Odds updated as of 11:11 p.m.

MLB action on Wednesday includes the Houston Astros taking on the San Francisco Giants.

Before you do any MLB betting on this game at FanDuel Sportsbook, here’s everything you need to know.

Houston Astros (61-59) vs. San Francisco Giants (49-70)Date: Wednesday, August 12, 2026Time: 3:45 p.m. ETVenue: Oracle Park — San Francisco, CaliforniaCoverage: NBCS-BA and SCHNAll MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.Moneyline: HOU: (-184) | SF: (+170)Spread: HOU: -1.5 (-111) | SF: +1.5 (-108)Total: 8 — Over: (-106) | Under: (-114)Astros vs Giants Probable Starting Pitchers

Probable Pitchers: TBA (Astros) vs TBA (Giants)

Neither the Astros nor the Giants has listed a starting pitcher for this matchup.

All MLB win probability predictions and picks are according to numberFire.
Prediction: Giants win (50.9%)

The Astros vs Giants moneyline has Houston as a -184 favorite, while San Francisco is a +170 underdog at home.The Astros are at the Giants and are favored by 1.5 runs (-111 to cover) on the runline. San Francisco is -108 to cover.Astros versus Giants, on Aug. 12, has an over/under of 8, with the over being -106 and the under -114.

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The Astros have been chosen as favorites in 46 games this year and have walked away with the win 24 times (52.2%) in those games.This season Houston has come away with a win one time in three chances when named as a favorite of at least -184 on the moneyline.The Astros and their opponents have hit the over in 65 of their 120 games with a total set by oddsmakers this season.The Astros have posted a record of 60-60-0 against the spread this season.The Giants have put together a 26-49 record in games they were the underdog on the moneyline (winning 34.7% of those games).When it has played as a moneyline underdog with odds of +170 or longer, San Francisco has a 2-3 record (winning 40% of its games).The Giants have played in 116 games with a set over/under, and have combined with their opponents to go over the total 54 times (54-53-9).The Giants are 52-64-0 ATS this season.Astros Player LeadersYordan Alvarez leads Houston in OBP (.435), slugging percentage (.624) and total hits (139) this season. He has a .323 batting average.Among qualifying hitters in the majors, he ranks first in batting average, first in on-base percentage, and first in slugging.Isaac Paredes has 21 doubles, a triple, 15 home runs and 46 walks. He’s batting .254 and slugging .418 with an on-base percentage of .348.Among qualifying hitters, his batting average ranks him 73rd, his on-base percentage 49th, and his slugging percentage 80th.Christian Walker has 102 hits this season and has a slash line of .238/.319/.453.Jeremy Pena has 13 home runs, 38 RBI and a batting average of .296 this season.Giants Player LeadersJung Hoo Lee has accumulated a .335 on-base percentage and a .447 slugging percentage, both team-high marks for the Giants. He’s batting .300.Including all the qualified hitters in MLB, he ranks 10th in batting average, 68th in on-base percentage and 54th in slugging percentage.Rafael Devers is batting .247 with 27 doubles, a triple, 24 home runs and 49 walks. He’s slugging .472 with an on-base percentage of .320.He is currently 87th in batting average, 92nd in on-base percentage and 32nd in slugging percentage among all qualifying batters.Willy Adames is hitting .221 with 24 doubles, a triple, 19 home runs and 35 walks.Bryce Eldridge is hitting .248 with 15 doubles, 11 home runs and 39 walks.8/10/2026: 6-3 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +132)4/2/2025: 6-3 SF (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -166, Underdog Moneyline: +140)4/1/2025: 3-1 SF (Favorite: Giants, Spread: -1.5, Total: 8, Favorite Moneyline: -134, Underdog Moneyline: +114)3/31/2025: 7-2 SF (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -126, Underdog Moneyline: +108)6/12/2024: 5-3 SF (Favorite: Giants, Spread: -1.5, Total: 7, Favorite Moneyline: -120, Underdog Moneyline: +102)6/11/2024: 3-1 HOU (Favorite: Giants, Spread: -1.5, Total: 8, Favorite Moneyline: -118, Underdog Moneyline: -100)6/10/2024: 4-3 SF (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -116, Underdog Moneyline: -102)5/3/2023: 4-2 SF (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -154, Underdog Moneyline: +130)5/2/2023: 2-0 SF (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -205, Underdog Moneyline: +172)5/1/2023: 7-3 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -198, Underdog Moneyline: +166)

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