On Wednesday, the Washington Nationals (28-32) are hosting the Chicago Cubs (38-22), at 6:45 p.m. ET. The Cubs have taken three in a row.

The Nationals (+115 underdog moneyline odds to win) hit the field versus the Cubs (-136). The scheduled starters are Matthew Boyd (5-2) for the Chicago Cubs, and MacKenzie Gore (2-5) for the Washington Nationals.

Yesterday, the Cubs picked up an 8-3 win over the Nationals, with Cade Horton (5.1 IP, 3 R, 6 H, 3 K) earning the win for the Cubs. Michael Busch finished 3 for 4 with a triple, a home run and three RBIs to lead the offensive showing. Trevor Williams (4.1 IP, 5 R, 5 H, 4 K) took the loss for the Nationals.

Here is what you need to get ready for Wednesday’s Cubs vs. Nationals contest, including viewing options.

Chicago Cubs vs. Washington Nationals odds, line and spread

MLB odds courtesy of BetMGM Sportsbook. Odds updated Wednesday at 12:16 a.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.

Favorite: Cubs (-136, bet $136 to win $100)Underdog: Nationals (+115, bet $100 to win $115)Over/under: 8.5Cubs vs. Nationals: Game time and live stream infoGame day: Wednesday, June 4, 2025Game time: 6:45 p.m. ETLocation: Washington D.C.Stadium: Nationals ParkTV channel: MASN and MARQLive stream: Watch LIVE with Fubo! (Regional restrictions may apply)

Watch Cubs vs. Nationals on Fubo!

Cubs stats and trendsCubs betting recordsThe Cubs have been favorites in 41 games this season and won 29 (70.7%) of those contests.Chicago has a record of 20-9, a 69% win rate, when favored by -136 or more by sportsbooks this season.The sportsbooks’ moneyline implies a 57.6% chance of a victory for the Cubs.Games involving Chicago have gone over the total set by bookmakers in 35 of 60 chances this season.The Cubs have an ATS record of 32-28-0 in 60 games with a spread this season.Matthew Boyd (Cubs probable starter)Boyd (5-2) takes the mound for the Cubs in his 12th start of the season. He has a 3.08 ERA in 61 1/3 innings pitched, with 64 strikeouts.In his most recent appearance on Thursday, the lefty went six innings against the Colorado Rockies, giving up no earned runs while surrendering four hits.The 34-year-old has put up an ERA of 3.08, with 9.4 strikeouts per nine innings, in 11 games this season. Opponents have a .266 batting average against him.Boyd has seven quality starts this year.Boyd has pitched five or more innings in a game 10 times this year entering this matchup.He has had three appearances this season in which he did not surrender an earned run.The opposing Nationals offense has the 13th-ranked slugging percentage (.395) and ranks 18th in MLB play with 60 home runs. It has a collective .244 batting average, and is 18th in MLB with 488 total hits and 11th in MLB action scoring 268 runs.This season, the 34-year-old ranks 30th in ERA (3.08), 50th in WHIP (1.255), and 23rd in K/9 (9.4) among pitchers who qualify.Cubs batting statsThe Cubs’ 81 home runs rank fifth in Major League Baseball.Fueled by 211 extra-base hits, Chicago ranks third in MLB with a .448 slugging percentage this season.The Cubs’ .262 batting average is among the best in baseball, ranking second in MLB.Chicago leads MLB with 349 runs scored this season.The Cubs have an OBP of .335 this season, which ranks third in MLB.Chicago ranks 10th in MLB in strikeouts per game with an average of 7.9 whiffs per contest.Nationals stats and trendsNationals betting recordsThe Nationals have been chosen as underdogs in 51 games this year and have walked away with the win 26 times (51%) in those games.This season, Washington has been victorious 19 times in 40 chances when named as an underdog of at least +115 or worse on the moneyline.The Nationals have an implied victory probability of 46.5% according to the moneyline set for this matchup.Washington and its opponents have gone over in 29 of its 59 games with a total set by sportsbooks this season.The Nationals are 33-26-0 against the spread in their 59 games with a line set by sportsbooks this season.MacKenzie Gore (Nationals probable starter)Gore (2-5) takes the mound first for the Nationals in his 13th start of the season. He has a 3.16 ERA in 68 1/3 innings pitched, with 101 strikeouts.In his last appearance on Friday against the Seattle Mariners, the lefty tossed six scoreless innings while surrendering four hits.Over 12 games this season, the 26-year-old has amassed a 3.16 ERA and 13.3 strikeouts per nine innings, while allowing a batting average of .241 to opposing batters.Gore is trying to build on a second-game quality start streak in this matchup.Gore will try to continue a three-game streak of going five or more innings (he’s averaging 5.7 innings per appearance).He has held his opponents without an earned run in two of his 12 outings this season.The opposing Cubs offense has the third-ranked slugging percentage (.448) and ranks fifth in home runs hit (81) in all of MLB. They have a collective .262 batting average, and are third in the league with 545 total hits and first in MLB action scoring 349 runs.The 26-year-old ranks 36th in ERA (3.16), 42nd in WHIP (1.200), and first in K/9 (13.3) among qualifying pitchers in MLB action this season.Nationals batting statsThe Nationals average 1.0 home run per game to rank 18th in baseball with 60 total home runs.So far this year, Washington ranks 13th in baseball with a .395 slugging percentage.The Nationals rank 19th in MLB with a .244 batting average.The offense for Washington is the No. 11 offense in baseball, scoring 4.5 runs per game (268 total runs).The Nationals’ .312 on-base percentage ranks 19th in baseball.

Watch the MLB on Fubo!