The Blue Jays (68-71) and the Guardians (70-68) continue their crucial three-game series in Cleveland tonight. The Guardians strengthened their hold on the final Wild Card with a 6-1 win last night over the Jays in the series opener. With the win, Cleveland extended their lead over the Blue Jays to 1.5 games in the race for the final Wild Card spot.

Toronto arrived in Cleveland after taking three of four from Seattle over the weekend but saw that momentum snuffed out by Gavin Williams. The Guardians’ ace was elite striking out 13 and allowing just one unearned run over seven innings. Patrick Bailey, Angel Genao, and Angel Martinez each ripped two-run homers to provide the offense for Cleveland. With the win, the Guardians are now 11-4 since August 12.

Toronto sends its ace, Dylan Cease (9-5, 2.33 ERA) to the mound tonight. Among the Cy Young favorites in the American League, Cease has been lights out for the last two months. In just two of his last 11 starts Cease has allowed three earned runs and in five of those 11 he has not allowed a run (earned or otherwise). Cease has thrown 67 innings since July 1 and allowed just 11 earned runs while striking out 89. Cleveland counters with left-hander Joey Cantillo (9-7, 3.70 ERA). His latest outing came August 26 against the Angels, when he worked six innings and allowed three runs (two earned) on two hits in a Cleveland victory. Cantillo has been particularly effective lately, posting a 2.16 ERA across his last three starts. During that stretch he has allowed just four earned runs in 16â…” innings.

Cleveland has won three of five games against Toronto this year and can clinch the season series with a win tonight.

Lets dive further into tonight’s game and find a sweat or two.

We’ve got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch first pitch, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.

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Game Details and How to Watch: Blue Jays vs. GuardiansDate: Wednesday, September 2, 2026Time: 6:40PM ESTSite: Progressive FieldCity: Cleveland, OHNetwork/Streaming: MLB.TV, Sportsnet, CLEGuardians.TV

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The Latest Odds: Blue Jays vs. GuardiansThe latest odds as of Wednesday courtesy of DraftKings:Moneyline: Toronto Blue Jays (-131), Cleveland Guardians (+109)Spread: Blue Jays -1.5 (+135), Guardians +1.5 (-163)Total: 7.0 runs

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Probable Starting Pitchers – Blue Jays vs. Guardians for September 2Guardians: Joey Cantillo
Season Totals: 136.1 IP, 9-7, 3.70 ERA, 1.45 WHIP, 145K, 70 BBBlue Jays: Dylan Cease
Season Totals: 150.1 IP, 9-5, 2.33 ERA, 1.05 WHIP, 217K, 65 BBWho’s Hot? Who’s Not! Blue Jays vs. GuardiansDylan Cease has struck out 8+ hitters in 4 of his last 5 startsPatrick Bailey is 4-7 in his career against Dylan CeaseJose Ramirez is just 6-30 against CeaseNathaniel Lowe has homered twice in 13ABs against CeaseKazuma Okamoto is 2-3 including 1 HR in his career against Joey CantilloJoey Cantillo has struck out 5+ hitters in 6 of his last 8 startsSteven Kwan has hit safely in 9 of his last 11GP (17-46)

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Top Betting Trends & Insights: Blue Jays vs. GuardiansThe Jays are 67-72 on the Run Line this seasonThe Guardians are 71-67 on the Run Line this seasonThe OVER has cashed 68 times in Toronto’s 139 games this season (68-66-5)The OVER has cashed 65 times in Cleveland’s 138 games this season (65-73)

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Expert picks & predictions: Blue Jays vs. Guardians – September 2Rotoworld Bet Best Bet

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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.

Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.

Here are the best bets our model is projecting for tonight’s game between the Guardians and the Blue Jays:Moneyline: Rotoworld Bet is leaning towards a play on the Blue Jays on the Moneyline.Spread: Rotoworld Bet is recommending a play on the Blue Jays on the Run Line.Total: Rotoworld Bet is staying away from a play on the Game Total of 7.0

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