre in Toronto, Ontario. First pitch is scheduled for 3:07 p.m. ET. Let’s analyze MLB odds around the Rays vs. Blue Jays odds and make our expert MLB picks and predictions for the best bets.

Season series: Rays lead 8-1

The Rays are aiming for their first series sweep since a 3-game sweep in Kansas City June 30-July 2. Tampa Bay hasn’t had a 4-game sweep since April 10-13, 2023, against the Boston Red Sox at Rogers Centre.

In Wednesday’s win, the Rays doubled up the Blue Jays 4-2 as slight underdogs (-108) as the Under (7.5) cashed. Rays RF Victor Mesa Jr. went 2 for 3 with a pair of RBIs and a stolen base. In a losing effort, Blue Jays C Alejandro Kirk finished 2 for 3 with a solo home run.

After a 5-game skid from July 12-19, Tampa Bay has won 3 in a row. The Over is 6-4-1 in the past 11 outings.

The Jays have dropped 4 in a row, while scoring 5 total runs in the skid. The Under is 3-2 in the past 5 outings, too, averaging just 1.2 runs per game.

Watch MLB on Fubo!Rays at Blue Jays projected starters

LHP Ian Seymour vs. RHP Shane Bieber

Seymour (6-2, 4.79 ERA) makes his eighth start (35th appearance). He has a 1.17 WHIP, 3.5 BB/9 and 10.5 K/9 in 67 2/3 innings.

Last start: No-decision, 3 IP, 3 ER, 2 H (2 HR), 2 BB, 4 K in 7-6 loss at Red Sox Saturday2026 road splits (2 starts, 15 appearances): 3-0, 6.23 ERA (26 IP, 18 ER), 6 HR, 14 BB, 33 K, 1.50 WHIP2026 day splits (3 starts, 16 appearances): 2-2, 5.50 ERA (34 1/3 IP, 21 ER), 6 HR, 13 BB, 33 K, 1.28 WHIPCareer vs. Blue Jays (2 starts, 6 appearances): 2-1, 5.02 ERA (14 1/3 IP, 8 ER), 2 HR, 5 BB, 16 K, 1.30 WHIP, 10.0 K/9

Bieber (1-1, 5.70 ERA) makes his sixth start. He has a 1.73 WHIP, 4.6 BB/9 and 7.2 K/9 in 23 2/3 innings.

Last start: Win, 6 IP, 0 ER, 3 H, 2 BB, 6 K in 1-0 home win vs. Chicago White Sox Saturday2026 home splits (3 starts): 1-0, 3.60 ERA (15 IP, 6 ER), 4 HR, 6 BB, 12 K, 1.53 WHIP2026 day splits (4 starts): 1-1, 6.16 ERA (19 IP, 13 ER), 6 HR, 9 BB, 15 K, 1.68 WHIPCareer vs. Rays (7 starts): 3-2, 3.27 ERA (41 1/3 IP, 15 ER), 3 HR, 11 BB, 51 K, 1.19 WHIP, 11.1 K/9Rays at Blue Jays odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 6:43 a.m. ET.

Moneyline (ML): Rays -110 (bet $110 to win $100) | Blue Jays -110 (bet $110 to win $100)Run line (RL)/Against the spread (ATS): Rays -1.5 (+154) | Blue Jays +1.5 (-190)Over/Under (O/U): 8.5 (O: -110 | U: -110)

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Rays at Blue Jays picks and predictionsPrediction

Rays 6, Blue Jays 5

RAYS (-110) is worth a look as Tampa tries to complete the 4-game sweep. Bieber looked much better last time out, but he is still working his way back into form and he can’t yet be trusted.

If you like the Blue Jays +1.5 (-190) a little bit, but can’t back them straight up, avoid the run line. Backing Toronto will cost you 2 times your potential return, and that’s too much.

PASS.

OVER 8.5 (-110) might be the best play on the board.

The Over is 8-4 in the past 12 games for the Blue Jays, while holding a 4-3 edge in the past 7 home games.

For the Rays, the Over is 3-2 in the past 5 games, while going 5-4 in the past 9 road contests.

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